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Soft-tissue measurements at the index finger: age and sex characteristics.

Measurements of the soft-tissue width and phalanx width of the index finger were made in 402 normal individuals (270 women and 132 men, age range 20--89 years) in order to establish age-sex characteristics. Men have a significantly larger total finger and phalanx width than women in all age groups. In both sexes a statistically significant increase with age in phalanx width and total finger width is found. The soft-tissue index and soft-tissue thickness is not influenced by age.

Adult

Secondary sex characteristics of boys 12 to 17 years of age: the U.S. Health Examination Survey.

Data from the United States Health Examination Survey, Cycle III, were used to describe secondary sexual characteristics and their relationship to skeletal age in a representative sample of adolescent males aged 12 to 17 years. This survey utilized a national probability sample of youths selected to represent the U.S. population with respect to age, race, sex, geographic region, and socioeconomic status. Good concordance was found between Tanner stages for pubic hair and for genitalia. Sexual characteristics developed similarly for white and black boys, and socioeconomic status did not influence this development. Skeletal age and serum urate levels were closely related to development of pubic hair and genitalia. These data permit the physician to compare the development of individual patients with a representative sample of contemporaneous U.S. boys.

Adolescent

[Hormonal regulation and hormone therapy in childhood and adolescence. Part 1: development of endocrine glands, hormone production, menarche and secondary sex characteristics].

The growth curves of the endocrine glands in female puberty are described. Adrenarche with an elevated production of adrenal dehydroepiandrosterone marks the beginning of prepuberty. By decrease of hypothalamic sensitivity to sexual steroids begins the deviation of FSH and LH levels. Significant increases of gonadotrophins and prolactin occur during sleep. There is a good correlation between bone age, Tanner-stages of breast and pubic hair development and steroid hormone levels. Criteria of maturity for young girls including menarche and ovulation are given.

Adolescent

[Influence of temperature on the rate of spermatogenesis, duration of spermatogenic activity and development of secondary sex characteristics in the wall-lizard, Lacerta muralis L. (Reptilia, Lacertidae)].

A series of experiments was carried out primarily between the 22nd of March and the 27th of June, on 60 Lacerta muralis maintained either under semi-natural conditions in large enclosures or in constant-temperature cabinets maintained at 17.5 degrees C, 20 degrees C, 22.5 degrees C and 27.5 degrees C with a natural photoperiod. Following an injection of tritiated thymidine, the animals were sacrificed at regular intervals and the rate of spermatogenesis was deduced from the progression of the radioactive front in the seminiferous epithelium. The following results were obtained: 1. The rate of spermatogenesis is temperature dependent and increases by a factor of approximately 1.2 per degree centigrade between 17.5 and 27.5 degrees C. The rate is seven times greater at 27.5 degrees C than at 17.5 degrees C. 2. Under semi-natural conditions the interval leptotene-spermatozooid lasts 70 days, slightly less than that found at a constant temperature of 22.5 degrees C. 3. Under semi-natural conditions the rate of spermatogenesis was similar to that in August-September, April-May and May-June which indicates that the lizards were able to maintain their body temperature at an equivalent level by behavioural temperature regulation during the greater part of their activity period. 4. Under semi-natural conditions, or at temperatures in excess of 22 degrees C, spermiogenesis lasts 1.8 times as long as meiosis. 5. At constant temperatures lower than 21 degrees C the development of the cellular lineage is aressted at the young spermatid stage. 6. Constant temperatures between 17.5 and 22.5 degrees C had no effect on the time of involution of the testis at the start of summer. 7. At low constant temperatures, secondary sexual characteristics regress before the usual time: after 4 weeks at 20 degrees C and after 8 weeks at 17.5 degrees C. An expected regression after 8 weeks produced after exposure to a temperature of 22.5 degrees C is probably due to factors other than temperature. 8. In the case of different individuals kept either under natural, semi-natural or experimental conditions, there was no close relationship observed between the time of involution of the seminiferous tubules and regression of secondary sexual characters. ters. 9. These results confirm the concept of endogenous control of sexual regression at the commencement of summer and argue in favour of 2 separate gonadotrophic hormones in reptiles.

Animals

Perceived age and sex characteristics of voices of institutionalized children with Down's syndrome.

It was hypothesized that the voices of children with Down's syndrome would be perceived as younger than their true chronological age and that perceptual auditors would have considerable difficulty in identifying the correct sex of these children by voice alone. Perceived age and sex were investigated in 20 institutional children with Down's syndrome who were matched for sex and age with a control group of 20 normal children. Randomized matched verbal samples were played backwards to a group of 16 listener/judges who rated the samples as to age and sex. The results indicated that the voices of these Down syndrome children were perceived as being more than 2 yr. younger than their group mean age and that there was a negative correlation between the biological sex of such children and their perceived sex.

Adolescent

[Architecture of the human skull cap in the region of the pars bregmatica suturae sagittalis. II. Sex characteristics].

There has previously been no treatise on the inner architecture of the human cranial vault other than those dealing with common "age changes". Such a treatise ought to refer to a particular segment of the vault demonstrate the peculiar structure according to age in both sexes, and also take into consideration their normal variability as presupposition for using the results in estimating the age of prehistoric skeletal material. With the help of thin sections across the sagittal suture and the adjoining cranial vault 10 mm behind the bregma findings about the specific structure as to age and sex and their expected variability are demonstrated by more than 200 cases taken from the recent population. According to the results in hand there exists a contradiction to the opinions hitherto existing about a distinct age dependence in the bone structure and distinct sex differences in the findings of the structures of the Ist order. Though data about changes in the anatomical construction of the human cranial vault during the ontogenesis are to be correctly obtained only with the help of longitudinal investigation, the crosssectional investigation produced only differences between the age classes. Real differences were not to be found, but there are to be derived possible tendencies of development for the calvarial thickness, for the relation between the compact bone (tabula externa, tabula interna) and the porous bone (diploë), of the porosity in the diploë and the obliteration of the suture in the course of increasing age. No significant sex differences were found but there are sex peculiarities or at least inclinations to it. The use of the findings taken from the cross-sectional aspect of the cranial vault in order to estimate the age at death and the sex as well as indications of possible individual peculiarities, at present ead to a sufficiently reliable diagnosis only within a polysymptomatical practice.

Adolescent

Biological activity of some steroidal compounds in the adult and larval frogs.

Four steroids were tested for their biological activity, using the sex-steroid-dependent redevelopment of the secondary sex characteristics in adult frogs and gonadal sex differentiation in larval frogs as end points. In adult frogs, 19-norprogesterone and 6-chloro-17alpha-hydroxy-4, 6-pregnadiene-3,20-dione had antiandrogenic and antiestrogenic effects. 2alpha, 17alpha-Dimethyl-DHT and 2alpha-methyl-DHT were potent androgens and effective antiestrogens. In the larval frogs, all four compounds had a masculinizing effect upon the undifferentiated gonads.

Animals

[Secretory type and the X-sex chromatin characteristics of persons with peptic ulcer].

Blood groups according to ABO and Rh systems were tested in 137 ulcer patients as well as the secretory state. The titre of blood group ABH antigens was determined in the same patients, secreted in saliva and gastric juice. The results are compared with those obtained from the examination of a control group of 30 clinically healthy subjects. X-sex chromatin in the cells of biopsy mucosa was examined in 40 ulcer patients, taken from the ulcer area after gastroscopy. As a control, X-sex chromatin was studied in smears from exfoliated oral mucosa in the same subjects. The data confirm the presence of genetic predisposition to ulcer disease development in subjects from blood group O (alpha, beta) and non-secretory type. Low titres of blood group antigens were found in the secretory patients. Differences in X-sex chromating characteristics were observed between bucal mucosa and the mucosa from the ulcer area.

ABO Blood-Group System

Reproductive capacity of the mentally retarded.

Ninety-seven mentally retarded females were studied to evaluate parameters of growth and development of secondary sex characteristics and the incidence of ovulation. These patients were selected on the basis of age and etiological classification. Patients were classified as Down's syndrome, brain damaged, or undifferentiated. The following parameters of growth and development were studied: anthropometric, bone age, and sexual maturation. Sexual maturation studies consisted of breast development, pubic hair, axillary hair, menarche, menstrual pattern, and ovulatory patterns. The following observations were made from this study: 1. Physical growth and secondary sexual development were retarded in all parameters. 2. The undifferentiated and brain damaged groups showed almost identical patterns of growth and development of secondary sexual characteristics. 3. The Down's syndrome group was the most retarded in physical growth and in secondary sexual development. 4. Skeletal age was a better guide than chronological age or height and body weight to the prediction of development of secondary sex characteristics and age at onset of menarche. 5. In 26 mentally retarded females who had achieved menarche the incidence of ovulation was approximately 60 percent.

Adolescent

Anthropometric and maturation measurements of children, ages 5 to 14 years, in a biracial community--the Bogalusa Heart Study.

An epidemiological survey of anthropometric and maturation variables was conducted on 3,524 children from the biracial community of Bogalusa, Louisiana. These children, representing 93% of the population, were examined during the school year September 1973 through May 1974. Black boys differed slightly from white boys in height and weight; black girls were taller and heavier than white girls. The black children had longer upper arm lengths and smaller upper arm circumferences than the white children. The median ponderosity (weight divided by the cubed height) decreased with increasing heigth for the four race-sex groups, and a skewed distribution of ponderosity indicated an excess of heavy children among the tall. Based on the Tanner criteria for grading secondary sex characteristics, maturation occurred earlier in the more ponderous girls, although such was not the case for boys. Whereas the Tanner secondary sex characteristics appeared earlier in black girls, white girls reported menarche earlier. The racial and sexual differences known to exist in triceps skinfold were observed for this population. No statistically significant difference was observed overall for height and weight between children within this one community and those of the National Health Examination Survey. However, Bogalusa girls at the 95th percentile were heavier after age 11 than girls of the United States. Also, there was a tendency for white girls in this community to report reaching menarche at an earlier age than black girls, which contrasts slightly with the national sample.

Anthropometry

Adults' perceptions of children's independence and other sex-role characteristics as a function of child's gender label.

Male and female college students were presented with a photograph labeled as a 5-yr.-old boy or girl and heard statements attributed to the child. They then rated the child on sex-role traits and responded to open-ended questions about the child. The primary findings involved sex of child by sex of adult interactions on ratings of independence and leadership: in both cases, same-sex children were rated higher than opposite-sex children. There was also some evidence that women having high contact with children rated the child more extremely on opposite-sex traits than did those with little contact.

Adolescent

Onset of puberty in MX and DZ twins.

A twin study on the significance of genetic factors for the variation in peak height and peak weight velocity, as well as in age at menarche and the development of secondary sex characteristics, is presented. Evidence of a rather strong genetic regulation of the occurrence of puberty was obtained in the analysis. The maximal height or weight gain (in cm/year of kg/year) seems to be, at least in girls, less influenced by genetic factors than the age at which it appears.

Adolescent

[Is enostosis frontalis a disease process? (author's transl)].

2851 radiodiagnostic examinations of the skull made in a psychiatric hospital between 1958 and 1977 were reviewed for enostosis frontalis. Out of 1398 female patients there were 125 cases of enostosis frontalis, whereas out of the 1453 male there were only 5. Hence, in females, this is a frequent condition (9%) and shows no correlation with manifest hormonal disease or any particular neuro-psychiatric disturbance. Enostosis frontalis in females can be considered to be an inconstant secondary sex characteristic. In male patients this condition is extremely rare (0.32%). The case histories of the male patients are reported. Endocrine disturbances, cerebral dysplasia and psychiatric disease in connection with mental retardation seem to be associated with enostosis frontalis in men.

Adult

Influence of vitamin B-6 upon reproduction and upon plasma and egg cholesterol in chickens.

Vitamin B-6 deficiency in the laying hen causes an immediate anorexia, loss of body weight, greatly reduced body fat stores and severe effects upon primary and secondary sex characteristics resulting in severely reduced hatchability culminating in complete cessation of egg production. While inanition may have been largely responsible for involution of the ovaries and oviducts in the vitamin B-6 deficient hens, regression of combs and wattles appears to be a more specific sign of vitamin B-6 deficiency. Serum cholesterol levels of vitamin B-6-deficient hens were lower than those of hens receiving an adequate diet. Egg cholesterol values remained relatively constant regardless of dietary B-6 levels or of alterations in serum cholesterol. No ataxia or mortality was observed in vitamin B-6-deficient hens or roosters. The effects of vitamin B-6 deficiency were almost completely reversed upon repletion of the hens with adequate dietary vitamin B-6.

Animal Feed