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Tortuosity as an index of the age and diameter increase of coronary collateral vessels in patients after acute myocardial infarction.

A possible correlation among increase in diameter, lengthening or tortuosity and age of bypassed obstruction was investigated in coronary arterial collateral vessels. In 35 autopsy patients with a myocardial infarct of known age, as determined from clinical history and pathologic demonstration of an infarct of consistent age in the distribution of an obstructed vessel, 140 collateral vessels were identified in postmortem arteriograms and measurements made of their diameter and tortuosity. Multivariable regression analyses showed that collateral diameter and tortuosity increase with greater time after the infarction. It is suggested that identification of tortuosity in a coronary vessel may provide an indication that it functions as a collateral channel and of the degree of its dilatation and the time it has been a collateral channel. The lengthening that produces tortuosity probably arises from the same relaxation of medial tension that induces dilatation as a result of increased blood flow.

Adult

Retinal arteriolar tortuosity with retinal haemorrhage. A case report.

Retinal arteriolar tortuosity with retinal haemorrhages was first described in 1958. In the present article, a case of recurring retinal haemorrhages combined with retinal arteriolar tortuosity is reported. The medical examination and laboratory tests did not reveal pathology except for a slightly increased bleeding time. There were no similar cases in the family. The cause of the haemorrhages is still unknown.

Adolescent

[Recurring retinal haemorrhages with tortuosity of the retinal arteriols (author's transl)].

Four young and healthy adults with tortuosity of the retinal arterioles of the posterior pole and recurring superficial retinal haemorrhages are described. Two of them had a suspected mild thrombocytopathy without clinical manifestations in other organs. Inheritance of the syndrome was not demonstrated and the pathogenic mechanism still remains obscure. All the described patients had been at risk of a retinopathy of praematurity. Knowing that familial retinal haemorrhages without retinal tortuosity do occur and retinal tortusity may persist as a minimal change of retinopathy of praematurity, it is suggested that this syndrome might be a combination of two entities.

Adult

Measurement of vessel tortuosity on fundus photographs.

Quantitative measurement of vessel tortuosity and its variation on fundus photographs is a sensitive means of obtaining information about the course of an asphyctic event in newborns, virtually independent of bias produced by the photographic process. We subdivide a tortuous vessel into single arcs and measure the chord length and the arrow height (Pfeilhöhe) of every arc on a projected image of the film. From these figures, a fairly accurate value for the relative length increase of the arc, as compared with the chord, can be derived by a simple approximation formula [Eq. (5)]. It is shown that neglect of the third dimension, not visible on an ordinary photograph, entails only a small error. Trained observers achieve results reproducible to about 1% in relative length variation.

Asphyxia Neonatorum

Right-sided cervical aortic arch associated with tetralogy of Fallot and peculiar tortuosity of the descending aorta.

A right-sided cervical aortic arch, tetralogy of Fallot, and a peculiar tortuosity of the descending aorta in which the aorta formed triple loops were diagnosed by angiocardiography in a 12-year-old girl. Histologic examination of the biopsied wall of the left subclavian artery, taken at the time of a Blalock-Taussig anastomosis, revealed no elastic-tissue defect.

Angiocardiography

Tortuosity of the cavernous carotid arteries causing sellar expansion simulating pituitary adenoma.

Tortuous, medially-displaced cavernous carotid arteries may cause sellar enlargement which simulates pituitary adenoma. Systemic hypertension appears to account for this tortuosity in some cases, while a congenital anomaly is probably responsible in others. Medical position of the carotid sulci may be demonstrated on sellar tomography. Cerebral arteriography provides the correct diagnosis. Surgery, particularly transsphenoidal hypophysectomy, should be avoided in such patients.

Adenoma

Vessel tortuosity as a cause of posterior fossa cranial nerve syndromes.

Neurologic syndromes may be caused by mechanical vascular compression of cranial nerves in the posterior fossa. The clinical expression is variable and can be divided into two main groups. Isolated cranial nerve involvement is most frequently associated with tortuous, elongated vertebral and basilar arteries as well as redundant loops of the anteroinferior cerebellar artery. Pseudotumoral manifestations of cranial nerve involvement at the level of the cerebellopontine angle are more frequently related to aneurysms of the vertebral and basilar arteries.

Adult