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At least 19 recordsLinked to original sources
PubMed1978

[Clinical studies on the therapeutic effect of tinidazole ("Fasigyn") during treatment of urogenital trichomonas infections in women and men (with comparative laboratory studies on the effect of metronidazole and tinidazole)].

Tinidazole preparations are effective agents for the therapy of genitourinary trichomoniasis in women and men. The application of these drugs is very simple and, in particular, suitable as the application time is short and the occurrence of slight side effects shows a very low incidence. Unfortunately, these medicaments cannot be used during pregnancy and lactation. In addition, definite therapeutical recommendations are lacking and the published specific experiences in the therapy of obese persons with these drugs should be verified in future.

Adult↗
PubMedDate not supplied

Evaluation of the indirect hemagglutination technique for study of Trichomonas vaginalis infections, particularly in men.

The indirect hemagglutination (IHA) technique was evaluated for use in the serologic study of infection with Trichomonas vaginalis. The IHA test showed that sera from 88% of women attending a venereal disease clinic had antibody to T. vaginalis. The antibody frequency and titers were highest in women who had documented infections due to T. vaginalis. Serologic and cultural evidence of recent or active trichomonal infection was found in 11% of 85 men who had nongonococcal urethritis, but was absent in a control group of 27 men. Clinical findings in ten men with symptomatic genitourinary trichomoniasis are described; all but one had relatively high (greater than or equal to 1:80) IHA antibody titers. Antibody to T. vaginalis was found significantly (P less than 0.005) more often in sera from women than in sera from men in an apparently healthy group of individuals between the ages of 1 and 20 years. The IHA test appears potentially useful for the diagnosis of trichomoniasis in men and in the seroepidemiology of infections due to T. vaginalis.

Evaluation Studies as Topic↗
PubMed1978

Absence of detectable local antibody in genitourinary tract secretions of male contacts of women infected with Trichomonas vaginalis.

Samples of semen and urine were obtained from 37 male contacts of women with proved Trichomonas vaginalis infection; on culture, eight (22%) of the men were shown to harbour the parasite. However, significant amounts of antitrichomonal antibody were found in only two of these samples, and the amounts present were very small. A further 10 samples were tested but none was found to contain antibody. The asymptomatic nature and low parasite numbers commonly described in infections in men is thus unlikely to be due to a vigorous local immune response.

Animals↗