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At least 19 recordsLinked to original sources
PubMed1976

Uptake of the mosquito larvicide Temefos by the salt marsh snail, New Jersey--1973-1974.

Uptake of the mosquito larvicide temefos (Abate) by the salt march snail (Melampus bidentatus Say) in New Jersey was measured by gas-chromatographic analysis. Measurable quantities of temefos were found in the snails within 1 day after the first treatment with a 2% granular formulation but 3 weeks elapsed before uptake occurred following treatment with a temefos emulsion. Residues in the snails exposed to the granular formulation were generally more than 10 times higher than those in snails exposed to the emulsion although application rates of the granular formulation were only about three times higher than those of the emulsion. Residues in snails exposed to the emulsion fell below detectable levels less than 3 weeks after cessation of treatments although measurable amounts were found in snails exposed to the granular formulation for more than 5 weeks after the last treatment. The persistence of temefos in M. bidentatus suggests the potential for its movement through food webs exposed to the granular formulation.

Animals↗
PubMed1976

Storage and analysis of samples of water, fish, and mud from environments contaminated with abate.

Methods for extraction, cleanup, and analysis of samples of water, mud, and fish containing trace quantities of Abate have been developed. Water was extracted by high-speed stirring of 10 ml of hexane in a 300-ml sample. The extracts were evaporated and analyzed by gas chromatography with a limit of detection of 0.00003 ppm. Dried mud samples were extracted by shaking with acetone. An aliquot of the acetone extract was diluted with water and the Abate extracted into 10 ml of hexane by high-speed stirring. The extracts were analyzed by gas chromatography. Fish were extracted with methylene chloride, cleaned up on a silica gel column, and analyzed by gas chromatography. The limit of sensitivity of the methods for mud and fish was found to be 0.001 ppm. Fish samples were stored for 3 weeks in 10% formalin containing 5% sodium thiosulfate without significant loss of Abate residues. A biological magnification of greater than 100 was observed in fish exposed to Abate for 16 hr at concentrations of 0.02 and 0.002 ppm.

Animals↗
PubMed2022

Expansive and Diverse Phenotypic Landscape of Field Aedes aegypti (Diptera: Culicidae) Larvae with Differential Susceptibility to Temephos: Beyond Metabolic Detoxification.

Arboviruses including dengue, Zika, and chikungunya are amongst the most significant public health concerns worldwide. Arbovirus control relies on the use of insecticides to control the vector mosquito Aedes aegypti (Linnaeus), the success of which is threatened by widespread insecticide resistance. The work presented here profiled the gene expression of Ae. aegypti larvae from field populations of Ae. aegypti with differential susceptibility to temephos originating from two Colombian urban locations, Bello and Cúcuta, previously reported to have distinctive disease incidence, socioeconomics, and climate. We demonstrated that an exclusive field-to-lab (Ae. aegypti strain New Orleans) comparison generates an over estimation of differential gene expression (DGE) and that the inclusion of a geographically relevant field control yields a more discrete, and likely, more specific set of genes. The composition of the obtained DGE profiles is varied, with commonly reported resistance associated genes including detoxifying enzymes having only a small representation. We identify cuticle biosynthesis, ion exchange homeostasis, an extensive number of long noncoding RNAs, and chromatin modelling among the differentially expressed genes in field resistant Ae. aegypti larvae. It was also shown that temephos resistant larvae undertake further gene expression responses when temporarily exposed to temephos. The results from the sampling triangulation approach here contribute a discrete DGE profiling with reduced noise that permitted the observation of a greater gene diversity, increasing the number of potential targets for the control of insecticide resistant mosquitoes and widening our knowledge base on the complex phenotypic network of the Ae. aegypti response to insecticides.

Aedes↗
PubMed1976

Laboratory insecticide susceptibility tests against Mansonia larvae.

Insecticides Abate, DDT, Dowco-214, Dursban, fenitrothion, fenthion, gamma-HCH, and malathion were tested against the field collected fourth instars larvae of Mansonia from Penang Island, Malaysia. The larvae appeared to be highly susceptible to Dursban and Abate with LC50 values of 1.54 and 1.92 parts per billion respectively. Other chemicals, in decreasing degree of effectiveness, were gamma-HCH, fenthion, P,P'-DDT, Dowco-214, fenithrothion and malathion. The potential use of these chemicals in Mansonia control was discussed. A simple method for collecting and testing Mansonia larvae was also described.

Animals↗
PubMed1978

Abate--its value as a cyclopscide.

Guinea worm disease is highly endemic in Kurnool district in Andhra Pradesh. The effect of Abate on the vector cyclops was studied and was found to be very encouraging.

Animals↗
PubMedDate not supplied

[The control of Aedes (Stegomyia) and related species involved in transmission of human arbovirus infections in tropical Africa (author's transl)].

In Africa, many Aedes mosquitos are involved in yellow fever and dengue transmission. Their control can be carried out either in a "prophylactic" way, when no disease occurs, or in a "curative" one, when virus is detected in the human community. In the first event, control is confounded with sanitation measures; in the second event, insecticidal control is needed against both larvae and adults. Larvae populations are destroyed by means of insecticidal deposits in the breeding-sites. Control of adults is achieved by thermal fogs or U.L.V. applications of organophosphorous compounds dispensed from ground or aerial generators. The insecticide susceptibility level of every Aedes populations involved in arbovirus transmission must be periodically determined with all the insecticides available.

Aedes↗
PubMed1979

Effects of single and repeated exposures to abate on rat behavior and cholinesterase activity.

Rats were injected i.p. with the organophosphate insecticide ABATE and tested over the next 16 days. Animals given 1000 mg/kg showed impaired performance of a previously conditioned avoidance response 6 days after injection but not 2, 8, 10, or 16 days after injection. No behavioral changes were observed in animals given 316 or 562 mg/kg. A subsequent experiment showed that the avoidance impairment in animals given 1000 mg/kg was accompanied by significant erythrocyte, plasma, and brain cholinesterase activity inhibition and decreased spontaneous motor activity. If administration of the same ABATE dose was distributed over 6 days (167 mg/kg/day), cholinesterase and motor activity depression was still evident but conditioned avoidance performance was unimpaired. The results were interpreted as differential behavioral adaption to repeated injections of ABATE.

Animals↗