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[The quantitative composition of natural and technologically changed aromas of plants. II. Aroma compounds in oranges and their changes during juice processing (author's transl)].

After enzyme inhibition with methanol the original volatile compounds of the fruits were investigated in order to compare the quantitative composition of the aroma substances in orange fruits and juices. Aroma compounds of fresh, flash pasteurized and pasteurized juices were analysed. After aroma enrichment by liquid-liquid extraction, prefractionation of the flavor compounds by column chromatography on silicagel 56 flavor substances in the fruits and in the different juices were identified and determined by gas chromatography and mass spectrometry. In comparison to their content in the fruits only 10% of the terpenic hydrocarbons and about 30-66% of the esters were found on average in the fruits. Among the secondary flavor substances, which were not present or present only in traces in the fruits, but showed in juices concentrations up to 0,2 ppm, were 4-terpinenol, carveol and tr-2,8-menthadien-1-ol. After a thermic treatment also 3-hydroxy-2-butanone and 3-methyl-2-buten-1-ol were identified.

Acetoin↗

[The quantitative composition of natural and technologically changed aromas of plants. IV. Enzymic and thermal reaction products formed during the processing of tomatoes (author's transl)].

After the qualitative and quantitative investigation of the flavor compounds of tomatoes, the flavor compositions of tomato juices treated by different technological methods were determined. 80 aroma components were identified by gas chromatography and mass spectrometry. The quantitative comparisons showed that during the processing of juices unsaturated fatty acids acted as precursors for a series of C6-compounds, especially 1-hexanol, and cis-3-hexen-1-ol and that on the other hand some aroma compounds derived from carotenoid like structures, e.g. 6-methyl-5-hepten-2-one, geranyl- and farnesylacetone and beta-ionone were formed. As reaction products of thermal treatments among other increased amounts of acetoin, furfural, 5-methylfurfural and 6-methyl-5-hepten-2-one were established. The distribution of the aroma compounds dissolved in the serum or bound on the pulp was determined quantitatively by employing gaschromatographical methods.

Carotenoids↗

World blindness and the medical profession: conflicting medical cultures and the ethical dilemmas of helping.

This is an account of a thwarted humanitarian effort and the strategic and ethical issues that is raised. Between 14 and 17 million people in the world are blind with cataract, a condition readily corrected by surgery. In 1989 a proposal was developed to attack this problem by supplying volunteer ophthalmologists to the world's leading private voluntary organizations that carry out programs in less developed countries. The proposal was rejected. This article describes the proposal and the issues on which it foundered: cost effectiveness, appropriate technology, changing ideologies of assistance, and conflict between the cultures of medicine and public health. The account illustrates the far-flung consequences of technological change in medicine, as well as the practical and ethical questions facing organizations that carry out overseas assistance programs.

Altruism↗

Communications: the driving force behind the accelerating rate of change.

The rate of change of all aspects of the life of mankind on this planet is accelerating at an ever-increasing pace. It is stated that this upheaval is directly attributable to technological changes and their interaction with social, economic and political changes. The hypothesis is advanced that this dramatically increasing rate of change is due to four unique innovations, all dealing with communications. The four are the spoken language, the written language, the printing press and the electronic computer. The accelerating rate of technological change is measured by the rate at which one hundred "technological breakthroughs" have appeared. In prehistoric times, such breakthroughs occurred tens or hundreds of thousands of years apart. Today, several appear each decade. Hope is expressed that this rapidly accelerating rate of change will enable mankind to cope with the major problems of our modern civilization. The problems specifically flagged out are population growth, human genetics, energy and pollution.

Communication↗

Critical assessment of prostate cancer staging.

Staging of prostatic adenocarcinoma is a systematic classification of the extent of disease based on clinical and pathologic criteria. This classification determines treatment and reflects ultimate expected clinical outcome. The technologic changes in diagnostic modalities need to be incorporated into the staging classification and a better assessment of biologic hazard of each individual tumor needs to be developed to further refine current treatment of prostate cancer.

Acid Phosphatase↗

(Re)imagining the Future of Genetic Counseling: A Reflexive Qualitative Analysis of Sociopolitical Power, Cultural Safety, Systemic Racism, and Comparative Practice in the United Kingdom, Aotearoa New Zealand and, Australia.

Genetic counseling is undergoing a rapid transformation as genomic medicine becomes embedded within mainstream healthcare systems. At the same time, the profession is being challenged to respond to systemic racism, colonial legacies, technological change, and evolving expectations regarding equity and justice. Historically, genetic counseling emerged within twentieth-century medical genetics and was influenced by political, social, scientific, and medical forces that included eugenic ideology, values, and practices. The profession has since evolved substantially toward psychosocial, patient-centered, and non-directive models of care. Contemporary debates regarding "newgenics" or "neugenics" further demonstrate how concerns regarding equity, reproductive ethics, disability, and genomic stratification continue to shape genomic healthcare discourse. This qualitative reflexive practice paper explores how systemic racism, colonial legacy, cultural safety and structural power shape genetic counseling practice in the United Kingdom (UK), Aotearoa New Zealand and Australia, and how these forces continue to reshape the profession's future identity. A reflexive, narrative, and comparative qualitative approach was employed, grounded in the authors' lived professional experiences across UK and Australasian contexts and informed by purposively selected policy, professional and scholarly literature relating to cultural safety, dignity, anti-racism, and Human Rights-Based Decision-Making. Through iterative reflexive dialogue, comparative analysis, and thematic synthesis, four interrelated themes were developed examining sociopolitical context, systemic racism, cultural safety and technologization within contemporary genetic counseling practice. Comparative analysis identified substantial differences in how culturally responsive practice is conceptualized and operationalized across settings. In Aotearoa, cultural safety is strongly shaped by Te Tiriti o Waitangi, bicultural accountability, and Māori sovereignty frameworks. In Australia, culturally safer genomic care has increasingly developed through Indigenous-led initiatives and workforce reform, including the Australian Alliance for Indigenous Genomics (ALIGN). In contrast, UK practice remains largely situated within equality, diversity, and inclusion (EDI) frameworks that may insufficiently address systemic racism and structural power within increasingly diverse populations. Reflexive clinical examples demonstrated how inequities may emerge through undocumented patient values, standardized pathways, assumptions regarding autonomy, and misinterpretation of culturally specific communication styles. Re-imagining the future of genetic counseling requires more than just technological advancement. It requires reflexive engagement with dignity, inequity, and the sociopolitical realities of the populations served. These insights re-imagine a culturally grounded, socially responsive future for genetic counseling in an era shaped by genomic mainstreaming, digital transformation, artificial intelligence and workforce reform and one in which the profession remains ethically anchored, relationally attuned, and committed to justice-oriented practice.

Humans↗

Suspended judgment. AIDS and the ethics of clinical trials: learning the right lessons.

There is a tribe of thinkers who believe that new technological advances and scientific discoveries raise new ethical issues. And it is the case, of course, that scientific and technological change--change in knowledge and power--implies a new realm for choice and, therefore, moral reflection. In the case presently concerning us, they see the AIDS social and scientific crisis as requiring the adoption of new ethical principles. I believe to the contrary. AIDS--more broadly, the entire spectrum of HIV disease--does not in itself present radically new issues at the level of principle. For example, the questions associated with confidentiality and HIV disease that have to this point dominated public discourse about morality and AIDS simply resurrect old questions raised by potentially deadly infectious disease. Recent discussions of the ethical issues associated with HIV-infectious health care workers fail to recognize that HIV is simply a new garb for the old question of the impaired or unsafe practitioner. HIV disease does have this effect on ethical reflection, however: It rubs our noses in issues that may have received insufficient attention to date. The urgency and poignancy associated with moral conflict and HIV disease forces us to face up to questions hitherto ignored. But this may be a good or a bd thing. In the heat of crisis, being human, we are likely to call for change without adequate consideration of the need for and effects of that change.(ABSTRACT TRUNCATED AT 250 WORDS)

Acquired Immunodeficiency Syndrome↗

Indigenous body image amid rapid social and economic change: A reflexive thematic analysis of Wayuu narratives.

The Wayuu, Colombia's largest Indigenous group, are experiencing rapid social, economic, and technological change, including expanding internet access, educational opportunities, and increasing exposure to globalised media. Though the harmful effects of appearance-idealised media imagery on body image are well documented, indigenous body image research remains unevenly distributed across global contexts, with Latin American Indigenous communities particularly underrepresented. This study explored how Wayuu people understand and experience appearance ideals and body image in the context of expanding digital media exposure and rapid sociocultural and economic change. Five focus groups of up to 9 participants were conducted with 29 Wayuu participants (18-68 years; 23 women, 6 men). Using reflexive thematic analysis, three overarching themes were identified: (1) Intersecting sources of appearance pressure: encompassing influences from social media, Wayuu family expectations, and discrimination from non-Indigenous peers; (2) Negotiating and resisting appearance ideals: from body dissatisfaction and restrictive eating to affirmation of cultural identity as protection; and (3) The changing role of appearance in today's Wayuu culture: participants linked globalised appearance ideals to expanding educational opportunities, migration, digital connectivity, and broader socioeconomic transformations occurring within Wayuu territories. While exposure to global ideals fostered comparison and dissatisfaction, cultural pride and collective belonging appeared to buffer against internalised colonial values. Culturally grounded media literacy and education initiatives co-developed with Wayuu communities could foster critical reflection while strengthening heritage. These results highlight the need for decolonial, community-based approaches to body image research and intervention in Indigenous contexts.

Adolescent↗

Trace elements and health: an overview.

Trace element deficiencies, toxicities and imbalances in man are more difficult to relate to geochemical factors than they are in farm animals. The reasons for this are discussed and examples of such differences between man and grazing animals presented. The most convincing evidence of a geochemical causal link with human disease comes from the incidence and distribution of endemic goitre. The influence of technological developments upon this relation is discussed. Other associations between the physical environment, including the air and drinking water, and to health are given and critically examined in relation to the criteria necessary to distinguish between association and causation. The nature and extent of man-made modifications of the natural geochemical environment through technological change are discussed in relation to intakes of Fe, I, Zn, Pb and Se and their relation, in turn, to human health and disease. The currently proposed permissible limits or maximum tolerances of potentially toxic elements are presented, and the importance to these tolerances of the chemical and physical forms of the element and their metabolic interactions with other elements is emphasized.

Agriculture↗

People and work: some contemporary issues.

In advanced industrial societies social, economic, and technological changes are accompanied by changing values and attitudes to work, symptomatic of what some see as the transition to a post-industrial era. As a result existing job definitions and traditional forms of organization are being challenged and attempts made to restructure work so that it becomes meaningful and rewarding in the fullest sense, to the individual, to the enterprise, and to society. These range from programmes of job enlargement and job enrichment, within the framework of existing technologies, to experiments in the design of organizations as a whole in which fewer constraints are accepted as given. They entail and require a multidisciplinary approach as well as awareness of and commitment to the underlying values. The possibilities and benefits of restructuring work in these various ways have been demonstrated sufficiently to encourage interest at governmental level as well as by employers and trade unions. There are, however, no simple prescriptions or principles of universal application. Knowledge is still tentative and partial but there is consensus that the search for new ways of dealing with the organization of work and the allocation of resources is of fundamental importance.

Authoritarianism↗

Acupuncture-like stimulation with codetron for rehabilitation of patients with chronic pain syndrome and osteoarthritis.

Acupuncture is one of the oldest healing methods which is used in traditional medicine. In the modern medicine, we are witnessing a renaissance of this ancient treatment applied mainly in the management of chronic pain. A number of modern technological changes are being applied to replace, or modify, the classical needle treatment. Among many modalities used today is the novel addition in Transcutaneous Electrical Nerve Stimulation (TENS) called CODETRON which delivers acupuncture-like stimulation in a random order. CODETRON was developed by a Canadian Scientist and had been evaluated in a clinical trial in a multidisciplinary pain clinic on patients who came for acupuncture therapy over a period of two years. Indications, effectiveness and experiences with this form of treatment are presented. In addition, results obtained from a six week double-blind randomized placebo controlled pilot trial of osteoarthritis of the hip/knee with CODETRON which was conducted later. The results were highly suggestive of the beneficial effect of this nonhabituating mode of therapy and confirmed our initial uncontrolled trial results.

Acupuncture Points↗

Polycyclic aromatic hydrocarbon pollution from the aluminium industry.

Polycyclic aromatic hydrocarbons, the major air pollutants emitted by two aluminum reduction plants in Hungary, were measured in the emission dusts and in air particulates in nearby residential areas. There was a higher amount of PAHs in the emission dust of the plant operating with vertical stud anodes (plant "A") compared to the plant operating with horizontal stud anodes (plant "B"). PAHs in ambient air in the town, close to plant "A", were similar to the levels in emission dust, indicating a health hazard for the population. This is strengthened by the non-seasonal variation of benzo(a)pyrene content of ambient air in the town. Measurements of PAHs in the vicinity of the plant "B" and in a town 4 km away clearly showed a decrease in the concentration of the hazardous chemicals. Analysis of emission dusts from the power plant, close to plant "B", showed that 100-fold less PAHs are emitted compared with the plant. Although major technological changes cannot be made, improved emission control would be beneficial to the general population in that area.

Air Pollutants↗

Materials and techniques in fixed prosthodontics.

If we have learned anything from our experiences with all-ceramic systems such as Cerestore, Cerapearl, and even Dicor, it is that it takes years to uncover the strengths, weaknesses, and limitations of new materials and technologies. Manufacturers' initial claims for fit, strength, esthetics, biocompatibility, wear characteristics, and clinical performance should be viewed as preliminary until supported by independent laboratory and clinical studies. Laboratory testing alone may not provide sufficient insight into the relative strengths and weaknesses of products or assure comparable performance in the commercial dental laboratory or the ultimate testing arena, the oral environment. Moreover, the diversity of the new materials and techniques discussed demonstrates the breadth and depth of the technologic changes in dental biomaterials. The rate at which these dental products enter the marketplace and their sheer number alone are indeed staggering. Furthermore, these advances are not emerging from any single nation but from manufacturers all around the world (Japan, Germany, as well as the United States), indicating our international reliance on one another. Clearly, the decade of the 1990s is emerging as an exciting period in the development of biomaterials in comprehensive fixed prosthodontics and dentistry in general.

Calcium Sulfate↗

Occupational health hazards resulting from elevated work rate situations.

Some occupational health hazards resulting from an elevated rate of work due to recent mechanization and automatization are discussed on the basis of results of health examinations. A rapid increase of a cervicobrachial disorder among young cash register and packing machine operators has been observed. Switching to the use of electronic cash registers has been shown to have only limited efficacy due to increased operation speed, and high-speed complex finger and hand movements of packer operators have also proven to be as hazardous as key-board operations. The high incidence of low-back pain, in particular gradually developing pain, among workers in electric power supply work has been suggested to be the result of quick and intensified work to meet increasing supply demand. Likewise, the workload of electric locomotive and bullet train drivers has increased in accordance with increased train speeds, and has been shown to have had significant effects on their health particularly in regards to neural strain, intra-cab environment such as air pressure change, vibration, and noise, and rotation on irregular shifts. New steps seem required therefore to meet the new health problems arising from a combination of modern technological changes and elevated working speeds.

Atmospheric Pressure↗

Healthy family functioning: a cross-cultural appraisal.

It is increasingly recognized that rapid cultural, social, economic, and technological changes are imposing increasing stress on family structures, traditional values, and the ability to adapt to new environments in different societies. For the purposes of this paper, "healthy family functioning" is defined in terms of a family unit (however it is conceived in any given culture) effectively coping with cultural, environmental, psychosocial, and socioeconomic stresses throughout the family life cycle. While a review of international literature in the behavioural and biomedical sciences yields little data on comparative studies, there is growing awareness of the need for cooperative international research on family coping mechanisms and determinants of self-reliant communal coping behaviour, as well as more efficient utilization of already available knowledge. After consideration of methodological pitfalls of assessment procedures, there is a presentation of an evolving theory of healthy family functioning with the suggestion that studies of young married couples constitute a particularly promising vehicle for developing needed cooperative cross-cultural research.

Cross-Cultural Comparison↗