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At least 19 recordsLinked to original sources
PubMedDate not supplied

[Cellular composition of palatine tonsil imprints in the differential diagnosis of uncomplicated chronic tonsillitis with a tonsillo-cardiac syndrome and chronic tonsillitis with rheumatism].

The authors studied imprints of tonsillar sections stained both by the method of Pappeneheim and that of Stockinger and Kellner taken from 205 patients with chronic non-complicated tonsillitis, chronic tonsillitis with tonsillocardiac syndrome and chronic tonsillitis with rheumatism, the rheumatic process being of various stages of activity. A comparison of the preparations received shows that the organism's immunologic reformation resulting from the rheumatic process is characterised by growing reticulolymphoblastic, plasmocellular and macrophage reactions and vivification of sinuslymphocytopoiesis which proved to be in strict correlation with the extent of rheumatic activity.

Chronic Disease↗
PubMed1978

A scanning electron microscope study of the caecal tonsil: the identification of a bacterial attachment to the villi of the caecal tonsil and the possible presence of lymphatics in the caecal tonsil.

A scanning electron microscope (SEM) was used to compare the proximal region (PR) and distal region (DR) of the caecum. The caecal tonsil (CT) occupied the initial 4-10 mm of the PR. Villi were present in the PR and absent from the DR. Segmented structures were attached to the surface of PR. Transmission electron microscopy (TEM) revealed these structures to be bacteria. No difference in surface morphology could be discerned between the CT and the remainder of the PR. Lymphatic vessels were observed in the CT by employing TEM.

Animals↗
PubMed1977

[Role of the microbial flora of the palatine tonsils in the pathogenesis of chronic tonsillitis].

Species composition and the potency of a microbial focus of the microorganisms on the surface and in the lacunae of the palatine tonsils were studied in 51 patients suffering from chronic tonsillitis and in 52 healthy indivisuals. The species composition of the microorganisms was identical in the groups under study. However, its quantitative indices displayed significant differences. The potency of the microbial focus of the beta-hemolytic streptococci in the tonsillar lacunae of healthy individuals averaged 0.010 +/- 0.02 million, in patients with simple chronic tonsillitis-0.16 +/- 0.05, and in toxicoallergic tonsillitis of the I degree-1.03 +/- 0.8 million microbial cells. The constancy and a marked increase of all the species of microorganisms in the tonsillar lacunae of patients suffering from chronic tonsillitis, and also a marked dependence of this phenomenon on the extent of decompensation of the pathological process led to the conclusion that all of them played a definite role in the pathogenesis of this disease. It is supposed that the pathogenic influence of the mentioned microbes on human organism was realized both on account of summation of the antigenic-allergic and the infectious action, and by its other possible mechanisms.

Adult↗
PubMed1978

Immunoglobulin systems of human tonsils. II. Patients with chronic tonsillitis or tonsillar hyperplasia: quantification of Ig-producing cells, tonsillar morphometry and serum Ig concentrations.

Patients suffering from recurrent tonsillitis (RT), hyperplastic tonsillitis (HT) or idiopathic tonsillar hyperplasia (ITH) were compared in immunological studies with subjects showing clinically normal palatine tonsils. Serum concentrations of immunoglobulins, particularly IgG, were increased in association with tonsillitis. Conversely, the number of IgG-, IgA- and IgM-producing immunocytes was reduced per tonsillar tissue unit. The density of such cells was decreased in the germinal centres of the lymphoid follicles, in the extrafollicular areas and in the reticular parts of the crypt epithelium. However, only small changes in immunocyte class ratios were observed, excepting a significantly raised proportion of IgD-producing cells. The immunohistochemical results indicated a defect in the tonsillar immunological function associated with disease, perhaps as a result of inadequate stimulatory signals for local maturation of B-cell clones. An influence of low age on this result in the HT and ITH groups could not be excluded. In the RT group there was a significant negative correlation between the tonsillar density of IgA-producing cells and the rate of synthesis of serum IgA. This may indicate that compensatory mechanisms are reflected in inversely related levels of local and systemic IgA synthesis.

Adolescent↗
PubMedDate not supplied

Characterization of clinical tonsil stages by their T-cell count. Immunopathological description of tonsils after a peritonsillar abscess.

The T-cell counts in five different clinical tonsil stages are compared. No particularities were observed, with the exception of the condition after a peritonsillar abscess. The differences existing between the individual groups are discussed as age-dependent. A considerable increase in T-cells is found in the abscess tonsil compared with other tonsils and the T-cell count in blood. Its pathomechanism is discussed.

Adolescent↗
PubMed1976

[Palatine tonsils and immunity. VIII. Soluble factors produced by lymphocytes of the palatine tonsils and other lymphoid formations in rabbits].

A comparison was made of the activity of solbule factors produced by thelymphocytes of the palatine tonsils, the appendix, the spleen and thelymph nodes of rabbits in stimulation with a specific antigen (complete antigen of streptococcus, group A) and PHA. The blastogenic factor produced by the lymphoid cells of the spleen and the lymph nodes was highly active. Lymphocytes of the palatine tonsils and of the appendix produced a factor withlow activity after PHA stimulation. A factor intensifying the transformation in the presence of a complete streptococcus antigen was produced by lymphocytes of the spleen and the lymph nodes of the immunized animals. The lymphocytes of the palatine tonsils and the appendix failed to produce this factor.

Animals↗
PubMed1976

[Light microscopic findings of cryosurgically treated tonsils following chronic tonsillitis (author's transl)].

The light microscopic findings of tonsillar tissues from nineteen patients (aged 13-51) with the clinical diagnosis of chronic tonsillitis are described at sequential intervals following cryosurgical treatment. The Cooper instrument was used, containing liquid nitrogen and capacity limited cryoprobes as well as probes of a flow system. Two consecutive freeze-thaw cycles were used during a single session in each patient, with freezing time varied from 30 seconds to three minutes. In addition to primary cryosurgical tissue changes such as hyperemia, edema, inflammation, necrosis, fibroplasia with capillary increase, collagenous fibrosis and reepithelialisation, the following could be found: 1. A different cryosensibility of the cells and fibers within the cryolesion: The tonsillar septae are much more resistant to cold than the lymphoid tissue. Of this latter tissue, the reticulin cells and the lymphoblasts are more sensitive to the cold changes than are the matured lymphocytes. In the epithelium the stratum basale is as sensitive to cold as the lymphoreticulum. The outer epithelial cells are more resistant to cold than the basal cells. 2. A quick proliferation in the periphery of the cryolesion is seen in the form of an acanthosis and papillomatosis which begins before slough of necrotic debris occurs. 3. Sharp demarcation and protracted sloughing of necrotic epithelium from the free tonsillar surface or crypts and lymphoid tissue can be seen. 4. Reepithelialization can first be seen following slough of the cryonecrosis twenty days following cryosurgery, after which total reepithelialization occurs.

Adolescent↗
PubMed1978

Proliferation of cells and intracellular c-AMP content: comparative investigations of autologous lymphatic cells from palatine tonsils, nasopharyngeal tonsils, and blood.

The c-AMP content and thymidine incorporation were determined in tonsillogenic, adenoid, and peripheral lymphatic cells. A significant c-AMP decrease with simultaneous increase of the thymidine incorporation compared to the blood lymphocytes was noted in the tonsillogenic and adenoid cells. The negative regulative effect of c-AMP on cell proliferation and the function of tonsils at this processes are discussed.

Adenoids↗