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Biomedical subjects

A A Iudin

Publications and source records attributed to A A Iudin.

At least 19 recordsLinked to original sources
PubMed1996

[Diagnosis and surgical treatment of distal congenital intestinal aganglionosis in children].

The article contains the analysis of the additional diagnostic methods in children with Hirschsprung's disease. The main role belongs to the histobiochemical investigation of the rectal mucosa that can help to estimate acetylcholinesterase activity for the diagnosis of distal aganglionosis. The results of 100 biopsies in 93 children with chronic obstipation were examined. The analysis helped to find correlation between chronic constipation and activity of acetyicholinesterase. The use of hystobiochemical method helped to determine the distal form of congenital aganglionosis in 20 children. 10 patients had surgery with good results in short-term postoperative period.

Acetylcholinesterase↗
PubMed1991

[Correction of postoperative fecal incontinence in children].

The results of surgical treatment of II-III degree incontinence of feces in 6 patients previously operated on for anorectal anomaly are presented. Clinico-functional examination permitted topical verification of damage to rectal sphincter apparatus. Sphincterolevatoroplasty with the use of a posterior sagittal approach was performed. The given approach permitted maximum use of the preserved muscular elements of the obturator apparatus. In a number of cases sphincterolevatoroplasty was combined with smooth muscle plasty of the internal anal sphincter from the distal colon. The functional results followed in 5 patients were considered as good and satisfactory ones.

Anal Canal↗
PubMed1980

[Thromboresistant properties of polyelectrolyte complexes based on weak polyelectrolytes].

Thrombogenic resistant polyelectrolyte compositions were obtained on the basis of weak polyelectrolytes used in different quantity proportions. The investigations were performed in vitro on rabbit blood and in vivo on 21 dogs and 5 calves in the conditions of acute and chronic experiments. The optimal compositions of polymers were selected for the implantation. The appropriate polyelectrolyte compositions on the basis of weak polyelectrolytes, and polymers modified by polyacryl acid with polyethylene piperazine (1:1, 2:1, 3:1), were found to be thrombogenic resistant and did not cause any significant blood cells damage. The investigations performed the possibility for their practical application.

Animals↗
PubMed1975

[Change in catecholamine and acetylcholine concentration in myocardial tissue in assisted circulation].

The authors stress the importance of reactions associated with the concentration of biologically active substances in the body tissues, in particular their influence on the contractility and escitability of the heart muscle. They cite the results consequent upon a study on the catecholamines and acetylcholine content in the myocardial tissue of the left ventricle and left auricle of the heart before and after institution of an auxilliary circulation effected with the aid of a valveless pump connected to the subclavicular artery in 22 dogs. An analysis of the results demonstrated that by producing counter-pulsation with the pump the concentration of catecholamines and acetylcholine in the tissues of the left head diminishes, but the fall of the catecholamines concentration does not reach the level typical of cardiac insufficiency. The authors believe that investigations of this kind may help elaborate optimal conditions and a permissible duration of the auxilliary circulation.

Acetylcholine↗