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Results for “Urologic Neoplasms”

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At least 19 recordsLinked to original sources
PubMed1978

[The chemotherapy of urologic neoplasms].

The newest aspects for the use of cytostatic agents in the treatment of bladder, prostatic and testicular carcinomas are presented. Especially the two new drugs diaminodichlor cisplatinum and adriamycin are discussed as to their potential use in these diseases.

Cisplatin↗
PubMedDate not supplied

[Urologic neoplasms in patients with renal transplantation. Experience and review of the literature].

The presence of neoplasms in patients with renal transplant in a higher frequency than in general people is known since a long time. The most frequent tumours were the skin tumours, followed by other tumours common in immunosuppressed patients. The ain of this work has been study the frequency, type, diagnosis, treatment and evolution of the urinary system tumours in patients with renal transplant and an exhaustive review of literature. We have found 11 tumours of the urinary system over 57 tumours in 41 patients, with a frequency 26.8%. 6 were kidney tumours, 3 of prostate and 3 of the bladder. We have analyzed the incidence, diagnosis, treatment and evolution of tumour and its effects on the graft. We believe that the posttransplant follow-up of the patient, overcoat in males, who have tumours in more frequency, is important for the early diagnosis.

Adolescent↗
PubMed2002

Autopsy findings of patients with urological neoplasms.

BACKGROUND: A study was carried out to gain extensive understanding of the disease status in patients who had suffered and died of urological neoplasms. METHODS: The subjects were 524 patients who had died at the Department of Urology of Gunma Cancer Center. The autopsy rate for each urological, neoplasm, the extent of the disease, and incidental diseases were analyzed. RESULTS: Autopsies were performed in 27.1% (142/524) of the patients. Frequent metastatic sites were the lymph nodes, bone, and lung in prostate neoplasms; the lymph nodes, liver, and lung in bladder neoplasms; and the lymph nodes, lung, and bone in kidney neoplasms. In the 116 patients with these three major urological neoplasms, the autopsy findings of all patients were compatible with progression of the disease, except for 5 cases (acute myocardial infarction in 2 and liver failure in 3). Multiple primary cancers were seen in 21.6% (25/116), and other cancers that caused death, apart from those at urological sites, were confirmed in 7 patients (pancreas in 2, and esophagus, lung, gallbladder, liver, and uterus in 1 patient each). CONCLUSION: Autopsies revealed the macroscopic and microscopic extent of the disease and the presence of incidental disease beyond the diagnosis made in the patient's lifetime.

Adolescent↗
PubMed2000

Application of conditionally replicating herpes vector for gene therapy treatment of urologic neoplasms.

Herpes vector has been widely used for experimental gene therapy. We herein review the strategies of such therapy for the treatment of urologic neoplasms. Most experimental studies of genetically altered viruses have employed replication-incompetent vectors. However, such viruses are unable to infect additional cells subsequent to the initial infection event. Therefore, this strategy has relied heavily on the bystander effect because a large number of noninfected tumor cells remain. Conditionally replicating herpes vector G207 has been developed in order to overcome potential problems of safety and tumor specificity for human use. It has been used to treat malignant brain tumors because of its neural tropism. In the last few years, applications of G207 for non-neural tumors have been reported. Because G207 may be useful for the treatment of urologic malignant tumors, we evaluated the antitumor effect against several types of tumor cells both in vitro and in vivo. Our data suggest that G207 may be applicable for the treatment of urologic malignant tumors.

Animals↗
PubMed1990

[An evaluation of urinary Tamm-Horsfall protein coating cell in the diagnosis of urologic neoplasms].

By utilizing enzymic immunoassay, in a total of 161 cases of urologic tumors, Tamm-Horsfall Protein Coating Cells (THPC) could be found uniquely in the urines of renal tumors, whereas was absent in those of normal control as well as in the urines of transitional cell carcinomas of pelvis, ureter and bladder. Renal cell carcinoma predominated over in the THPC positive cases, among which granular cell carcinoma demonstrated a higher positive rate than that of clear cell type, 40% versus 15%. THP antigen could be found in the 66.6% frozen sections of renal cell carcinoma and the THP concentration in urine were also higher. Therefore, the detection of THP coating cells in urine of urologic neoplasm may be useful in evaluating the renal origin of the exfoliated tumor cells and elevating the screening accuracy of renal cell carcinoma, with no harms to the patients and no special equipment.

Adult↗
PubMedDate not supplied

[The role of C reactive protein in urological neoplasms].

The authors make a study of 46 urological patients (16 control and 30 neoplasia persons) determining the R.C.P. before and after the operations. The positive results obtained (77%) should lead to the said test becoming routine in uro-genital neoplasias.

Aged↗
PubMedDate not supplied

[Advance in the immunologic study of urologic neoplasms].

The reduction of the levels of circulating T lymphocytes in urological neoplasias seems obvious. The existence of a link between the different, neoplastic, bladder and prostate processes, as well as the degree of malignancy, prognosis and therapeutic response has still to be established, according to the immunitary state of the patients. The constant developing and refining of the immunological technology will no doubt serve to resolve these problems.

Adult↗
PubMedDate not supplied

[Trends in urologic neoplasm mortality and incidence (prostate, bladder, and kidney). Soria, 1950-1988].

The mortality rate for urological tumors in the province of Soria, Spain, was recorded from 1950 to 1988, as well as its incidence for the period 1981-1988. We classified data according to sex, age groups, tumor site and type, and patient residence (urban/rural). Rates were adjusted for the foregoing parameters and decades (1950-1959, 1960-1969, 1970-1979, 1980-1988) and compared with those of other national and international registries. Prostate, bladder and kidney tumors in men showed an increased mortality rate for the period 1950-1988 which was statistically significant (p less than 0.01), whereas the female mortality rate for this period hardly changed and remained very low. A higher risk potential was observed for bladder tumors for the urban than for the rural areas, with a significant difference for mortality and incidence for both sexes (p less than 0.01). There was also a higher incidence for tumors of the prostate in the urban areas (p less than 0.01). Like most registries, there was a prevalence of bladder tumors in males, in both areas, in mortality and incidence (p less than 0.01). Comparison with other national registries show our mortality and incidence rates are lower for both sexes. Comparison with international registries show this province has a medium-low risk for prostatic tumors and medium risk for bladder tumors in males and females. The risk potential for renal tumors could not be compared objectively. The incidence/mortality ratio (I/M) (adjusted rates) shows prognosis is good for bladder tumors (better in women than in men), poor for prostatic tumors, and bad for renal tumors.

Cohort Studies↗
PubMed1987

[Results of percutaneous cervical chordotomy in 35 patients with urologic neoplasms].

Between 1975 und 1985 we performed 281 percutaneous cervical cordotomies in 212 patients among whom there were 35 patients with urological malignancies. We report about the method, localisation of tumour and pain, results and complications. Altogether we can say, that percutaneous cervical cordotomy is an efficacious procedure with an acceptable complication rate in patients with chronic pain from malignant diseases especially in the urological field.

Adult↗
PubMed1978

[Course of cellular immunity in urologic neoplasms].

Apart from a purely qualitative evidence concerning the presence of a specific sensibilisation it is possible to estimate also its strength or the blocking factors appearing in the serum of tumour carriers by means of the electrophoresis mobility test. By this it seems to be possible to make an evidence concerning the immunological reaction position of the tumour patient with the possibility to make conclusions as to the prognosis of the patient.

Antigens, Neoplasm↗
PubMed1992

[Urologic neoplasms in AIDS].

Report on 2 cases of urological neoplasia in HIV positive patients. The first one is a renal adenocarcinoma in a heroin-abuser patient, of a type we have only found mentioned in the literature in 4 other cases. The second case was a disseminated Kaposi's sarcoma, the first symptom being a scrotum impairment and the biopsy suggested the diagnosis. This is believed to be an interesting communication considering the increasing number of anti-HIV antibodies carriers seen in our Units.

Acquired Immunodeficiency Syndrome↗