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[Present status and treatment of urogenital tuberculosis].

Urogenital tuberculosis has not decreased in incidence like other forms of tuberculosis and this is not to be expected in the coming years. Following combined modern chemotherapy the chances of conversion and also clinical cure are increased. The patient's cooperation during a systematic triple drug therapy in adequate dosage is important. The possibility of ambulatory treatment will depend on the clinical findings and the patient's social situation. Physical and occupational therapy and early resocialization of the patient are important. Prolonged unemployment should be avoided. Urological care of the patient is particularly important in the early phases of the treatment.

Drug Resistance, Microbial

[Modern therapy and after-care in urogenital tuberculosis].

The present therapy of the urogenital tuberculosis is based on the effective medicaments (rifampizin, isonicotinic acid hydrazid, streptomycin, and ethambutol). It rests on an optimum dosage in connection with a best suited combination, taking into consideration the relations of sensitiveness and side effects as well as consequent long-term treatment. It is referred to the possibility of additional administrations of corticosteroid preparations and it is taken notice to the necessity also to treat unspecific mixed infections. Under the modern chemotherapy with bactericidal effect a stable negativation practically always develops within 3 months. Actual recidivations were not seen during the last 12 years. Apart from a compilation of the indications to nephrectomy references to possibilities of plastic surgical corrections of the urinary system are given. Two tables give information about the patients who were operatively treated during the last 15 years. A close collaboration of the various therapeutic institutions with a consulting urologist -- particularly in problematic and advanced cases of the disease -- nearly always saves the patient with urogenital tuberculosis from invalidism.

Adrenal Cortex Hormones

[Results of conservative and operative treatment of urogenital tuberculosis (author's transl)].

In spite of the constant regression in newly notified Tbc patients, the percentage of extrapulmonary tuberculosis, especially of the urogenital region, remains unchanged at a high level. Modern therapy of urogenital tuberculosis is divisible into conservative, purely medicamentous treatment, possibly in combination with corticosteroids, and operative therapy, procedures preserving organs and rational eradication of tuberculous processes having to be carefully weighed against each other. The results of treatment are analyzed with reference to our own series of patients (n = 478).

Adolescent

[Clinical picture of urogenital tuberculosis].

On the basis of a survey on 28 cases with ascertained urogenital tuberculosis from 1971 to 1975 clinical picture and findings of the examinations are discussed. The cases in question are not a representative cross-section, since primarily ascertained cases of urogenital tuberculosis are treated in special departments. On account of the participation of the bladder which - compared with former cases - seems to be less frequent in interest of the early diagnosis is referred to the importance of the urinary findings and the excretion urography.

Adult

[The changed clinical picture of urogenital tuberculosis].

Of the 4500 urological patients treated in Weil Emil Hospital in Budapest, in 5 years 140 (3.1%) cases of urogenital tuberculosis were detected. In these cases earlier examinations failed to reveal the process which manifested itself one to six months. The number of those needing surgical intervention decreased considerably, 34 (24.2%) of the patients were operated. The clinical pattern has changed in our days and the possibility of an urogenital tuberculosis must be considered whenever no explanation can be found for the complaints and when even a single one of the characteristic symptoms of urogenital tuberculosis is observed.

Age Factors

Urogenital tuberculosis in Israel.

Forty-four patients were treated for urogenital tuberculosis in our ward from 1956 to 1975. Four patients were Israeli born and all the others were immigrants, mostly from Eastern Europe. Immigration greatly influences local morbidity, and tuberculosis is no exception. The highly developed preventive and social medicine of Israel has excellent results, and prognosis is more than favorable. Only one death was registered in our material, and this was due to renal failure of long duration.

Adult

[State and developmental trends of urogenital tuberculosis--20 years clinical and pathologic-anatomical experiences].

On the basis of own experiences of twenty years and taking into consideration the knowledge of other authors the developmental tendency in the treatment of the urogenital tuberculosis is demonstrated, the indications to nephrectomy, resection of the kidney, and epididymectomy are reified as well as kind and sequelae of errors in chemotherapy analysed. From 1958 to 1977 2,868 patients with urogenital tuberculosis were hospitalized in the Central Clinic Bad Berka. Of them about 41% had to undergo an operation. A decrease of the quantity of operations can be observed only in the renal resections, whereas the nephrectomy rate is unchangedly high (16.3% of the own patients) and even shows an increasing tendency since 1975. Comparative examinations show that the pathologo-anatomical picture of the ectomized kidneys has not changed during the period of observation. The knowledge of the symptom-poor course obliges also further on differential-diagnostically to take into consideration the urogenital tuberculosis. Only on this way the still large number of organ endangering complications may be encountered in time.

Epididymis