The effect of thiopental sodium and pentylenetetrazole on the cortical and subcortical response to photic stimulation in the cat.
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Local tetanus was induced in rabbits by the intramuscular injection of tetanus toxin. The relative potency of drugs which abolished the muscle spasm was determined using quantitative electromyography and the accuracy of the method tested with mephenesin and thiopentone. It is suggested that the method is suitable for screening new drugs for clinical use.
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