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Results for “social determinants”

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At least 19 recordsLinked to original sources
PubMed2026

Association between cumulative social disadvantage, as measured by the social determinants of health score, and epilepsy: a cross-sectional study.

BACKGROUND: Social determinants of health (SDoH) shape access to care, health behaviors, and long-term outcomes, yet their cumulative relationship with epilepsy has not been well quantified. This study examined whether a composite SDoH score was associated with epilepsy in adults. METHODS: This cross-sectional study used data from the National Health and Nutrition Examination Survey 2013-2018. The SDoH score ranged from 0 to 8 and summarized eight unfavorable social conditions. Epilepsy was identified using medication-based ascertainment. Survey-weighted logistic regression models were applied to evaluate the association between SDoH score and epilepsy. Restricted cubic spline, subgroup, sensitivity, and receiver operating characteristic analyses were also performed. RESULTS: A total of 13,119 participants were included, of whom 114 had epilepsy. Participants with epilepsy had a higher mean SDoH score than those without epilepsy (3.41&#xa0;&#xb1;&#xa0;0.24 vs. 2.35&#xa0;&#xb1;&#xa0;0.06, P&#xa0;<&#xa0;0.001). In the fully adjusted model, each 1-point increase in SDoH score was associated with 31% higher odds of epilepsy (OR 1.31, 95% CI 1.16-1.48). Compared with the low-score group (0-2), the adjusted odds ratios were 2.09 (95% CI 1.06-4.15) for scores of 3-5 and 2.67 (95% CI 1.34-5.33) for scores of 6-8. Spline analysis showed a significant overall association without evidence of nonlinearity. Adding SDoH components to demographic variables improved model discrimination (AUC 0.731 vs. 0.589, P for difference <0.001). CONCLUSION: Greater cumulative social disadvantage, as reflected by the SDoH score, was associated with higher odds of epilepsy.

Humans↗
PubMed1975

Social determinants of alcohol and marijuana effects: a systematic theory.

Based on the sociological perspective on recreational drug effects, three social determinants are propositionally related to the normal effects of alcohol and marijuana. Effects vary across drugs, users, and situations along an experimental-behavioral dimension termed "effect-orientation." The content of normative expectations toward effects and the interactional characteristics of drug-using situations are conceptualized as direct determinants of effect-orientations. The relative clarity of normative expectations indirectly influences effect-orientations through its relationship to the other two social determinants. The theory stresses the importance of comparative research on the normal uses of alcohol and marijuana.

Behavior↗
PubMed1979

Social determinants in food selection.

Responses of 112 low-income homemakers to questions about the food use frequency, availability, and social determinants (convenience, price, and prestige) of fifty-two food items are reported. Results indicate that foods have clear meaning profiles that can be measured on attitudinal scales. Bivariate analysis was used to illustrate the interrelationships between food-use frequency and social determinants. Significant correlations were found between food use and convenience, price, prestige, and availability for fourteen of the fifty-two food items studied.

Adult↗
PubMed1979

Social determinants of violence in hockey: a review.

Research on the social determinants of hockey violence is organized in this paper under three main headings: (1) the social organization of the hockey "system", (2) mass media portrayals of the professional game, and (3) the influence of players' reference others. It appears that these determinants all contribute to a social environment in which hockey performers perceive that the rewards of violence often outweigh the costs.

Adolescent↗
PubMed2026

Social Determinants of Health and Clinical Outcomes in Hypertrophic Cardiomyopathy.

IMPORTANCE: Area-based indicators of social determinants of health (SDOH) are associated with higher risk for acquired heart disease, but their impact on conditions with a strong genetic etiology, such as hypertrophic cardiomyopathy (HCM), is not well understood. OBJECTIVE: To determine the association of area-based SDOH with clinical outcomes in patients with HCM. DESIGN, SETTING, AND PARTICIPANTS: This multicenter, prospective cohort study was conducted among US adult patients with HCM from 5 sites in the Sarcomeric Human Cardiomyopathy Registry (a multicenter prospective registry of patients with HCM) who were followed up for a median (IQR) period of 2.15 (0.15-5.82) years. Data were entered from 2015 to March 2024, and data analysis was completed from March 2024 to June 2025. EXPOSURES: Patients' residential addresses were geocoded at the zip code level and linked to the American Communities Survey to estimate area-based (1) median household income and (2) social deprivation index (SDI), which ranges from 0 to 100, with higher scores indicating a more deprived area. MAIN OUTCOMES AND MEASURES: Multivariate models, adjusting for age at diagnosis, body mass index, hypertension, and sex, were used to estimate the independent association of area-based median household income and SDI with heart failure (HF), ventricular arrhythmias (VA), and an overall composite outcome (VA, HF, atrial fibrillation, stroke, and death). RESULTS: Among 4431 US adult patients with HCM, median (IQR) age at HCM diagnosis was 51.3 (38.9-61.6) years, and 1862 patients (42.0%) were female. Median (IQR) area-based household income was $80&#x202f;000 ($60&#x202f;000-$110&#x202f;000), and median (IQR) SDI was 25 (10-55). Adjusted hazard ratios comparing the lowest income group to the highest income group were 2.07 (95% CI, 1.77-2.42; P&#x2009;<&#x2009;.001) for HF, 1.31 (95% CI, 0.97-1.78; P&#x2009;=&#x2009;.08) for VA, and 1.52 (95% CI, 1.36-1.69; P&#x2009;<&#x2009;.001) for the overall composite outcome. Adjusted hazard ratios comparing the highest SDI (ie, more deprived) group to the lowest SDI group were 1.48 (95% CI, 1.29-1.70; P&#x2009;<&#x2009;.001) for HF, 1.55 (95% CI, 1.15-2.09; P&#x2009;=&#x2009;.004) for VA, and 1.36 (95% CI, 1.22-1.50; P&#x2009;<&#x2009;.001) for the overall composite outcome. CONCLUSIONS AND RELEVANCE: In this multicenter cohort study, residing in an area with lower median household income or worse SDI were each independently associated with adverse clinical outcomes in patients with HCM. These findings suggest that despite the genetically determined nature of HCM, place of residence is associated with patient outcomes.

Humans↗
PubMed1992

Biological and social determinants of the Lyme disease problem.

Lyme disease, presently the most common arthropod-borne disease in the United States, is a phenomenon of both medical and social importance. Notwithstanding the substantial public health threat posed by Borrelia burgdorferi infection, there is reason to suspect that the diagnosis of Lyme disease is made more frequently than justified. On the other hand, the current dissatisfaction with serologic assays for B. burgdorferi infection may lead some physicians to inappropriately abandon consideration of the diagnosis entirely. Either of these outcomes of the patient-physician encounter is to be regretted. The Lyme disease problem, as I call the current situation, has both biological and social determinants.

Humans↗
PubMed1992

Socialization to dying: social determinants of death acknowledgement and treatment among terminally ill geriatric patients.

Although the vast majority of deaths occur among terminally ill geriatric patients, little is known about the etiology of these patients' death acknowledgement and ultimate type of treatment. Based on interviews with 76 triads composed of physicians, terminally ill patients, and primary caregivers, this study uses the socialization perspective to identify the actors and actions that most strongly affect the patient's death acknowledgment and receipt of exclusively palliative care (i.e., socialization to the dying role). Whereas patient preferences and sociodemographic characteristics do not influence significantly the patient's odds of death acknowledgment, these odds are increased if their primary caregivers accept death, their physicians are not affiliated with a teaching hospital, and the terminal prognosis is disclosed to them and disclosed "matter-of-factly." Patients who acknowledge death, whose agents value pain alleviation over life-prolongation, and whose physicians are not affiliated with a teaching hospital, are substantially more likely to receive exclusively palliative rather than curative terminal treatment.

Adaptation, Psychological↗
PubMed1992

Environmental and social determinants of sexual function in the male lesser mouse lemur (Microcebus murinus).

Environmental factors that regulate the sexual activity of male lesser mouse lemurs have been studied experimentally with more than 60 captive animals over an 8-year period. In this nocturnal Malagasy prosimian, variation in day length is the primary factor controlling seasonal sexual activity. Plasma testosterone concentrations were low (= 9 ng/ml) during short days and reached 60 ng/ml during long days (> 12-hour day). This cyclic pattern persists unchanged when artificial photoperiodic rhythms are applied and is not altered by ageing. The timing of puberty is also regulated by photoperiodic changes. Nevertheless, the sexual activity of the male lesser mouse lemur can be dramatically modified by the social environment. In heterosexual groups, behavioural and physiological components of sexual activity are depressed in all males except the dominant one, whose aggressive interactions are always successful. Intermale sexual inhibition was shown to be mediated by chemical cues present in the urine of dominant or isolated males but not in urine of subordinate individuals. The inhibitory signals possess lipophilic properties and are not contingent on the gonadal activity of the urine donor but are linked to adrenocortical activity. By contrast, chemical signals stimulating the reproductive function of all males are found in the urine of females, the presence of which is required for the establishment of clear dominance among grouped males. Endocrine mechanisms underlying intermale sexual inhibition by chemical cues were analysed. Variations in prolactin strongly suggest that olfaction interacts with the photoperiodic regulation of reproductive function, leading to changes in the sensitivity of the negative feedback effect of testosterone on gonadotrophin secretion. Inhibitory or stimulatory effects of chemical signals are discussed in the context of their functional significance for wild populations.

Aggression↗
PubMed1992

The role of sports as a social status determinant for children.

This study was designed to examine children's attitudes toward the role of sports in determining social status, as well as the activities in which children prefer to participate. A total of 227 boys and 251 girls in Grades 4, 5, and 6 completed a questionnaire to determine which criteria were most important in determining personal, female, and male popularity. Personal popularity was answered by the girls and boys according to "what would make you well liked by your classmates." Female and male popularity was determined by asking both girls and boys to decide "what would make (girls, for female subjects, and boys, for male subjects) well liked by your classmates." A comparison of results from the Buchanan, Blankenbaker, and Cotten (1976) investigation and the present study indicated that, in the last 15 years, appearance has become more important and academic achievement less important in determining personal popularity for girls. For boys, the comparison revealed that sports have become more important and academic achievement less important in determining personal popularity. Boys reported sports to be the most important determinant of personal and male popularity and appearance as the most important determinant of female popularity. Sports and appearance became more important for boys with each higher grade level. Girls reported appearance to be the most important determinant of personal, male, and female popularity. For girls, appearance became more important with each higher grade level. A comparison of results from the Buchanan et al. (1976) and the present study indicated that the activities in which girls and boys preferred to participate have changed.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗