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Results for “VITAMIN B COMPLEX”

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At least 19 recordsLinked to original sources
PubMed1996

Effect of vitamin B complex on neurotransmission and neurite outgrowth.

1. The effect of vitamin B complex (vitamin B1, B6 and B12) was studied on nerve conduction velocity in acrylamide-neuropathy rats maintained on refined semisynthetic complete vitamin and vitamin B-deficient diets in vivo and on neurite outgrowth in vitro using cells obtained from dorsal root ganglions of mice. 2. Acrylamide neuropathy was clearer in the group maintained on a refined semisynthetic vitamin B-deficient diet than in those on a refined semisynthetic complete vitamin diet. The neurotoxicity was lowest in the group given vitamin B complex prophylactic-therapeutically, next higher following therapeutic administration and last with no vitamin B complex administration in both groups maintained on a refined semisynthetic vitamin B-deficient diet and a refined semisynthetic complete vitamin diet. 3. The nerve conduction velocity tended to decrease by treatment with acrylamide. The decrement of nerve conduction velocity was partially inhibited by vitamin B complex. No significant difference was found in the groups treated with acrylamide and given vitamin B complex prophylactic-therapeutically and the control (no acrylamide treatment) in the group maintained on a refined semisynthetic vitamin B-deficient diet. 4. The greatest neurite outgrowth was found in the group treated with vitamins B1, B6 and B12-enriched medium, followed by the group of vitamin B12-enriched and vitamin B1-enriched media. All groups treated with a vitamin B-enriched medium had significantly greater (P < 0.01) outgrowth than the controls.

Acrylamide↗
PubMed1984

Newer laboratory methods for assessing nutriture of selected B-complex vitamins.

This review is limited to progress in the development of new or improved laboratory procedures to assess the nutriture of thiamin, riboflavin, niacin, vitamin B6, and folic acid. There has been marked progress in this area for the other vitamins as well. The increased availability of radioassay techniques and HPLC methodologies that have application in nutrition assessment is significant. However, for a number of the vitamins, there is still a need for additional methods that provide functionally interpretable preclinical information and give accurate assessment of body reserves of the nutrient. Often the guides used to interpret the information obtained are tentative and require validation or revision. This situation is further complicated by the frequent lack of suitable reference standards for quality controls and interlaboratory validation.

Alanine Transaminase↗