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Results for “Vitamin B Complex”

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At least 19 recordsLinked to original sources
PubMed1976

Interactions between malnutrition and primaquine studied on Wistar rats. II. Complex vitamin B deficiency and thiamine deficiency.

The action of primaquine was investigated on male Wistar rats depleted on the vitamin B complex (approximately 50% of their requirement for optimal growth), on thiamine (approximately 50% of their requirement for optimal growth), and pair-fed control animals. There was only a marginal increase in adverse primaquine reactions in the malnourished, especially in the thiamine deficient rats.

Animals↗
PubMedDate not supplied

[Effect of carbon and nitrogen sources and complex B vitamins on the synthesis of alkaline protease by different strains of Bacillus mesentericus and Bacillus subtilis].

The effect of different sources of carbon, nitrogen, amino acids and vitamins on the synthesis of alkaline proteases by the stock and mutant strains of Bacillus mesentericus and by the natural strain of Bacillus subtilis-12 has been investigated. The maximum synthesis of alkaline protease has been obtained in the media containing starch or its hydrolysates--dextrine and maltose as the carbon source. Ammonium phosphate and casein as the nitrogen source prove to be optimal for Bac. mesentericus and Bac. subtilis, respectively. Complex B vitamins added to the nutrient medium accelerate the enzyme synthesis 2.5-4-fold.

Ammonia↗
PubMed1978

Effects of an anabolic steroid and vitamin B complex upon myopathy induced by corticosteroids.

In rats repeatedly treated with dexamethasone, body weight decreased severely, creatine content in urine increased, tetanic contraction of the gastrocnemius muscle decayed easily and twitch tension of the muscle had a slow rise time. In a group of rats given large doses of vitamin B complex along with the anabolic steroid, nandrolone phenylproprionate, all syndromes described above for the dexamethasone-treated rats were prevented, dose dependently by vitamin B complex. The individual components of the vitamin B preparation combined with the nandrolone phenylpropionate partially suppressed the changes induced by dexamethasone. Diphenylhydantoin depressed the slow rise time of twitch tension as effectively as did vitamin B complex with nandrolone phenylpropionate. From the results presented here and facts previously reported it was concluded that the condition of the animals could be well controlled by repeated administration of vitamin B complex with nandrolone phenylpropionate, even though dexamethasone was repeatedly injected.

Animals↗
PubMed1976

B-complex vitamins in cultured and acidified yogurt.

Studies were to determine the effect of various factors upon B-vitamin content of cultured yogurt and to compare the B-vitamin contents of cultured and direct acidified yogurt. Incubation of yogurt culture at 42 C for 3 h yielded maximum vitamin synthesis concurrent with optimal flavor and texture qualities. A method was standardized for the manufacture of direct acidified yogurt involving the use of Stabilac acidulant and nonfat dry milk, Carboxymethyl cellulose, gelatin, and Starite. Acidified yogurt showed a slightly higher content of certain B-vitamins than the cultured yogurt due to the contribution made by various food additives. Both cultured and acidified yogurt showed good keeping quality and freedom from microbial contaminants during storage at 5 C for 16 days. However, folic acid and vitamin B12 contents decreased 29 and 60% in cultured yogurt and 48 and 54% in acidified yogurt.

Dairy Products↗
PubMed1976

Malnutrition and susceptibility to infection with Vibrio cholerae in vervet monkeys (Cercopithecus aethiops). 1. Induction of protein, B-vitamin complex and calorie malnutrition.

Five groups of eight vervet monkeys (Cercopithecus aethiops) were fed regular monkey chow, low protein (LP), low B-vitamin complex (LBV), low protein - low B-vitamin complex (LB-LBV), or protein - low calorie (LP-LC) diet, respectively, for eight weeks. Hematocrit values, hemoglobin, BUN, total protein, albumin, riboflavin and body weight decreased, the ratio of dispensable/indispensable amino acids increased in all animals receiving a deficient diet. Total globulin, IgG and IgM remained unchanged in vervets on LBV diet; panthotenic acid and cyanocobalamin in animals receiving LBV, LP or LP-LC chow; and pyridoxal on the LP or LP-LC diet.

Animals↗
PubMed1992

[Simultaneous analysis of vitamin B complex by least square UV-spectrophotometry].

Simultaneous analysis of VitB1, VitB2 and VitB3 in Vitamin B Complex tablets was made by least square UV-spectrophotometry. The results showed that the contents of VitB1, VitB2 and VitB3 could be calculated by computer with least square method using 12 absorbances of 239, 241, 257, 259, 261, 263, 266, 269, 270, 279 and 281 nm wavelengths. The reclamation of VitB1 was 101.4% (CV% = 0.88, n = 3), of VitB2 98.5% (CV = 0.43, n = 3), and of VitB3 101.3% (CV% = 0.15, n = 3).

Least-Squares Analysis↗
PubMed1979

[Effects of vitamin B complex in functional changes of the peripheral nerves of alloxan-induced diabetic rats (author's transl)].

Neurophysiological properties of the peripheral nerves of alloxan-induced diabetic rats and effects of vitamin B complex (V) were studied. Alloxan monohydrate was administered to Wistar (38 mg/kg, i.v.) and Sprague-Dawley (SD, 45 mg/kg, i.v.) rats. In Wistar diabetic rats (blood sugar level: more than 400 mg/dl for 6--8 weeks), nerve potentials with 2 peaks were recorded from the tibial and peroneal nerves. The late component had a higher threshold, longer time of recovery from excitation and slower conduction velocities. Large doses of V (B1: 100, B6: 100 and B12: 1 mg/kg, i.p.) administered daily until the experiment inhibited the appearance of the late component. In SD diabetic rats(the same blood sugar content for 6 approximately 8 months), the ventral root potentials had a longer duration, higher threshold and longer time of recovery from excitation. In V administered rats, particularly along with insulin, these changes were prevented. Most efferent fibers of non-treated rats had a refractory period of less than 3.0 msec. The number of fibers with this refractory period was greatly reduced in the diabetic rats. Although rats administered each component of V 100 and V 50 had efferent fibers with similar refractory periods to that of rats in A-S group, those administered V 100 had efferent fibers with significantly shorter refractory periods. Thus, efferent fibers seem to be more sensitive than the afferent ones at the early stages of the long term diabetic state and a large dose of V, particularly along with insulin, depressed these changes.

Action Potentials↗
PubMed1976

Malnutrition and susceptibility to infection with Vibrio cholerae in vervet monkeys (Cercopithecus aethiops). 2. Response of vervet monkeys on protein, B-vitamin complex and calorie-deficient diets to infection.

Five groups of vervet monkeys (Cercopithecus aethiops) were fed regular monkey chow, low protein (LP), low B-vitamin complex (LBV), LP-LBV, or low protein- low calorie (LP-LC) diets, respectively. After eight weeks the animals were infected with cholera vibrios. IgG, IgA and IgM increased in the sera of all animals after the challenge but the avidity of the immunoglobulins was lower in vervets on LP diets. Diarrhea and excretion of vibrios lasted longer in animals consuming less protein.

Animals↗
PubMed1978

[Changes in cholinesterase activity of gastrocnemius and soleus muscles of the rat after crush of the sciatic nerve, and effects of a vitamin B complex on those changes (author's transl)].

In an analysis of the gastrocnemius muscle, the microsomal fraction showed the highest cholinesterase (ChE) activity. The ChE activity of all fractions decreased to a greater extent after strong nerve crushing than after weak crushing. This change in the activity in the microsomal fraction was the most marked change observed. Although in the analysis of the soleus muscle the ChE activity was measured only in the homogenate and in the microsomal fraction, the results were the same as those obtained with the gastrocnemius. A preparation of vitamins B1, B2, and B12 (B complex) had little effect on the ChE activity in the gastrocnemius muscle. In the soleus muscle on the lesion side, the B complex increased the ChE activity to some extent after nerve crushing, but such was not significant. However, the B complex signifiicantly increased this activity in the soleus on the intact side. In the soleus muscle, strong nerve crushing induced more marked muscle atrophy than weak crushing. On the other hand, no significant difference was found in the gastrocnemius. Effects of the B complex on muscle atrophy were found in the soleus, but not in the gastrocnemius. These results suggest that the ChE activity in the microsomal fraction containing sarcoplasmic reticulum reflects the nervous disorders clearly, and that the B complex increases the ChE activity and muscle weight in the soleus, but not in the gastrocnemius muscle.

Animals↗
PubMed1978

[Effects of a vitamin B complex on functional recovery after nerve injury (author's transl)].

Functional recovery after nerve crushing was investigated in the following manner: Under pentobarbital anesthesia the sciatic nerve of the rat was crushed at the level of the hip (proximal crush) or the thigh (distal crush). The recovery processes after the nerve crushing were followed by measuring distances between the first and fifth digits(DBD.1 approximately 5) and between the second and fourth digits (DBD.2 approximately 4) of the hind paw, and by observing changes in "behavior" scored on a scale of 10 according to the degree of behavioral disorder of the hind paw and leg. Results obtained by these methods showed good reproducibility. The DBD values and the scores for behavior recovered significantly faster after weak nerve crushing than after strong crushing, and after distal rather than after proximal crushing. When a segment of the sciatic nerve was resected, there was no recovery. These results suggest that DBD.1 approximately 5, DBD.2 approximately 4, and the behavior observed in these experiments serve as good indices for evaluating the degree of functional recovery after nerve injury in unanesthetized and unrestrained animals. Effects of a preparation of vitamins B1, B6, and B12 (B complex) on these three parameters and on weights of 9 muscles of the hind leg were also studied. These studies showed that the B complex facilitated functional recovery from nerve injury faster than its components, and that on muscle atrophy the B complex had its most effects on the soleus. It was also shown that B1 and B12 by themselves had significant facilitating effects on the functional recovery.

Animals↗