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At least 19 recordsLinked to original sources
PubMed1991

Trichophyton rubrum invasion of human hair apparatus in tinea capitis and tinea barbae: light- and electron microscopic study.

We have previously reported morphological changes of Trichophyton violaceum and Microsporum canis in hair apparatuses in tinea capitis. To investigate the morphology of Trichophyton rubrum in the human hair apparatus, two cases of tinea capitis and one case of tinea barbae were examined by light- and electron microscopy. The fungal elements, which were located in the lower keratogenous zone, showed non-septate hyphae in the outer part of the hair cortex. With the upward development of the hair layers, some hyphae invaded the keratinized hair cuticle and keratinized inner root sheath and were transformed into arthrospores. Some hyphae remaining in the hair cortex were also transformed into arthrospores, while other hyphae in the hair cortex did not survive, but degenerated. In T. rubrum hair infection, there is a distinct relationship between the morphological changes of the fungi and the hair cell differentiation as seen in T. violaceum and M. canis infections. However, T. rubrum displays unique morphological changes, which are different from those of T. violaceum and M. canis, in hair apparatuses.

Adult↗
PubMed1979

A study of Tinea capitis in Libya (Benghazi).

Tinea capitis formed 20% of all superficial mycotic infections, which in turn represented 12% of all skin disease diagnosed at the skin outpatient department of Al-Jamaheria hospital in Benghazi. The majority (94%) of tinea capitis occurred in children. A sample of 200 cases cultured revealed Trichophyton schoenleinii to be the most prevalent species of dermatophyte (69.5%) followed by Microsporum audouinii. (23.8%).

Adolescent↗
PubMed1990

Itraconazole in the treatment of tinea capitis.

Fifty patients with tinea capitis were treated with itraconazole, 25 to 100 mg/day, for 20 to 73 days in six countries. Forty-seven patients (94%) responded clinically (healed or markedly improved) to therapy, of which 38 patients (76%) completely healed and 9 patients (18%) markedly improved. Three patients (6%) failed therapy. Forty-two patients were assessable for mycologic examination; 38 patients (93%) converted mycologically to negative and 4 patients (7%) remained positive for organisms. In one group of 20 patients treated for 30 days, 6 patients were clinically and mycologically healed. By the 2-week follow-up visit 9 additional patients were healed, and 4 weeks after treatment all 20 patients were both clinically and mycologically healed. The primary organisms reported were Microsporum canis and Trichophyton tonsurans. Only one patient reported a possible side effect (tired legs). Laboratory values were all within normal limits, except for one patient who had a transient and slight increase in serum transaminase level. Low-dose itraconazole appears to be safe and effective in the treatment of tinea capitis.

Antifungal Agents↗
PubMed1991

Tinea capitis in three adults.

Three cases of tinea capitis in healthy adults are presented. In light of the very low incidence (less than 1%) of tinea capitis in nonimmunocompromised adults and the possibility of contagion from asymptomatic dermatophyte carriers in the pediatric and adult populations, the necessity for heightened clinical suspicion and diagnostic tenacity in the evaluation of adults with scalp dermatitis and/or alopecia for possible tinea capitis is underscored.

Female↗
PubMed1992

Brush-culture method for diagnosing tinea capitis.

Using traditional methods to verify the existence of a fungal infection in children with suspected tinea capitis is a cumbersome process. Scraping scale and pulling hairs for culture or microscopic examination can be time-consuming and uncomfortable for the child. This study is the first comparison of this method with an alternate brush-culture method for diagnosing tinea capitis. In 70 children with symptoms suggestive of tinea capitis, there was strong agreement between methods in detecting disease or lack thereof (McNemar's test, P less than .2). In the 51 paired positive cultures, those obtained by brush culture turned positive significantly faster (t test, P less than .01) than samples obtained by the traditional method. The brush method is a reliable, painless, and more expedient way to obtain cultures from children with suspected tinea capitis.

Adolescent↗
PubMed1991

Mycologic study of tinea capitis in Qatar.

The causative dermatophytic species of tinea capitis were identified in 91 patients in Qatar. Microsporum canis was the most common isolated organism (86.81%) followed by Microsporum ferrugineum and Trichophyton violaceum. A gray patch type of tinea capitis was the predominant presentation (87.91%), and the disease was more prevalent among Qatari boys.

Animals↗
PubMed1992

An open clinical pilot study of the efficacy and safety of oral terbinafine in dry non-inflammatory tinea capitis.

Ten patients with dry non-inflammatory tinea capitis were evaluated in a pilot study which ran from September 1989 to February 1990. Each patient was given oral terbinafine for 6 weeks; each was followed up 2 weeks later. Eight (80%) were completely cured, one (10%) was mycologically cured and showed minimal signs and symptoms, and another (10%) showed improvement (negative mycology, but persistent clinical signs and symptoms). No topical or systemic side-effects were noted. Terbinafine appears to be an effective and safe antifungal agent in the treatment of non-inflammatory tinea capitis.

Adolescent↗
PubMed1978

Intermittent use of griseofulvin in tinea capitis.

A total of 247 patients with tinea capitis were divided into two groups and treated with griseofulvin in two different ways: the first group received the drug every other day, and the second received it twice a week. The dosage was 5 mg/lb, with a maximum of 1 gm/day in both cases. In the first group, 99 percent of the patients were completely cured within seven weeks. Of those who received the griseofulvin twice a week, 91 percent were completely cleared within eight weeks. None of those in either group showed any signs of side effects from the medication.

Administration, Oral↗
PubMed1990

Tinea capitis in Tirupati.

One hundred clinically diagnosed cases of Tinea capitis were studied to know the clinical types and the causative agents. The incidence of grey patch, Kerion and black dot being 60%, 31% and 9% respectively. Tinea capitis was found to be more common in males (58%) than in females (42%) and it is more prevalent in children aged between 6-15 years. Trichophyton violaceum is the predominant (63.15%) fungal species isolated.

Adolescent↗
PubMed1992

Pathogenesis of hair infection and black dots in tinea capitis caused by Trichophyton violaceum: a histopathological study.

The majority of tinea capitis in southern Taiwan occur in adult women and are caused by Trichophyton violaceum. We report the histopathological findings of a series of 10 cases of tinea capitis caused by T. violaceum, the largest such study to date. Our study provides new information regarding the process of hair infection, mechanism of black dot formation, and chronicity of infection caused by this fungus. The cuticle remains intact. The fungi enter the proximal cortex where the cuticle is immature. They then colonize the proximal keratinized cortex and generate septate hyphae which transform gradually into arthrospores as they are carried upwards by the growing hair. At the infundibular level, the hair cortex is almost completely replaced by spores and swells, impeding further exit of the growing hair and causing the already weakened hair to coil up inside the infundibulum, forming a black dot. In one patient who had infection for more than 20 years, there were changes suggestive of cyclic reinfection of the same follicles which might contribute to the chronicity of the infection.

Adolescent↗
PubMed1979

Nonfluorescent tinea capitis in Charleston, SC. A diagnostic problem.

Statistics gathered at the Medical University of South Carolina from 1973 to 1978 indicate a dramatic change in the etiologic agents of tinea capitis in Charleston since the 1950s. The preponderant agent is now Trichophyton tonsurans, which produces lesions that are not fluorescent in a Wood's lamp examination (long-wave ultraviolet). Trichophyton tonsurans caused 90.6% of 265 culture-proved cases of tinea capitis in the 1970s, but in the 1950s it was responsible for only 1.6% of 378 cases. The study emphasizes that cultures are necessary because the increase in nonfluorescent tinea capitis throughout the United States presents unsuspected diagnostic problems to physicians who are not aware of the change in etiologic agents.

Black People↗
PubMed1979

A school survey of tinea capitis in Benghazi, Libya.

A school survey of Tinea capitis in Benghazi revealed an incidence of 4.49 per cent. The commonest clinical type which accounted for 87.7 per cent of the cases, resembled Seborrhoea capitis more than with any classical type described so far. T. schoenleinii and T. violaeceum were the most frequent isolates.

Adolescent↗
PubMed1975

Tinea capitis in Pondicherry (South India).

Amongst 125 cases of tinea capitis, representing 12-5% of dermatomycosis, about 9% showed kerion-like lesions and 13% had tinea corporis and/or tinea unguium. Eighty four percent cases were mycologically positive, yielding Trichophyton violaceum (84%) or T. tonsurans (16%).

Adolescent↗
PubMed1991

Tinea capitis in adults in southern Taiwan.

We report the clinicomycologic study of 27 culture-proven cases of tinea capitis from southern Taiwan during the years 1988 to 1990. The series is notable for its predominance of adults (63%), of women (89%), and of Trichophyton violaceum infection (74%). The age distribution was clearly bimodal; the median age was 6 years for children and 56 years for adults (older than 18 years). Whether or not these findings represent a new trend of tinea capitis in southern Taiwan remains to be determined. Clinically, our cases of black-dot ringworm caused by T. violaceum often presented with subtle changes of scaling, hair loss, and black dots. The keys to the correct diagnosis are (1) a high clinical index of suspicion with careful inspection of the scalp for the presence of black dots, and (2) microscopic examination and culturing of the black dots or plucked hairs.

Adolescent↗
PubMed1990

[Clinico-epidemiological findings in tinea capitis in adults].

Clinical and epidemiological data on 15 subjects with Tinea capitis are reported. The patients, aged between 19 and 74, were observed from 1.1.1980 to 30.6.1990; 14 of them were females. The evidence of different clinical pictures is stressed. Microsporum canis was isolated in 7 cases, Trichophyton violaceum in 6 cases, and Trichophyton schoenleinii in 2 cases.

Adult↗
PubMed1976

Follow-up study of patients treated by x-ray epilation for tinea capitis. Estimation of the dose to the thyroid and pituitary glands and other structures of the head and neck.

This study is a further investigation of radiation dose to various head structures in the children given X-ray therapy for tinea capitis (ringworm of the scalp). In this work, estimates of the dose to the thyroid and pituitary gland were obtained with lithium fluoride thermoluminescent dosemeters using a child's head phantom. Doses were also measured for the parotid gland and several skin sites where skin tumours developed in the irradiated cases. In a previous study, brain and scalp doses of 140 and 500-800 rad had been estimated for the treated group using this same head phantom. In this work dosemeters were also placed in the same brain locations so that comparisons could be obtained between the two studies. The thyroid dose was estimated to be 6 +/- 2 rad and the pituitary dose was 49 +/- 6 rad for the conventional tinea capitis treatment. The dose to the parotid gland was 39 rad and the dose to skin sites on the face and neck where tumours occurred ranged from 20 to 40 rad. The data for the thyroid adenoma response from this and other studies involving irradiation of children suggests a linear dose-response relationship within the first 30-40 years after exposure with a risk of about 0-04% per rad.

Adenoma↗
PubMed1979

[Tinea capitis: 73 cases observed in Bordeaux (author's transl)].

73 cases of tinea capitis were observed in the "Hôpital des Enfants" in Bordeaux during these last five year. 71 children under 14 years of age and only 2 adults have seen. The dermatophytic spectrum transformation noticed in other parts of Western Europe is also encountered in Bordeaux. 83 p. 100 are affected by zoo-antropophilic dermatophytes, M. canis chiefly in town, T. mentagrophytes, T. verrucosum in rural aeras. The cases are often familial, from an infected animal, but without any interhuman transmission. Only 8 out of 73 cases are due to strict antropophilic dermatophytes and are found in newly arrived immigrants from North Africa (T. violaceum, T. schönleini) of from West Africa (M. langeroni, T. ferrugineum, T. soudanense). Not a single case of scholar transmission could be observed. Cure by micronised griseofulvine per os (15 mg/kg/day) associated with local care was effective in all cases.

Adolescent↗