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At least 19 recordsLinked to original sources
PubMed1975

[Monocytic leukemias with unusual clinical presentations].

In clinical hematology the terms "monocytic" leukemia and "reticulosis" still -require better definition and classification. By presenting the histories of eight patients and by cytology and cytochemistry it is shown that myelo-monocytic leukemias can have the course well-known for an acute leukemia, including different skin lesions, as well as that of an typical chronic granulocytic leukemia. In dermatology monocytic leukemias were considered as belonging to the entity of the so-called reticulosarcomatosis cutis. However, strict differentiation from the hiary cell leukemia is to be made today. The general term "reticuloses" has quite faulty been used formerly for classification of these last two disorders.

Adult↗
PubMed1979

Clinical presentation and management of lacrimal gland tumours.

This paper presents the clinical and pathological findings in 40 consecutive patients seen with primary tumours arising from the lacrimal gland. Twenty patients had a benign mixed-cell tumour. They presented in a recognisable clinical manner with a painless mass in the region of the lacrimal gland which slowly enlarged over a period of at least 1 year before consultation. Twenty patients had a carcinoma of the lacrimal gland. They had a short history and experienced pain. On clinical grounds they could not be distinguished from inflammatory lesions in the region of the lacrimal gland. The method of treating these 2 groups of patients is described and methods of dealing logically with their problems are suggested.

Adult↗
PubMedDate not supplied

Chondromalacia patellae in athletes. Clinical presentation and conservative management.

A comprehensive conservative management program for chondromalacia patella in athletes has been presented. The clinical manifestations and the efficacy of conservative treatment have been documented in the prospective study of 100 consecutive athletes. The over-all success rate was 82%, and 18% were considered to be failures of conservative treatment. Only 8 of these 100 athletes have required surgical treatment. It was concluded that this type of conservative management is effective in the majority of athletes with symptomatic patellofemoral syndromes, and that surgical treatment should be necessary for only the relative few who fail to respond to an adequate trial of conservative treatment.

Cartilage Diseases↗
PubMed1975

The clinical presentation of mesenteric vascular disease.

The clinical presentation of 17 patients with mesenteric vascular disease admitted to Mount Sinai Medical Center was reviewed. The signs and symptoms were similar in most cases. However, the acute onset of the symptom triad of abdominal pain, diarrhea, and bloody stools in an elderly patient should make one suspect the possibility of mesenteric vascular disease. The gross and light microscopic appearance of the intestinal tract was characterized by hemorrhagic infarcts regardless of the cause of the bowel ischemia. Mortality from this disease remains high, with only four of our 17 patients alive four months after operation.

Acute Disease↗
PubMed1975

[Proceedings: Clinical presentations in nephrology].

Four clinical cases are presented: (a) cured systemic lupus erythematosus, fracture of the odontoid process of the axis; (b) renovascular stenosis following renal transplant; dissecting aneurysm of aorta, consolidated for the last 3 years; (c) rejection glomerulonephritis following renal transplant; (d) unusual complications in a patient of intermittent hemodialysis for the last 8 years.

Accidents, Traffic↗
PubMed1978

Clinical presentation of patients with "dyspepsia". Detailed symptomatic study of 360 patients.

This paper describes the clinical presentation of 360 patients suffering from "dyspepsia" at the time of their initial visit to two hospitals in Yorkshire. Disease categories studied were cholecystitis, duodenal ulcer, gastric ulcer, gastric cancer, and "functional" dyspepsia, with at least 50 patients in each category. The findings of this series are contrasted with "textbook" descriptions of these conditions. Some contrasts are quite surprising-for example, most of the 360 patients claimed that their pain was not aggravated by food. It is suggested that one reason for diagnostic error in this area of medicine is that clinicians have a faulty mental "database" of information with regard to the presentation of the various diseases concerned.

Adult↗
PubMed1976

Clinical presentations and mechanisms of necrotizing angitis of the skin.

Cutaneous necrotizing angiitis may be present as either palpable purpura or less commonly as recurrent urticaria, and each clinical presentation may be associated with hypocomplementemia or a normal complement system. A variety of mechanisms may be operative in the production of necrotic vascular skin lesions that appear as similar, recognizable morphologic lesions. These mechanisms include immune complexes, cellular-type hypersensitivity reactions, and initiation or modulation by mast cells. Two cellular patterns have been recognized in the skin of patients with cutaneous necrotizing angiitis that can be correlated with the involvement of the complement system in serum. In patients with hypocomplementemia, there is an infiltrate of neutrophils that is consistent with a process involving immune complexes; in patients with normocomplementemia there are lymphocytes and activated lymphocytes consistent with participation in part by cellular mechanisms. In both the hypocomplementemic and normocomplementemic forms and as well as in a unique patient in whom the mast cell may initiate the venular damage, the mast cell, which its content of chemical mediators, has the capacity to initiate as well as modulate subacute and chronic vascular damage.

Antigen-Antibody Complex↗
PubMed1977

The clinical presentation of Gilbert's disease in 26 patients.

Twenty-six patients with Gilbert's disease (congenital, non-haemolytic unconjugated hyperbilirubinaemia) were analysed regarding their clinical presentation, age at onset of symptoms, sex, frequency of symptoms, family history, race and religion. Seventy-three per cent were men, the mean age at onset of symptoms was 21 years, and frequency of symptoms ranged from 4 times a year to once every 5 years. The symptoms, which were extremely vague, included the following: recurrent asymptomatic jaundice in 74%, malaise in 66%, asthenia in 65%, and vague abdominal distension in 52% of patients. Eight per cent of patients were totally asymptomatic. There did not appear to be any particular race or religious group with a higher incidence of the disorder. No abnormal clinical features apart from mild jaundice were detected. The entirely benign nature of the syndrome is stressed, and a normal life expectancy is the rule. The avoidance of prolonged fasting is the best therapeutic measure, although enzyme induction by phenobarbitone therapy may have some place in the management of symptoms.

Adolescent↗
PubMed1978

[The clinical presentation and management of otogenic intracranial disease (author's transl)].

Since the introduction of antibiotics in the treatment of ear infection the number of otogenic intracranial complications has decreased. Furthermore the clinical presentation of these complications has likewise since changed. The traditional symptoms and signs as mentioned in the literature are replaced by an indefinite inflammatory course, which is finally succeeded by rapid progress of the disease despite the use of antibiotics. Experiences with 22 patients are reported. Temporal lobe brain abscesses occurred in 11 patients, meningitis occurred in 3 others and lateral sinus thrombophlebitis occurred in 8, in 2 of whom meningitis also occurred. Five patients died as a result of the intracranial complication. After establishing the diagnosis the recommended treatment is the immediate surgical clearance of the primary aural abscess, together with if possible drainage of the intracranial abscess or evacuation of the lateral sinus disease under appropriate antibiotic cover. Whether the patient with intracranial disease is subsequently handled in the ORL or Neurosurgical wards depends upon ward facilities and interdepartmental liaison and cooperation.

Brain Abscess↗
PubMed1978

Mucinous carcinoma of anal duct origin presenting clinically as a vaginal cyst.

The vast majority of vaginal submucosal cysts are benign lesions. Primary malignant tumors of the vagina are infrequent and most are mucosal lesions. A case is described in which an unusual neoplasm, anal duct carcinoma, presented clinically as a vaginal lesion. The importance of considering anal neoplasia in the differential diagnosis of cystic vaginal lesions is noted.

Adenocarcinoma, Mucinous↗
PubMed1975

Clinical presentation of infection in granulocytopenic patients.

Inability to accurately diagnose infection in granulocytopenic patients is a major cause for morbidity and mortality, and prompted this study of 344 infections (pharyngitis, skin infection, pneumonia, anorectal infection, and urinary tract infection) in a select group of cancer patients. Strikingly similar alterations in clinical presentation were found for all infections that developed in profoundly granulocytopenic patients. Physical findings of exudate, fluctuation, ulceration or fissure, local heat, swelling, and regional adenopathy were all less prevalent in the granulocytopenic patient, while fever was much more common. Only erythema and local pain or tenderness were present in practically all patients regardless of site of infection or level of granulocyte count. A better understanding of how granulocytopenia affects the presentation of infection should lead to earlier and more accurate diagnosis and potentially to more successful therapy.

Adolescent↗
PubMed1976

An unusual clinical presentation of pancreatic carcinoma: Duodenal obstruction in the absence of jaundice.

A case of pancreatic carcinoma, presenting with the uncommon initial manifestation of vomiting secondary to duodenal obstruction without jaundice, is reported. A review of 72 consecutive biopsy-proven cases of pancreatic carcinoma admitted to our institution in the past five years revealed an 8.3% incidence of this unusual primary complaint. Although infrequently reported previously, pancreatic carcinoma should be considered in the differential diagnosis of gastric outlet obstruction in the absence of jaundice. The classic triad of progressive jaundice, weight loss and abdominal pain suggests carcinoma of the head of the pancreas. Emesis, secondary to high grade duodenal obstruction in the absence of jaundice, is an infrequent clinical presentation. The case described is illustrative of widespread pancreatic carcinoma that remained silent until obstruction developed.

Adenocarcinoma↗
PubMed1978

Fibrous epulis: experience in clinical presentation and treatment of 39 cases.

The clinical features and treatment of 39 cases of fibrous epulis are described. Many of the epulides attained giant sizes before patients sought treatment. A few large or recurrent fibrous epulides were mistaken for malignant lesions, such as fibrosarcoma, Burkitt's lymphoma, or squamous cell carcinoma. Adequate excision and histological examination of all tissues excised were found to be the best management procedure for fibrous epulis.

Adult↗
PubMed1979

Changes in clinical presentation of term infants with intracranial hemorrhage.

The clinical course and outcome of eight term infants with intracranial hemorrhage are reported. Before computerized tomography became available, term infants with intracranial hemorrhage were usually diagnosed only at autopsy and the hemorrhage was associated with a trauamtic birth or severe asphyxia. In contrast, since the availability of computerized tomography, term infants with a diagnosis of intracranial hemorrhave have a non-traumatic delivery, present with seizures, and survive.

Cerebral Hemorrhage↗
PubMed1975

Chromosomes of cattle: present clinical status and promise.

Current information on cytogenetics in veterinary medicine is presented as a resume for the veterinarian in cattle practice; previous reviews of the subject are recorded. The literature depicting the recognised chromosome abnormalities in cattle is breifly reviewed. It is suggested that chromosome screening already has a role to play in the economics of cattle production.

Animals↗
PubMed1977

The changing clinical presentation of coeliac disease in adults.

A diagnosis of coeliac disease was confirmed in 57 patients referred to a gastroenterology clinic over a 5 1/2-year period. Although diarrhoea was present in two-thirds of the patients, this was the major symptom leading to referral in less than half of them. When present, diarrhoea was usually intermittent and frequently not typical of steatorrhoea. Symptoms were of less than six months' duration in half the patients, but a review of the past and family history strongly indicated the possibility of coeliac disease in 39 of the 57 patients. A high spontaneous abortion rate during pregnancy was noted. The frequent absence of the classical features of malabsorption, diarrhoea with typical steatorrhoea and chronic debility was noted. All screening tests for malabsorption were found to be unreliable and their routine use was rarely justified. A random serum folate and carotene assay proved as valuable as more expensive and troublesome tests. It is stressed that in any case in which there is a clinical suspicion of this diagnosis, a small intestinal biopsy should be undertaken.

Abortion, Spontaneous↗