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At least 19 recordsLinked to original sources
PubMed1986

A comparison of 111In-labelled polymer beads and 99mTc-Sn-colloid as solid food and semi-solid food tracers for scintigraphic gastric emptying studies.

In order to establish the efficacy of labelling a solid meal and a semi-solid meal with either 111In-labelled polymer beads or 99mTc-tin colloid beagle dogs were fed variously labelled meals of different consistencies and then monitored by scintigraphy for gastric motility patterns. The labelling with each tracer was either performed by thoroughly mixing it into the food before cooking, or alternatively by surface labelling after the food had been cooked. For the 99mTc-Sn-colloid tracer no difference was found in the measured gastric emptying times resulting from either pre-cooking labelling or surface labelling of the meals. Cooking the tracer together with the ingredients does however seem to promote a firm entrapment of the 111In-polymer beads into a solid protein, and in this manner the 111In-labelled resin appears to be a reliable solid food tracer. Surface labelling with 111In-polymer beads of a solid meal with a smooth texture fails totally and the tracer empties with the liquid phase.

Animals↗
PubMed2003

Eating and breathing: interactions between respiration and feeding on solid food.

Chewed solid food accumulates in the oropharynx prior to swallowing. The mechanism for preventing aspiration during this interval is unknown, but may be related to respiration. The purpose of this study was to determine how eating, especially bolus formation in the pharynx, affects respiration. We examined nasal air pressures, masseter electromyography (EMG), and videofluorography (VFG) of four normal young adults eating 8 g each of banana and cookie (two trials each food). Resting respiration was recorded for 30 s before eating. Respiratory cycles (RCs) were classified as prefeeding, feeding (excluding cycles with included swallows), and swallowing cycles. RC duration was greater for swallowing than for feeding and prefeeding RCs (P < 0.001). There were up to three swallows in a single RC, but the increase in swallowing RC duration was greater than swallow duration. Swallow apnea began before bolus transport through the hypopharynx and ended as the bolus tail entered the esophagus. There were semirhythmic perturbations in nasal air pressure associated with masseter activity during chewing, suggesting that there was oronasal airflow during jaw closing via the velopharyngeal isthmus. The most important finding was that bolus aggregation in the valleculae usually occurred during an extended plateau in nasal air pressure following active expiration. This suggests that aspiration during eating is prevented by inhibiting respiration during bolus formation in the oropharynx.

Adult↗
PubMed1989

Tongue movement in the cat during the intake of solid food.

During feeding, solid food in the mouth progresses towards the pharynx during transport cycles, but it does not do so in chewing cycles. In the cat, the two cycle types differ with respect to jaw and hyoid movement but it is not known if, or how, any differences in tongue movement arise. This study sought to quantify the tongue movements in the different cycle types. Radio-opaque markers were placed in the midline of the cat tongue. While the animals ate solid food, the marker movements (viewed in the sagittal plane) were recorded by cine-radiography. The movement of the tongue relative to the palate could be split into three components derived from (a) movement of the mandible, (b) movement of the hyoid, (c) movement produced within the body of the tongue itself. Although the differences in jaw movement between transport cycles and chewing cycles produced some differences in tongue movement relative to the palate, differences in the movements produced within the tongue itself were of greater significance. Transport cycles were characterized by rhythmic extensions of the tongue; the protracted tongue was about 60% longer than the retracted tongue. In chewing cycles, rhythmic length changes (viewed in the sagittal plane) were reduced and could be partly explained by an associated rotation of the tongue. In transport cycles the tongue, with food on it, was elevated to the palatal rugae as it extended, but when it shortened it was out of contact with the palate. It is suggested that these movements form the basis of a transport mechanism.

Animals↗
PubMed2003

Food protein-induced enterocolitis syndrome caused by solid food proteins.

BACKGROUND: Infantile food protein-induced enterocolitis syndrome (FPIES) is a severe, cell-mediated gastrointestinal food hypersensitivity typically provoked by cow's milk or soy. Solid foods are rarely considered a cause. OBJECTIVE: To describe the clinical characteristics and natural history of FPIES provoked by solid foods. METHODS: Patients with FPIES induced by solid foods were identified and their clinical course compared with a control group with FPIES caused by cow's milk and/or soy evaluated over the same time period. RESULTS: Fourteen infants with FPIES caused by grains (rice, oat, and barley), vegetables (sweet potato, squash, string beans, peas), or poultry (chicken and turkey) were identified. Symptoms were typical of classical FPIES with delayed (median: 2 hours) onset of vomiting, diarrhea, and lethargy/dehydration. Eleven infants (78%) reacted to >1 food protein, including 7 (50%) that reacted to >1 grain. Nine (64%) of all patients with solid food-FPIES also had cow's milk and/or soy-FPIES. Initial presentation was severe in 79% of the patients, prompting sepsis evaluations (57%) and hospitalization (64%) for dehydration or shock. The diagnosis of FPIES was delayed, after a median of 2 reactions (range: 2-5). Thirty patients with typical cow's milk- and/or soy-FPIES were identified for comparison. Overall, 48% of the 44 infants with FPIES were reactive to >1 food protein, and the risk for multiple food hypersensitivity approached 80% in the infants with solid food or soy-induced FPIES. None of the patients developed FPIES to maternally ingested foods while breastfeeding unless the causal food was fed directly to the infant. CONCLUSIONS: Cereals, vegetables, and poultry meats, typically regarded as of low allergenic potential, must be considered in the evaluation of FPIES, particularly in infants previously diagnosed with FPIES to cow's milk or soy, and as an initial cause in patients who have been exclusively breastfed. Infants with FPIES are at risk for multiple dietary protein hypersensitivities during an apparent period of immunologic susceptibility. Pediatricians should consider FPIES in the differential diagnosis of shock and sepsis.

Age Factors↗
PubMed2006

Food allergy and the introduction of solid foods to infants: a consensus document. Adverse Reactions to Foods Committee, American College of Allergy, Asthma and Immunology.

OBJECTIVE: To make recommendations based on a critical review of the evidence for the timing of the introduction of solid foods and its possible role in the development of food allergy. DATA SOURCES: MEDLINE searches using the following search algorithm: [weaning AND infant AND allergy]/[food allergy AND sensitization]/[dietary prevention AND food allergy OR allergens]/[Jan 1980-Feb 2006]. STUDY SELECTION: Using the authors' clinical experience and research expertise, 52 studies were retrieved that satisfied the following conditions: English language, journal impact factor above 1 or scientific society, expert, or institutional publication, and appraisable using the World Health Organization categories of evidence. RESULTS: Available information suggests that early introduction can increase the risk of food allergy, that avoidance of solids can prevent the development of specific food allergies, that some foods are more allergenic than others, and that some food allergies are more persistent than others. CONCLUSIONS: Pediatricians and allergists should cautiously individualize the introduction of solids into the infants' diet. With assessed risk of allergy, the optimal age for the introduction of selected supplemental foods should be 6 months, dairy products 12 months, hen's egg 24 months, and peanut, tree nuts, fish, and seafood at least 36 months. For all infants, complementary feeding can be introduced from the sixth month, and egg, peanut, tree nuts, fish, and seafood introduction require caution. Foods should be introduced one at a time in small amounts. Mixed foods containing various food allergens should not be given unless tolerance to every ingredient has been assessed.

Age Factors↗
PubMed1984

Gastric emptying and sieving of solid food and pancreatic and biliary secretions after solid meals in patients with nonresective ulcer surgery.

This study was undertaken to compare with previously published findings in normal subjects and subjects after truncal vagotomy and antrectomy the effects of nonresective ulcer surgery on (a) gastric emptying, grinding, and sieving of solid food and on (b) pancreatic and biliary secretions. Six subjects with proximal gastric vagotomy and 7 subjects with truncal vagotomy with pyloroplasty were studied using a previously validated indicator perfusion system with its aspiration port placed in the proximal jejunum. All subjects were given a meal of 30 g of 99mTc-liver, 60 g of beefsteak, and 100 ml of H2O. In conjunction with a gamma-camera to measure total gastric emptying of 99mTc-liver, this method allowed us to estimate the fraction of 99mTc-liver emptied from the stomach as particles of less than 1-mm diameter; in addition, we were able to measure jejunal concentrations and outputs of bile salts and pancreatic enzymes. In subjects with proximal gastric vagotomy, all parameters studied were indistinguishable from normal. Subjects with truncal vagotomy and pyloroplasty behaved similarly to subjects with vagotomy and antrectomy, showing (a) early precipitous emptying of food, (b) heterogeneous distribution of half-emptying times, (c) near normal concentration of biliary and pancreatic secretions, (d) markedly reduced jejunal flow rates, and (e) a reduction in postcibal trypsin secretion. In contrast to subjects after truncal vagotomy and antrectomy, however, the majority of subjects with vagotomy and pyloroplasty did not show a persistent defect in grinding and sieving of solid food.

Bile↗
PubMed2003

Selection of reference foods for a scale of standards for use in assessing the transitional process from milk to solid food in infants and pre-school children.

OBJECTIVE: This paper describes the development of a reliable scale of standards for use in evaluating the progress of the transition from milk to solid food in infants and preschool children. The maturation of chewing and swallowing behavior in infants and young children, which enables processing of solid food, varies, and a scale would assist not only in the instruction of mothers and nurses but also in preventing delay in the introduction of solid food. DESIGN: A range of 159 reference foods were selected on the basis of intake during the period of transition from liquid to solid food. These foods were listed in our previous study, Validity and reliability were tested to create a scale. METHODOLOGY: Foods were selected on the basis of 50% of the subjects studied being able to eat them, and on the food groups classified by cluster analyses using the Varclus procedure of SAS. Validity, of the scale was tested by using Pearson's correlation coefficient between the scale score of selected food items and the total score of all 159 food items. The total score of 159 food items was calculated using the general linear models (GLM) procedure of SAS. Reliability was tested using Cronbach's coefficient alpha. SETTING: Public health centers in Aomori, Tokyo, Saitama, Nagano, and Okinawa (Japan). SUBJECT: Five hundred and eighty healthy mothers and children from 2 to 46 months were randomly selected and 470 (81.0%) completed the study. To avoid regional bias, subjects were drawn from northern to southern prefectures in Japan, namely Aomori, Tokyo, Saitama, Nagano, and Okinawa. RESULTS: Twenty food items were selected. By analyzing the score correlation using Pearson's correlation coefficient (R =0.97, P <0.001) and GLM (R2 =0.95, P <0.001), it was confirmed that these 20 food items adequately represented the original 159. The reliability was also found to be sufficient (Cronbach's coefficient alpha=0.96). CONCLUSIONS: The findings demonstrate that a scale of standards for measuring progress in chewing ability can be created using 20 food items. Such a standard will provide a useful basis against which to assess delay of solid food introduction in childhood. SPONSORSHIP: Grant-in-Aid for Scientific Research, provided by the Japanese Ministry of Education, Science and Culture, Project No. 07838030.

Child, Preschool↗
PubMedDate not supplied

Infant feeding practices in Ottawa-Carleton: the introduction of solid foods.

Infant feeding guidelines regarding the introduction of solid foods are generally not well known in Canada. The guidelines recommend that solid foods be introduced between four to six months of age, depending on the developmental readiness of the infant. In order to understand the underlying factors and patterns which contribute to the introduction of solid foods in infants, data were analyzed from three cross-sectional surveys of parents of six-month-old infants from the Ottawa-Carleton region (n = 373, 1988; n = 330, 1992; n = 338, 1996) conducted by the Ottawa-Carleton Health Department. Multivariable analysis showed that mothers who: did not breastfeed, were younger, had lower education, smoked or had partners that smoked, and lacked support after birth, were more likely to introduce solid foods before four months of age. These data support the need for nutrition education programs to increase adherence to the new Nutrition for Healthy Term Infants guidelines.

Adult↗
PubMed1976

Factors influencing growth of rumen, liver, and other organs in kids weaned from milk replacers to solid foods.

From pooled data of many feeding trials with kids fed various types of solid foods from 37 days of age and slaughtered thereafter, relationships between such independent variables as age, cumulative intake of solid food, weight gain, and/or final body weight and such dependent variables as weights and such dependent variables as weights of stomach-compartments, heart, liver, kidneys, and spleen were analyzed. Growth of forestomachs, and especially rumen mucosa, relative to body weight was stimulated only in feeding periods of solid foods. Gain, intake of solid food, and final body weight were the best predictors for growth of forestomach-compartments, liver, and heart, respectively. Correlations were large between ruminoreticulum weight and liver weight and among weights of forestomach-compartments. Second degree polynomials were fitted to predict the curvilinear relationships between solid-food intake and either ruminoreticulum weight or rumen mucosal weight, and a linear equation was fitted to predict the relationship between solid-food intake and liver weight. Feeding of roughage increased rumen muscular and omasal weights. Growth of the rumen under stimulation of solid-food intake may be regulated by the same biological factors contributing to increased growth rate of the whole animal. In this situation, growth of the rumen may be correlated closely with growth of the liver.

Animal Feed↗
PubMed1985

Dietary manipulation of postprandial colonic lactose fermentation: I. Effect of solid foods in a meal.

The effect of adding solid foods--cornflakes, banana and hard-boiled egg--to a meal with 360 ml of intact milk containing 18 g of lactose was investigated in 13 lactose-malabsorbers and 10 lactose-absorbers chosen from 36 Guatemalan adults screened for their capacity to digest and absorb completely the lactose in this volume of milk. A six-hour hydrogen breath test was used as the index of carbohydrate absorption. Minimal breath H2 was excreted by lactose-absorbers with either the intact milk alone, the intact milk with solid foods, or lactose-prehydrolyzed milk with solids. In lactose-malabsorbers, however, the 6-h excretion of H2 with intact milk plus solid food was intermediary between milk alone and prehydrolyzed milk with solids. A relative net reduction of 47% in lactose malabsorption was produced by adding food, and the peak-rise in breath H2 was delayed by 2 hours. A physiological consequence of taking solid foods along with milk is a slower rate of colonic fermentation, and this may be the basis for reducing gastro-intestinal symptoms in lactose-intolerant malabsorbers.

Adult↗
PubMed1978

Diets in the first six months of infants in western Massachusetts. II. Semi-solid foods.

The early introduction of solid foods was observed in three ethnic and income groups in a survey of 268 infants in western Massachusetts. By four weeks of age, cereal had been introduced into the diets of 57 per cent and fruit to 32 per cent of the infants. Patterns of introducing and feeding solid foods to breast-and formula-fed infants were similar and were related more to income than to type of milk fed. The cost of infant feeding can draw heavily on the family's food budget.

Black or African American↗
PubMed1977

[The measurement of gastric emptying of solid food. Comparison of 2 solid phases by means of double isotope technic].

The suitability of a simple method of measuring the rate of gastric emptying of solids using 99mTc-marked filter paper pieces has been evaluated. In five healthy volunteers emptying of the filter paper pieces and of 198Au-tagged liver was measured simultaneously. In every proband the filter pieces left the stomach at a faster rate than the liver, but showed a linear emptying pattern in each experiment. Based on these observations and on recent results of other authors, a new concept of the gastric emptying of solids is presented. Within the framework of this model the use of the filter pieces in clinical studies to simulate a solid meal appears to be justified.

Gastrointestinal Motility↗
PubMed1985

Rats (Rattus norvegicus) do not prefer salted solid food.

Many studies have demonstrated that when sodium-replete rats are given a choice between water and isotonic saline, they consume more of the isotonic saline. Their ingestive responses to a choice between salted and unsalted food, however, have not been studied in the same detail. Because humans consume salt in or on food rather than in pure water, this lack of information calls into question the use of the rat as the animal model for human excess salt consumption. In Experiment 1, 16 Sprague-Dawley rats were given 1-hr access to salted and unsalted foods (potato chips, peanuts, soup) commonly consumed by humans in the salted form. In each choice situation, rats consumed more of the unsalted variety of solid food. In Experiment 2, the concentration of salt in a wider variety of foods was varied. Fifteen rats were allowed a choice of a given salt concentration or the unsalted food. In no case was the salted solid food eaten in excess of the unsalted solid food, and in general, more of the unsalted solid food was eaten. In a third experiment, two groups of 8 rats were given exposure from weaning to either salted or unsalted potato chips. Three-months of exposure to salted chips or unsalted chips did not alter the rats' relative intake of salted chips. When given a choice, more unsalted chips were consumed by both groups. These experiments indicate that sodium-replete Sprague-Dawley rats generally prefer unsalted solid foods to salted ones.

Animals↗
PubMed1994

Early solid food diet and eczema in childhood: a 10-year longitudinal study.

The relationship between early solid feeding in the first four months and risks of eczema in childhood was examined in a birth cohort of 1265 children studied to the age of 10 years. The major findings of this analysis were: 1) children exposed to a diverse solid food diet during their first four months had risks of eczema in early childhood which were about 1.6 times those of children who were not introduced to solid food by age four months. These associations persisted when a range of confounding factors (including family history of atopic disease, infant milk diet (breast/bottle) and family social background factors) were taken into account. 2) Similar associations between early infant diet and risks of chronic and recurrent eczema up to the age of ten years were also found. It was estimated that after adjustment for confounding factors, children exposed to an early diverse solid food diet had risks of eczema which were over 2.5 times those of children not introduced to solid feeding. These results are generally consistent with the hypothesis that early exposure to a diverse solid food diet may increase risks of eczema in children who are susceptible to this condition.

Age Factors↗
PubMed1976

99mTc-tagged chicken liver as a marker of solid food in the human stomach.

Past measurement of gastric emptying of solid food in man has depended on external counting of surface-absorbed isotopes without verification that isotopic labels remain attached to solid food in the stomach. In this study chicken liver was isotopically labeled with 99mTc incorporated uniformly and intracellularly throughout the liver substance. In vitro studies showed less than 10% loss of 99mTc from liver incubated with pepsin HC1. By contrast, up to 90% of 51Cr absorbed to scrambled eggs became detached under similar conditions. In feeding experiments less than 10% of 99mTc was liberated from fed 99mTc liver, while significantly more 51Cr became detached from egg under identical intragastric conditions. We conclude that 99mTc-tagged chicken liver is an adequate marker of the rate of emptying of solid food and appears to be more reliable than 51Cr-labeled scrambled eggs from which 51Cr dissociates in the stomach.

Animals↗
PubMed1998

Eating habits of young children with Down syndrome in The Netherlands: adequate nutrient intakes but delayed introduction of solid food.

OBJECTIVES: To investigate nutritional status, pattern of being breast-fed, age at introduction of solid food, and adequacy of energy and nutrient intakes in children with Down syndrome in The Netherlands. DESIGN: Nutritional status was assessed by height and weight measurements. The dietary history method was used to collect information on the diet. Data obtained from children with Down syndrome were compared with data from control subjects and from the general population of Dutch children. Adequacy of energy and nutrient intakes was assessed by comparison to US recommendations. SUBJECTS: Forty-four Dutch children with Down syndrome (newborns to 4-year-olds) and 37 healthy control subjects without this syndrome. STATISTICAL ANALYSES: The prevalence of breast-feeding of children with and without Down syndrome was compared using the chi 2 test. To compare ages at which solid food was introduced, the log-rank test and Kaplan-Meier curves were used. Anthropometric data and mean dietary intake were compared between the groups using 2-way analysis of variance. Comparison to recommended levels of dietary intake was performed using 95% confidence intervals. RESULTS: Heights and weights of the children with Down syndrome were in the normal range. Down syndrome does not affect the prevalence of breast-feeding of children or the adequacy of their energy and nutrient intakes, but it does significantly delay the age at which solid food is introduced, which can be deleterious to oral-motor development. APPLICATION: If late introduction of solid food is observed in children with Down syndrome, pre-speech therapy should be considered.

Age Factors↗