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Results for “ULTRAVIOLET THERAPY”

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At least 19 recordsLinked to original sources
PubMed1999

Basosquamous carcinoma after ultraviolet therapy with artificial sunlight.

We report a 63-year-old Japanese man with basosquamous carcinoma developing after ultraviolet therapy with artificial sunlight. Because he had had an eczematous lesion on the right leg five years previously, he had received ultraviolet therapy with artificial sunlight from a mercury-quartz lamp for a total of 30 sessions over a 3-year period. Physical examination revealed an irregular erythematous plaque measuring 5 x 6 cm, with slight eruptions and erosions, on the right leg. A brownish plaque, measuring 9 x 12 cm, surrounded the erythematous plaque. Histopathologically, in the nests of atypical cells in the dermis, nuclear palisading was present at the edge of each tumor cluster. Adjacent clusters exhibited transitions to squamous cells and contained horn pearls. Most of the cells of the epidermis and adnexa were atypical, but cells of the normal adnexal epithelium extended over the atypical cells of the epidermis in an umbrella-like fashion in other lesions. We believe that, in the present case, artificial sunlight therapy caused solar keratosis and that this developed into basosquamous carcinoma. To our knowledge, skin cancer developing after ultraviolet therapy with artificial sunlight without PUVA has not previously been reported in the English literature.

Carcinoma, Basosquamous↗
PubMed1997

Ultraviolet therapy of HIV-infected individuals: a panel discussion.

Patients infected with the human immunodeficiency virus (HIV) frequently develop skin diseases that are responsive to ultraviolet (UV) radiation. Studies on the effects of UV on HIV and on the immune system in vitro and in transgenic animals have raised questions regarding the safety of UV exposure in these patients. In this article, invited experts address issues concerning the safety of ultraviolet therapy in HIV-infected patients by discussing their clinical and/or research experience.

Animals↗
PubMed2001

Ultraviolet therapy in lupus.

This review examines the use of ultraviolet (UV) therapy in lupus erythematosus (LE), a disorder usually associated with abnormally increased photosensitivity. In addition to the abnormal cutaneous response to ultraviolet radiation (UVR) exposure, photo-aggravation of systemic disease activity in systemic LE (SLE) may also occur. However, courses of UVR exposure may also be used in the treatment or prophylaxis of various photodermatoses, and LE now appears to be included in that group. Thus, several studies have reported apparent benefits of phototherapy in both cutaneous and systemic LE, although the underlying mechanisms remain obscure and final confirmation of such efficacy is still awaited in continuing studies.

Humans↗
PubMed1990

Effect of ultraviolet therapy on rat skin wound healing.

Ultraviolet (UV) light therapy has been suggested as a treatment for pressure sores and crural ulcerations even though controlled trials are few. Therefore, the effect of UV light therapy on wound healing was studied in rat skin. A dose-dependent, significant improvement in the diminution of wound size was found between 4 and 15 days in wounds treated with UV as compared with untreated control wounds in the opposite side of the same animals. Wound closure, however, did not occur earlier in the treated wounds. UV had a marked warming effect; warmth alone without UV had no effect on wound healing. No significant difference was found in the tensile strength of UV-treated wounds at 7 and 15 days when compared with untreated wounds. Moreover, the intensity of the inflammation was equal in both treated and control wounds when studied histologically. We did not find any effect on clinical infection rate or bacterial colonization of the wounds. Although UV therapy seems to have an effect on wound healing in rat skin the present results are rather nonsupportive of the clinical benefits that are expected from this kind of treatment.

Animals↗
PubMed1982

[Experimental studies on the rheologic behavior of blood in ultraviolet therapy].

The increased apparent blood viscosity proved in peripheral circulatory disease, the frequent failure of therapy by means of vasodilating medicaments and the successful therapy with the help of ultraviolet radiation of blood (UVB) by means of various techniques motivated investigations of the flow properties of blood with UVB. In six patients with angiologically ascertained arterial occlusive disease the flow properties of blood were investigated under standardized conditions by both viscosimetric techniques and independent of it by means of the centrifugation method. Plasma viscosity, apparent blood viscosity, parameters of aggregation and deformation of erythrocytes were determined before and after fictitious UVB on the hand one and before and after real UVB on the other hand. It was shown that within the limit of measurement accuracy there were no significant differences between fictitious and real UVB in plasma viscosities. Both the aggregation parameter of the centrifugation method and the apparent blood viscosity for low shear gradients before the 3rd UVB and all following ones differed significantly from those of the first UVB. No changes were found in the deformation parameters HCC infinity and the apparent viscosity for high shear gradients during UVB therapy. Possible mechanisms leading to the demonstrated improvements of the flow properties of blood by means of UVB are discussed.

Arterial Occlusive Diseases↗
PubMed1989

Antigenic stimulation during ultraviolet therapy in man does not result in immunological tolerance.

People receiving therapy with either 8-methoxypsoralen plus long wavelength ultraviolet radiation (PUVA) or medium wavelength ultraviolet radiation (UVB) have been studied to see whether their unresponsiveness to the contact sensitizer dinitrochlorobenzene (DNCB) is a form of immunological tolerance. It was confirmed that both PUVA and UVB therapy impair sensitization by DNCB:4/13 PUVA-treated and 9/29 UVB-treated psoriatic subjects became sensitized by a dose of DNCB which sensitizes 100% of untreated patients. Subjects unsuccessfully sensitized during PUVA therapy could subsequently be sensitized perfectly normally. Subjects unsuccessfully sensitized during UVB therapy showed slight impairment of subsequent sensitization which was not statistically significant, and which was probably a persistent effect of UVB exposure. In conclusion, the temporary unresponsiveness seen in human subjects exposed to antigens during PUVA or UVB therapy is not due to immunological tolerance.

Antigens↗
PubMedDate not supplied

[Development of new ultraviolet therapy equipment for phototherapy].

The papers deals with the development of phototherapeutical ultraviolet radiation equipment, outlines the design and basic data of five new phototherapeutical radiation sources developed in the Laboratory of Medical Radiation Sources, VNIIMP-VITA joint stock company.

Equipment Design↗