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At least 19 recordsLinked to original sources

[Double uterus and double vagina with unilateral imperforate vagina associated with ipsilateral renal agenesis: an infant case report].

Duplicated uterus associated with unilateral imperforate vagina and ipsilateral renal agenesis is a very rare anomaly. We report a case of a 10-month-old female infant presenting with pus discharge from vagina, and discussed the embryologic and clinical features relevant to this interesting disease complex with a review of the past literature. Echographic and CT examinations demonstrated a right-sided cystic pelvic mass. IVP revealed a left slight hydronephrosis and non-visualizing right kidney. No right ureteral orifice was found at cystoscopy. Under anesthesia the mass and pus was aspirated. Under the diagnosis of Gartner's cystic duct and a right renal agenesis or dysplasia with or without ectopic ureter, we subsequently performed laparotomy. Surgical exploration revealed a duplicated uterus with a normal ovary, and the mass was an imperforate right-sided vagina which communicated through the uterus. The diagnosis was changed to a double uterus with right-sided imperforate vagina, then the vaginal septum was excised. The post-operative course was uneventful, and pus discharge and the left hydronephrosis have disappeared.

Female↗

Characterization of a novel Atopobium isolate from the human vagina: description of Atopobium vaginae sp. nov.

Phenotypic and phylogenetic studies were performed on a hitherto undescribed micro-organism isolated from the human vagina. Comparative 16S rRNA gene sequencing studies demonstrated that the unknown strain constituted a new subline within the genus Atopobium. The unknown bacterium was readily distinguished from other Atopobium species by biochemical tests and electrophoretic analysis of whole-cell proteins. Based on phylogenetic and phenotypic evidence, it is proposed that the unknown bacterium be classified as Atopobium vaginae sp. nov. The type strain of Atopobium vaginae is CCUG 38953T.

Actinobacteria↗

Didelphic uterus, atretic unilateral vagina communicating with a double vagina, ipsilateral renal hypoplasia and ectopic ureter.

A case of didelphic uterus, unilateral atretic vagina with a small communication and a right-sided hypoplastic kidney is presented and illustrated by 'fistulography' and HSG. When a communication between the atretic and the normal vagina is present, the symptoms are often vague, clinically puzzling and can easily be misinterpreted. Because of the close relationship between the development of the urinary and the female genital tract, concomitant malformations are commonly found.

Abnormalities, Multiple↗

Congenital absence of the vagina. A clinical, histological and histochemical study on 17 patients with graft-constructed vaginas.

During a ten-year period 17 patients with total congenital absence of the vagina were treated by a split-skin inlay grafting technique. The average age at the time of operation was 21 years. Associated malformations, mostly afflicting the urinary tract, were found in 9 patients. The skin graft was applied on a perforated hollow acrylic mould, 12 cm long and 4 cm in diameter. The acrylic mould was removed on the tenth day and a soft silicon mould was then utilized for at least 6 months. The mean hospitalization time was 28 days. The grafts took completely in 11/17 patients and in the remaining cases the take averaged 80%. There was no major complication, such as fistulas, in the series. With the exception of two patients with male hermaphroditism all patients were contented with the operation and stated that they had a satisfactory sex-life. In 9/17 patients, a closer follow-up including a biopsy was made. The average depth of the vaginas was 8 cm (range, 6 to 10 cm), and the average diameter 3 cm (range 2.5 to 4 cm). The histological studies consistently showed that the original skin morphology was maintained in the recipient site.

Abnormalities, Multiple↗

[The clinical picture, diagnosis and therapy of duplication of the uterus and vagina with partial aplasia of one vagina in adolescents].

Fifteen girls aged 12 to 18 years have been evaluated and operated for unilateral hematocolpos related to uterus didelphys with a partially aplastic vagina. It most commonly occurred at puberty and characteristically presented as the onset of algomenorrhea at a few months following menarche, with deterioration of it during every menstruation, and suppurative discharge refractory to any therapy. The most revealing diagnostic approach was the gynecologic examination supported by pelvic and renal ultrasound scans. Surgical approach to this malformation consists in dissection of the walls of the rudimentary vagina.

Adolescent↗

Congenital absence of the vagina: in search of the perfect solution. When, and by what technique, should a vagina be created?

PURPOSE OF REVIEW: To review the Mayer-von Rokitansky-Küster-Hauser syndrome and to address means of diagnosis, patient education and counselling. The timing of, and vast options for, creation of a functional vaginal are also discussed. RECENT FINDINGS: The diagnosis of Mayer-von Rokitansky-Küster-Hauser usually occurs during an evaluation of primary amenorrhea. Counselling and support are of great importance for affected young women and their families. Educational materials have increased with the availability of Internet web sites and there is a vast number of options for creation of a functional vagina; most international centers promote the utilization of vaginal dilators. SUMMARY: Young girls, adolescents and women with Mayer-von Rokitansky-Küster-Hauser should be offered a comprehensive evaluation, and presented with information regarding all options for management and support. Ongoing psycho-social and educational support is extremely important. International centers that focus on congenital anomalies of the reproductive tract should be developed. These centers of excellence will facilitate long-term follow up studies to improve patient care and evidence based medical options.

Adolescent↗