Urinary excretion kinetics for evaluation of drug absorption. IV. Studies with tetracycline absorption enhancement factors.
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Results for “TETRACYCLINE/metabolism”
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Influence of dissolution rate and surface on tetracycline absorption.
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Urinary excretion kinetics for evaluation of drug absorption. II. Constant, rate-limited release of tetracycline after ingestion by humans.
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Tetracycline: studies on absorption, distribution, excretion, and clinical trial in children.
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Fluorescence of tetracyclines in bone. Absorption maximum, hydration shell and polarization effects.
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Radioactive 7-iodo-6-deoxy-tetracycline in tumour tissue.
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Fluorescence of tetracyclines in bone tumours, normal bone and teeth.
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Tetracyclines in human dentine.
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Excretion of demethylchlortetracycline into the bile.
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Bile↗
Serum levels of antibiotics in young and old subjects following administration of dihydrostreptomycin and tetracycline.
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The cerebral uptake of tritiated tetracycline from blood and cerebrospinal fluid under normal conditions and in experimental pneumococcal meningitis.
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Studies on renal excretion of tetracycline.
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TETRACYCLINE fluorescence of body tissues and tumor tissues.
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Selective localization of tetracycline in mitochondria of living cells.
The property of tetracycline to induce fluorescence has been used to determine its localization in living cells. It was found that this antibiotic, as well as the related antibiotics oxytetracycline and chlorotetracycline, specifically combines with the mitochondria of living cells, either in tissue culture or in fresh preparations from various organs.
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Chlorination inhibitors affecting the biosynthesis of tetracycline.
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Production of tetracycline by Streptomyces aureofaciens in synthetic media.
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Biosynthesis of tetracycline by 5-hydroxy-tetracycline-producing cultures of Streptomyces rimosus.
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Skeletal pigmentation due to tetracycline.
Two cases of pigmentation of the skeletal system due to tetracycline are reported. It is suggested that tetracycline may be stored in bone due to a tetracycline hydrochloride calcium phosphate complex after prolonged tetracycline administration, and that tetracycline may be the antibiotic of choice in certain cases of osteomyelitis. Dark pigmentation of the teeth may be due to prolonged tetracycline therapy and may be the only sign of heavy deposition into the skeletal system.
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