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At least 19 recordsLinked to original sources

[Considerations on a pathology of the diaphragm. 1st Report: the pathology of the diaphragm as a part of a pathology of respiration (author's transl)].

The first part of this paper deals with the idea of a "pathology of the diaphragm" and its special relations to the respiration on phylogenetical and ontogenetical base. A pathology of diaphragm does not exist until now. The diaphragm represents an important respiration organ in orthological and pathological conditions. The function of this organ is described and derivated from its specific anatomical structure and topographical site. In this conception the pathology of the diaphragm is a part of the complex pathology of the respiration. A systematic presentation of diaphragm diseases will follow in a second part of this paper.

Animals

[The development of child pathology within the framework of pathology and pediatrics. A medico-historical review].

1. The history of child pathology is derived from the description of the development of the an pathological anatomy and paediatry. 2. The pathological anatomy of infancy is basing on the research results of the general and special pathology, the pathological physiology and the clinical medicine by the help of the experiment and the knowledges of biology, chemistry, and physics. 3. Further decisive impulses are given by social medicine.

Allergy and Immunology

Suggested procedures for reducing the pathology workload in a carcinogen bioassay program, Part II: Incorporating blind pathology techniques and analysis for animals with tumors.

Large testing programs have been set up to help assess the carcinogenic potential of chemicals introduced into the environment. Most test protocols used in these programs require extensive pathologic evaluations of all test and control animals. In Part I we proposed modifications to such complete pathology protocols which would allow substantial reduction in pathology workload while making only small changes in the operational character of the screen. The modifications suggested did require that slides from controls and treatment animals be handled differently and they did not call for a total tumor analysis (i.e. they do not allow blind pathology). In this paper we discuss how blind pathology can be incorporated and suggest a procedure to recover the "total tumor" aspect. It is emphasized that these modifications should be regarded as a starting point for further discussion and that we encourage comments from all interested scientists.

Animals

The future of pathology: a Delphi study by pathology department chairmen.

This paper reports the results of a study by and of chairmen of pathology departments in American and Canadian medical schools directed toward discovering chairmen's perceptions and attitudes about the future of pathology. Over 100 of a total of 143 chairmen participated in some or all phases of this study in which the Delphi approach was used. Sixty-five chairmen completed all four rounds of questionnaires. Most chairmen are deeply concerned about increasing federal regulation of medicine. They expect to play a greater role in all phases of medical education with more emphasis on the basic science aspects of pathology. They also foresee a desirable shifting of residency training programs away from small hospitals to the larger medical centers. This shift will result in fewer but longer training programs.

Attitude

Forensic pathology--the hidden specialty: A survey of forensic pathology training available to medical students and residents.

It is no wonder that some people refer to forensic pathology as the "hidden specialty." This paper shows evidence that the only exposure given to most medical students is a brief, all-too-explicit demonstration ("horror show") of interesting cases that can only attract the bizarre of mind into the field. It is further pointed out that even residents in pathology receive scanty, if any, formal training in most medical school residency programs, in spite of the fact that two thirds of the medical schools responding have one or more forensic pathologists on their faculty. The obvious answer is a change in the curriculum if this increasingly important subspecialty is to be saved.

Curriculum

Changing concepts in the management of pathological and impending pathological fractures.

The benefits in the management of pathological fractures by internal fixation are well recognized. However, failures in bone or metal can occur where there is a large amount of bone destruction. Seven of 69 pathological fractures in our series were treated by internal fixation with adjunctive use of methylmethacrylate without failure. This allowed for secure fixation in fractures with large amounts of bone destruction, thus decreasing the patient's pain and allowing earlier mobilization. Neither the effects of radiotherapy on bone involved with neoplasm nor methylmethacrylate are altered when radiotherapy is used after internal fixation and adjunctive use of methylmethacrylate. We believe that an aggressive program of stabilization of these fractures or fixation before actual fracture provides significant patient benefits including reduction of pain, decreased length of hospital stay, reduction of financial expense, and return to as near normal function as possible.

Adolescent

[Osteoplastic epitympanotomy and the pathology of the middle ear. Part 2: The microstructures of the epitympanum and their significance concerning the pathology of the retrotympanal spaces (author's transl)].

The two goals of osteoplastic trepanation of the middle ear spaces are first a direct inspection of the main areas of pathologies within the epitympanum and secondly a better understanding of the infected middle ear diseases through careful preparation and exposure of the pathologic processes. A new way of approval could be found by taking into account the anatomical and topographical realities and the possible deviations form normal cases. This opens a better understanding of all those variations. Without touching the microstructures of the tympanum their inspection and preparations are hereby made possible macro- and microscopically. This leads to the conclusion that the tympanic structures are involved in the formation and progression of infected middle ear diseases. The correlation of the "aeration pathways" and the "drainage outlets" of the middle ear as an interdepending functional unit can be seen by this new intrasurgical inspection-based on light- and electronic microscopic research of various authors-as well as through the fact that middle ear mucous membrane is a truly respiratory membrane with no difference to other aeration pathways as found in the nose. A of a summation of mucous membranes in the area of the diaphragma is that minor catarrhal inflammations will block this aeration pathway of the middle ear. At the same time an open tuba auditiva can be found in acute, subacute and chronic middle ear diseases. Our findings that the ventilation of the ear is in most cases blocked at the diaphragma and not at the tube leads to questions on the one hand regarding the function of diaphragma and to the opinion on the other that the ventilation system of the middle ear is divided in two sections by the diaphragma: An anterior section including tuba and hypomesotympanon and a posterior including epitympanon, aditus, antrum and the pneumatic cells of mastoid and pyramid. The anterior section still is ventilated through the tuba when blocked at the diaphragma, in the posterior one ventilation and drainage are blocked even by mildly infected processes. Longer lasting infections have severe consequences for these spaces and the tympanic membrane.

Acute Disease

[Pathology in Malagasy lemurs and their relation to human pathology].

From researches conducted in Institute Pasteur in Madagascar and from bibliographical work, the authors try to draw up a general picture of the pathology of lemurs. Several aspects are developed (bacteriology, hematology, mycology, parasitology, virology), especially those which could be interesting for human pathology, for instance the relationships between lemurs and viruses because of the arbovirus programme in progress in Institute Pasteur. The authors emphasize on the possible use of lemurs, the only non human primate in Madagascar, as laboratory animals in order to develop colonies and, then, to promote their conservation.

Animal Diseases

Joint Committee on Aviation Pathology: VII. Aviation pathology in relation to aviation safety.

The mainstay of accident-prevention programs--and accident prevention programs, after all is said and done, are the ultimate objective--has been to educate populations exposed to certain hazards with respect to the nature of the risks involved. While human engineering can frequently limit or diminish the hazard potential in a given situation, it is unlikely that mechanical contrivances alone will offer a pragmatic solution to the human-factor accident. I would invite this group to expend its talent in further developing the application of clinical pathology as well as pathologic anatomy to the still-unanswered problems in aviation safety and join with us at the Naval Safety Center in an effort to make our air operation as safe as possible.

Accidents, Aviation

Eosinophilic gastritis. Radiologic-pathologic correlation (RPC) from the Armed Forces Institute of Pathology (AFIP).

Eosinophilic gastroenteritis may involve the gastrointestinal tract locally ofr diffusely. When localized to the stomach, the preferred terminology is "eosinophilic gastritis". Pathologically, this entity is characterized by a high eosinophil count (which closely follows the symptomatology) and diffuse infiltration of the antral wall by eosinophils. Typical roentgenographic manifestations include gastric antral rigidity, thickened folds, and mucosal nodules. The differential diagnosis is discussed. Correct diagnosis is vital because of the benign nature of the disease and good response to conservative therapy.

Adult