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At least 19 recordsLinked to original sources

PubMed1985

Thyroglossal tract anomalies.

Thyroglossal tract anomalies present most frequently before the second decade of life. Investigations should include ultrasound and thyroid isotope scan to demonstrate the presence of other functioning thyroid tissue prior to excision. Cysts demonstrating echogenic material centrally should be considered to be inflamed and surgical exploration carried out under antibiotic cover to minimize postoperative infection. Total excision of the thyroglossal tract anomaly must include the body of the hyoid bone to prevent recurrence and reduce the risk of further symptoms.

Adolescent↗

PubMed1999

Papillary thyroid adenocarcinoma arising in a thyroglossal tract remnant following excision of a thyroglossal cyst: the importance of the Sistrunk procedure.

Carcinoma of the thyroglossal tract is a rarity--over the past 85 years only 160 cases have been reported. We report the first case of carcinoma arising in a thyroglossal tract remnant 10 years after simple excision of a thyroglossal cyst. This case highlights the importance of the Sistrunk procedure, (the removal of the entire thyroglossal tract) for preventing not only cyst recurrence, sinus and fistula formation, but also the occurrence of carcinoma.

Adenocarcinoma↗

PubMed2002

Auto-immune thyroiditis presenting as a thyroglossal tract swelling.

Both thyroglossal cysts and aberrant thyroid tissue may present as a mid-line neck swelling. We report a case of autoimmune thyroiditis presenting as a thyroglossal swelling in a middle-aged woman. This very rare finding is discussed with reference to the optimal management of thyroglossal tract swellings.

Diagnosis, Differential↗

PubMed1978

Thyroglossal-tract cyst.

Thyroglossal-tract cyst should be included in the differential diagnosis of any mass found in the anterior midline of the neck. A discussion and review of forty-two cases diagnosed between 1970 and 1976 at Wilford Hall USAF Medical Center are presented.

Adolescent↗

PubMed2000

Morphology of the human thyroglossal tract: a histologic and macroscopic study in infants and children.

The anatomic development of thyroglossal tract remnants is not understood at present. For analysis of morphology and growth patterns of thyroglossal tract remnants, we used histologic whole organ serial sections to determine developmental changes through the first years of life. Larynges of 58 infants and children ages 1 month to 13 years were obtained in whole organ serial step-sections in an axial plane. The slides were stained with hematoxylin and eosin, Alcian blue, and periodic acid-Schiff stains. Altogether, 3,247 histologic slices were examined. The resulting data were then correlated with the age and sex of the specimens. We found, in 24 cases (41.3%), remnants of the thyroglossal tract or ectopic thyroid tissue. In 4 specimens (16.6%), a complete thyroglossal tract could be observed that presented a ventral path in relation to the hyoid bone with no contact with the perichondrium of the cartilage. Hormonal activity of ectopic thyroid tissue was proven in 20 cases (34.5%). Thyroid follicles were located in 2 cases (3.5%) in the hyoid bone. The thyroglossal ducts revealed a modest tendency for a left-sided pathway, whereas thyroid follicles were located more on the right paramedian side. Morphometric data on the development and structure of the thyroglossal tract and the thyroid follicles during infancy and childhood are presented. The study provides quantitative data of clinical interest that elucidate the anatomy of thyroglossal tract remnants. In addition, our investigation supports Sistrunk's operative approach for avoiding recurrences in the treatment of thyroglossal duct cysts.

Age Distribution↗

PubMed1977

The applied anatomy of thyroglossal tract remnants.

Recurrences after surgery for thyroglossal cysts and fistulas were common until, in 1920, Sistrunk described his technique for removing the whole thyroglossal tract. Since that time there has been considerable argument concerning the exact path taken by the tract particularly in relation to the hyoid bone. In an attempt to elucidate this problem, studies have been made of embryos at varying stages of development, of serially step-sectioned adult larynges and of surgical specimens. These studies suggest that the thyroglossal tract occupies a constant and embryologically predictable position in relation to the hyoid bone and they support the rationale of Sistrunk's procedure.

Female↗

PubMed1993

[Neoplastic transformation of a cyst in the thyroglossal tract. Apropos of a case].

Cancers of the thyroglossal tract are very rare. Seventy-four patients with a cyst of the thyroglossal tract were operated in our hospital between 1978 and 1991. A papillary carcinoma was discovered on histological examination in one case. This cancer was treated by Sistrunk's operation. The patient had no sign of recurrence one five years after the operation. This paper presents the case report of this unusual cancer of which fewer than 100 similar cases have been reported in the literature.

Adult↗

PubMed1979

Radiologic findings in persistent thyroglossal tract fistulas.

Recurrent cysts and persistent fistulas are frequent complications of thyroglossal cystectomy if the excision is not extended through the hyoid bone to the foramen cecum. In 3 cases of persistent thyroglossal tracts, fistulography was performed and found to be valuable in demonstrating the extent of the tract. Surgical excision was completed and specimens were examined histologically. The retained upper portion of the thyroglossal tract was the established cause of the recurrent symptoms; removal of the entire tract up to the foramen cecum was confirmed as the recommended procedure.

Adult↗

PubMed2003

Management of thyroglossal tract disease after failed Sistrunk's procedure.

Sistrunk's procedure for thyroglossal duct remnants has a very high success rate, there remains the occasional patient, however, that will have recurrent disease despite a competently performed operation. Applied anatomy and embryology proffer a solution to this problem. Extending the Sistrunk operation, with an anterior wide local excision remaining within normal tissue, enables removal of the entire thyroglossal tract remnant. A retrospective case note review was conducted to study our experience using this extended procedure to treat patients with thyroglossal tract disease that had recurred after a previous Sistrunk's operation. Six patients aged from five to 33 years were included in the study. There was one recurrence and the complication rate was comparable to the standard operation. It was concluded that a wide local excision is a valuable extension of the Sistrunk operation for the management of recurrent disease.

Adult↗

PubMed2001

Histological characterization of the thyroglossal tract: implications for surgical management.

OBJECTIVES: In the current report, we characterized the relationship between the central hyoid bone and the thyroglossal tract and determined the prevalence of ectopic thyroid follicles in the adjacent soft tissues. STUDY DESIGN: Retrospective pathological analysis. METHODS: The resected specimens from 104 patients who underwent a modified Sistrunk procedure with wide-field dissection were retrospectively analyzed. Under light microscopy, serial sections were examined to determine whether the thyroglossal tract passed anterior to, posterior to, or within the hyoid bone. Specimens were also examined for the presence of thyroid follicles in the periductal and pericystic soft tissues. RESULTS: In 50 cases (48%), the tract position in relation to the hyoid bone could not be identified secondary to extensive arborization, marked inflammation, specimen fragmentation or a combination of these. Thyroid follicles were observed in 9 (18%) of these specimens. In the remaining 54 cases (52%) the tract was located anterior to the central arch of the hyoid bone in 39 (72%) and posterior to it in 15 (28%). Thyroid tissue was observed in 46% of specimens (P =.004), regardless of whether the tract was anterior or posterior. CONCLUSIONS: These results demonstrate that tract position often cannot be defined, but when a portion is dominant, it is likely to be anterior to the hyoid bone. Ectopic thyroid tissue can be found in almost 50% of specimens when the tract position is identifiable. With appropriate surgical management, a recurrence rate of less than 4% can be expected, despite the presence of ductule multiplicity, marked inflammation, tract position posterior to the hyoid bone, and ectopic thyroid follicles.

Choristoma↗

PubMed1991

[Cancer arising in a cyst of the thyroglossal tract].

Two new cases of thyroglossal cyst carcinoma are reported. Such cancers concern rather young women. The diagnosis must be suspected whenever a thyroglossal cyst is associated with cervical adenopathies. The most performing investigation seems to be fine-needle aspiration guided by echography. The malignant diagnosis is made during surgery by frozen section of the lesion, confirmed by histology. Two type of cancer must be distinguished: squamous cell carcinoma and carcinoma of thyroid type. The management of squamous cell carcinoma includes a large resection. For thyroid type carcinomas, total thyroidectomy and bilateral neck dissection are to be considered. Because of up-to-date insufficiency following, it is difficult to make a prognosis.

Adolescent↗

PubMed1950