[Diarrhea syndrome in the practice of internal medicine physicians].
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Biomedical subjects
Publications and source records attributed to A A Sheptulin.
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Antisecretory effect of intravenous quamatel (Q) and gastrocepin (G) was studied in 59 patients with duodenal ulcer. Mean maximal pH and delta-pH in antral portion of the stomach and its body were similar for Q and G, but pH responded to Q administration faster. The antisecretory effect of Q was more pronounced in males and young patients and was inversely proportional to initial acidity.
Characteristics of personality and emotional condition were studied in 160 patients from Moscow (Russia) and Chardzhou (Turkmenistan) with various gastroenterological diseases: duodenal ulcer, chronic gastritis, chronic cholecystitis, irritable colon syndrome. Actual psychogenia occurred frequently in all the patients, children's psychogenia was more frequent in Moscow patients with duodenal ulcer. In patients with duodenal ulcer and chronic gastritis both from Moscow and Chardzhou the incidence of stress in everyday life was rather high. All the examinees suffered from mild or moderate depression found more frequently in Moscow patients with chronic gastritis.
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Most authors advocate surgery for peptic ulcer because of the high frequency of malignancy of the ulcers. The literature data and personal observations provide evidence, however, that true malignant degeneration of the ulcer is a quite rare complication of the disease. Of greater importance in examination of the patients is differential diagnosis between benign ulcers and the infiltrative-ulcerous form of gastric ulcer which may take the "mask" of a benign ulcer in the early stages. Patients with an uncomplicated form of peptic gastric ulcer must be given nonoperative treatment. An operation should be considered only in formation of poorly cicatrizing ulcers with due regard for the poor efficacy of their nonoperative management.
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