PubMed Health⌕ Search

SEARCH · PubMed Health

Results for “Sinusitis”

Explore indexed PubMed citations for clinical trials, systematic reviews and public health research. Read source abstracts and follow each citation to its original PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1975

[Vagal effect on sino-atrial node frequency and A-V overdrive in hypersensitive carotid sinus reflex and sick sinus syndrome].

Two syndromes, hypersensitive carotid sinus reflex (HCSR) and "sick sinus syndrome" (SSS) were studied in 28 patients, 6 of whom served as controls. Carotid sinus pressure was performed during sinus rhythm (CSP 1) and atrial stimulation just above the sinus rate (CSP 2). Overdrive suppression was also tested. Vagal stimulation provoked different effects in HCSR and in SSS. The vagal reaction to CSP 1 was more manifest in HCSR than in both SSS and the controls. After CSP 2 A-V conduction was delayed longer in HCSR than in SSS and the controls. Following atropine, the vagal effect on HCSR was more pronounced than on SSS and the controls. With HCSR, the duration of vagal influence on R-R intervals (A-V conduction) was significantly shorter than on P-P intervals (sinus rate). After atropine, there was less vagal effect on A-V conduction than on the sinus rate in HCSR, meaning that A-V conduction was shorter and less affected than the sinus rate by carotid sinus pressure. Prolonged suppression following overdrive established the diagnosis of SSS. This suppression was found not to be affected by atropine. A dependency of suppression on the rate and duration of overdrive could not be ascertained for SSS. The newly formulated "postdrive P-P interval recovery time" subdivided SSS in such a way that two different degrees of severity could be illustrated. The conclusion was that HCSR was caused by an excessive reaction to vagal stimulation rather than by a dysfunction of the sinus node or A-V conduction system. SSS might be based on tissue damage in the sinus nodal region but it did not show increased sensitivity to vagal influence.

Adult↗
PubMed1977

[Peroperative sinus arrest in a patient with sick sinus syndrome (apropos of a case)].

A sinus arrest occured during a surgical intervention in a patient suffering from a sinus nodal dysfunction. The Fentanyl acetate used as an analgésic, seems to have played an important role in the genesis of the accident, depressing sinusal and junctional automatisms. Though unusual, this complication leads to a further investigation in preoperative period for a possible sinus nodal dysfunction in order to anticipate an extreme preoperative bradycardia (sino atrial block) treated with intravenous administration of isoprenaline. Intraveinous atropine test is a simple preoperative technique of research in front all unexplained sinus bradycardia.

Arrhythmia, Sinus↗
PubMed1975

[The effect of various antibiotics on the mixed flora of the maxillary sinus in sinusitis(author's transl)].

The effect of four frequently used antibiotics on the germs of the sinus maxillaris was studied. For this purpose germs of the sinus max. rinsing fluid, got from 127 patients, were cultured under nearly the same physical and chemical conditions which can be expected in the sinus itself. Each antibiotic substance was studied with three different comcentrations in the culture medium. By extrapolation of the linear regression between some characteristical parameters of the culture absorbancy development and the concentration, the inhibitory concentration can be estimated. The efficacy decreases in the following order: Doxycyclin greater than Gentamycin greater than Ampicillin greater than Lincomycin. An inhibitory concentration results, if the antibiotics are instilled in the sinus itself. The general side effects can be neglected but not at all the local ones. Investigations in this direction are still going on. As a preliminary report, 700 instillations of Lincomycin turned out with no incident.

Administration, Topical↗
PubMed1979

Surgical treatment of chronic hyperplastic sinusitis and maxillary sinus empyema of oral/dental origin.

Twelve patients with maxillary hyperplastic sinusitis or maxillary sinus empyema of oral/dental etiology have been treated according to a modified surgical technique. The treatment was initiated by several oro-nasal irrigations and drainage facilitated by an intact semilunar hiatus. This was followed by a surgical procedure including conservative curettage of inflamed sinus mucosa, adequate closure of the oro/antral communication, with establishment of a postoperative oral antrostomy. This antrostomy, through the canine fossa, was established by a vacuum drain, enabling continuous postoperative irrigation and aspiration. The rationale for this technique is discussed. A total of 12 patients operated according to this technique are described. Complete clinical and radiographic healing in all patients was observed over a postoperative period ranging from 6-12 months.

Adult↗
PubMed1975

[The effect of drugs on "sino-atrial conduction time" and on sinus-node automaticity in man].

The effect of atropine, propafenone, and disopyramide on sinus node automaticity and "sino-atrial conduction" was tested in normal patients and patients with the sick sinus-syndrome. "Sino-atrial conduction time" was estimated indirectly by the extrastimulus technique. Atropine (n = 11) caused a significant increase in heart rate in all patients. The sinus node recovery time was shortened in 10 patients. "Sino-atrial conduction time" decreased on an average 35% (P less than 0.01). Three patients with a sick sinus-syndrome demonstrated a change of the pattern of the postextrasystolic pauses indicating great improvement in sino-atrial conduction. Propafenone (n = 10) led to a significant prolongation of the sinus node recovery time by 17% and of the "sino-atrial conduction time" by 27%. Disopyramide (n = 8) had no significant influence on heart rate and "sino-atrial conduction time". Sinus node recovery time was not changed in 6 patients. However, in two patients with a sick sinus-syndrome a dangerous prolongation of the sinus node recovery time after application of disopyramide occurred. The results indicate that atropine enhances sinus node function and sino-atrial conduction. On the other hand, propafenone and disopyramide exert either a depressant influence on sinus node automaticity or on sino-atrial conduction.

Atropine↗
PubMed1978

Acute ischemic sinus node dysfunctions in dogs.

The effects of the occlusion of the two main atrial arteries irrigating the sinus node on sinus rhythm and postpacing sinus recovery were studied in 12 anesthetized dogs. Records of spontaneous rhythm and of postpacing sinus recovery were taken at control and hourly for 6 hours after the occlusion. The spontaneous cycle length (AA interval) was 335 +/- 11 ms at control and 416 +/- 17 ms (mean +/- SE) (p less than 0.005) one hour after the occlusion. It remained nearly unchanged during the following 5 hours of observation. The occlusion also shortened atrioventricular conduction time (AV interval) and reduced P-wave amplitude in ECG lead II in 9 of these dogs. While the control postpacing sinus recovery time was 397 +/- 13 ms, the 1-hour value was 715 +/- 165 ms. This prolongation persisted during the first four postocclusion hours but was less marked during the last two hours of observation. Moreover, the postpacing mode of return of the AA intervals to their prepacing value (sinus recovery pattern) became characteristically slow and progressive after occlusion, complete postpacing recovery often occurring only after 100 or more beats. Sequences of escape atrial and/or AV junctional rhythms were frequently seen during this recovery. Atrial extrasystoles and short sequences of atrial tachycardias were observed in most dogs after occlusion. Conversely, none of these changes occurred during a 6-hour experimental time in 5 control dogs in which the same protocol, occlusion excepted, was repeated. These observations show that the sinus node function in the dog is consistently affected by impairing its blood supply. Ischemic dysfunctions include sinus slowing, pacemaker shift, prolonged sinus recovery time, delayed postpacing recovery and supraventricular tachyarrhythmias.

Animals↗
PubMed2026

Imaging-based surgical stratification of parasagittal meningiomas involving the superior sagittal sinus: a case analysis of 62 patients.

OBJECTIVE: The objective was to evaluate the Superior Sagittal Sinus Involvement Grading (SSIG) system as an imaging-based surgical stratification framework for parasagittal meningiomas adjacent to the superior sagittal sinus (SSS) and to assess its relationship with established sinus invasion grading, venous sinus patency, and operative strategy. METHODS: In this single-center retrospective cohort study, the authors included 62 consecutive parasagittal meningioma resections performed by a single surgeon. SSIG grade was assigned primarily on contrast-enhanced coronal MRI, with CT/MR venography used when available to evaluate sinus patency and collateral venous drainage. Operative variables, resection strategy, and clinicopathological factors were compared across SSIG and Sindou grades, and postoperative complications were compared between low- and high-involvement SSIG groups. RESULTS: SSIG correlated significantly with Sindou grade (rs = 0.790, &#x3c4;b = 0.702, both p < 0.001), and among patients with available venous imaging, it also correlated with the venous sinus involvement grade (rs = 0.742, &#x3c4;b = 0.665, both p < 0.001). With increasing SSIG grade, operative time, intraoperative blood loss, and intraoperative fluid administration increased (p = 0.012, p = 0.008, and p = 0.007, respectively). Compared with the low-involvement group (SSIG grades 1, 2, and 4a), the high-involvement group (SSIG grades 3, 4b, and 5) was less likely to achieve Simpson grade I resection and more likely to adopt Simpson grades II-III strategies (66.7% vs 13.6%, p < 0.001; OR 12.667). Surgery-related complication rates did not differ significantly between groups. The mean follow-up was 13.3 &#xb1; 7.9 months, with no radiographic recurrence or progression at last follow-up. CONCLUSIONS: SSIG characterizes parasagittal meningiomas by integrating sinus invasion, venous patency, falcine extension, and parasagittal convexity involvement on preoperative imaging. This surgically oriented framework may help anticipate operative exposure, sinus handling, and resection strategy. Its predictive value for complications and long-term oncological outcomes requires validation in larger cohorts with longer follow-up.

Humans↗
PubMed1979

Paranasal sinus aspergillosis.

Four cases of aspergillosis of the paranasal sinuses seen recently at the North Carolina Baptist Hospital are reported. Paranasal sinus aspergillosis is prone to develop in patients living in the southeastern states because those states 1. have an agricultural economy and 2. have a hot, humid climate that causes a high incidence of nasal and sinus disorders. The increasing use of immunosuppressive and oncological drugs should further increase the incidence of aspergillosis. Diagnosis of aspergillosis of the paranasal sinuses requires a high index of suspicion which should be present particularly for a patient who has unilateral sinusitis that does not respond to routine therapy, or who has a localized sinus mass or bony erosion. Immunodiffusion tests are specific for aspergillosis. Treatment consists of surgical removal of the diseased mucosa and adequate aeration and drainage of the sinus. Culture of the specimen on Sabouraud's agar will confirm the diagnosis.

Aged↗
PubMed1977

[Comparison of x-ray, echography and sinumanometry findings in paranasal sinusitis (author's transl)].

Comparative echography and x-ray findings in suspected paranasal sinus disease reveal a good liability of negative x-ray reports. Positiv findings i.e. the diagnosis of mucous membrane thickening in the maxillary sinus and clouding of the frontal sinus are often misleading. Echography is reliable in diagnosing retention of sinus secretions. The patency of the maxillary ostium for air was tested in patients with complete opacity of the sinus. There was a significant difference between air or fluid containing sinuses, using echography as a control. Complete radiographic opacity has no bearing on ostial patency. In air containing sinuses with radiographic opacity, ostial permeability is slightly affected, the ostium nevertheless being patent for respiratory pressure changes.

Humans↗
PubMed1975

[The endoscopy of paranasal sinuses. Diagnostic and therapeutic possibilities (author's transl)].

This paper deals with further experiences in endoscopy of the maxillary sinus and in possibilities of endoscopy of frontal and sphenoidal sinuses. Some coloured photographs taken during endoscopy are shown. As the result of 301 sinuscopies of maxillary sinus performed, it could be shown that in 36% of the cases x-ray findings didn't exactly correspond with the endoscopy findings. In further 22% there was no correlation at all between the x-rays and findings at operation. This shows the great importance of sinuscopy and reveals its diagnostic values. The author used the endoscopy of the maxillary sinus not only for diagnostic purposes but for the treatment of chronic purulent sinusitis as well as complete removal of the socalled solitary cysts of the mucous membrane. A therapeutic gap between the two extreme (conservative treatment on one side and radical surgery Caldwell-Luc on the other side) ist bridged using this method. Finally the indications for endoscopy of maxillary and frontal sinuses are shown clearly in a table.

Adult↗
PubMed2026

Retrosigmoid craniotomy surgical guide: The way forward for precise exposure of the transverse-sigmoid sinuses.

INTRODUCTION: The retrosigmoid craniotomy is the workhorse approach to the cerebellopontine angle. Accurate localisation of the transverse-sigmoid junction (TSJ) is key for optimised exposure and cerebellar retraction. Various methods, both anatomical and navigational, have been used but with suboptimal results. We utilised a 3D-printed retrosigmoid surgical guide in an attempt to overcome this and report our early outcomes and experiences in the design, production and utilisation of the guide. METHODS: This is a prospective cohort study of the patients with retrosigmoid craniotomies performed using the surgical guides. Patient demographics and diagnoses, along with the accuracy of the planned burrhole and craniotomy, need for craniotomy extension, presence of venous sinus injury, set-up time, and cost were reported. RESULTS: There were ten cerebellopontine angle cases in which the surgical guides were utilised, three petrous meningiomas, two trigeminal neuralgias, two metastasis, and three other tumours. The planned burrhole and craniotomy were precise in all cases with accurate exposure of the TSJ and no requirement for craniotomy extension. The mean set up time was 3.9&#xa0;min, and the mean cost of the surgical guides was USD 470.90. One elderly patient had an intraoperative transverse sinus injury related to adherent dura that was planned for exposure. CONCLUSION: The 3D-printed surgical guide is a potential solution to the rapid, precise and consistent identification of the TSJ when performing a retrosigmoid craniotomy. We present our early experience and discuss nuances in the designing, production, and intraoperative phases to optimise the precision of this guide. We suggest two methods to avoid sinus injury in elderly patients: either to plan the craniotomy to the edge of the sinus, or to plan sinus exposure but to use burr drills rather than the osteotome, as in our case, to expose the sinus.

Humans↗
PubMed1976

[Sinus node function in man. Statistical analysis].

The sinus function of 60 patients was studied by atrial stimulation at a fixed rate, and also at a rate linked with the preceding sinus cycle. These patients were divided into 3 groups according to the surface-recorded ECG; 10 had clear evidence of sinus dysfunction, 23 had an isolated sinus bradycardia, and 27 were considered as controls a their sinus rate was above 60/min., with a normal PR interval. Calculation of the limits of tolerance showed that at the 5% level, 95% of the values for all the controls fell between 96.8 and 568.7 ms for the corrected post-stimulatory pause, and between 114.5 and 434.3 ms for the corrected maximum return cycle. A study of the distribution zones of the graph CT/CR-AA/AA proved that an absent zone II is a pathological finding. In the group of sinus bradycardias the limits of what constitutes pathology are less clear, and the situation is not improved by noting whether atrial "echos" are present or absent. Because there is a narrow positive correlation between the values given by the two methods, the physio-pathology of sinus dysfunction can be discussed.

Bradycardia↗
PubMed1975

Evaluation of the antibiotic effect of treatment of maxillary sinusitis.

As the effect of antibiotic treatment of maxillary sinusitis has been questioned, the elimination of bacteria from sinus secretions was studied during antibiotic treatment. Penicillin V, azidocillin, tetracycline or doxycycline was administered to 54 patients with maxillary sinusitis. Samples of sinus secretion were aspirated both before treatment and 2-3 days after the onset of treatment. When the antibiotic concentration was below the upper limit of MIC for sensitivity group 1, bacterial growth was present in practically all samples. When the antibiotic concentration equalled or was above this limit, there was no bacterial growth in about half of the samples. A prerequisite for antibiotic effect--elimination of bacteria--is that the antibiotic concentration is well above the MIC of the bacteria at the site of infection. The choice between bactericidal or bacteriostatic antibiotics appeared unimportant. Bacterial survival in the maxillary sinus despite a high antibiotic concentration in the sinus illustrates that MIC values determined in the laboratory do not always mirror the sensitivity of bacteria to antibiotics in vivo.

Anti-Bacterial Agents↗
PubMed1976

[Misleading x-ray diagnosis due to maxillary sinus asymmetries (author's transl)].

Asymmetries of the maxillary sinus with partial or total radiographic opacity mislead to the diagnosis of chronic sinusitis. Using three radiographic standard projections, computerised planimetric analysis and cephalometric studies helped to explain radiological opacity in 26 patients. So called "mucosal thickening" may be due to varying development of the zygomatic recess. Total opacity was caused not only by unilateral volume difference exceeding 30%, but also by straightning of the first lateral line in basal views of small and moderate sized sinuses. Cephalometric analysis in maxillary sinus asymmetry revealed ipsilateral transversal underdevelopment of facial- and skullbone. Reduced pneumatisation of the ethmoid, spenoid, mastoid and frontal sinus in diminishing order was also ipsilateral. Using photostat analysis there was nevertheless no correlation between facial- and coexisting maxillary sinus asymmetry.

Cephalometry↗