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Biomedical subjects

A Arnoux

Publications and source records attributed to A Arnoux.

30 records · Page 2Linked to original sources
PubMed1975

[Mercury pollution of the superficial sediments of the Gulf of Lion].

Mercury pollution in the superficial sediments of the continental shelf of the golfe du Lion, is characterized by an important extension in its eastern part, which is under the direct influence of the Rhône river, and more limited and fragmented in itw western part. Between both these zones, territories with low contamination persist, of which the hydrodynamism prevents the advance of dense particles containing mercury.

France↗
PubMed1975

[Study of the distribution of haptoglobin groups in Marseilles, in normal and in cancer subjects].

Authors have studied 758 sera from normal subjects in Marseille area. The genotype frequencie Hp 1 is 0,39, similar that of France in general. The phenotype repartition is 16% for Hp 1-1, 45% for Hp 2-1 and 39% for Hp 2-2. People with carcinoma have shown a increase of the frequencie of the phenotype Hp 2-2 and a decrease of the frequencie of genotype Hp 1, mostly in lung carcinoma (Hp 1 = 0,29) and in carcinoma of digestive track (Hp 1 = 0,19). However, a control group, which is constituted by people hospitalized in the Anti-Cancerous Center, has a Hp 1 frequencie of 0,29 a well as lung carcinoma, no explication was found.

France↗
PubMedDate not supplied

Primary cutaneous nocardiosis in an immune-competent patient.

We present a patient who was hospitalized due to a purulent skin lesion with a surrounding erythematous area in the region of the right paranasal crease accompanied by a swelling of the right eyelid. Initially the diagnosis of a carbuncle caused by an infection with Staphylococcus aureus was supposed. A surgical debridement was performed and an antibiotic therapy was started. Only special microbial investigations requested by the clinician led to the diagnosis of a cutaneous infection with Nocardia brasiliensis. The presented case is remarkable because the nocardia infection was in an immune-competent patient and the patient showed a primary cutaneous nocardiosis without dissemination.

Amoxicillin↗
PubMedDate not supplied

[Effects of a controlled Staphylococcus aureus infection on the renewal of endoalveolar cells].

We have studied, in rats, the influence of the intratracheal injection of 30 X 10(6) Staphylococcus aureus upon the differential count and renewal of the cell populations extracted by pulmonary lavage. In vivo labelling of alveolar macrophages was performed by intratracheal injection of 125I iododeoxyuridine, and the evolution of the labelled population was quantitatively followed up after scheduled sacrifice. Dividing cells were also identified at all times in the lavage population, after incorporation of (3H)-thymidine in vitro and autoradiography. The injection of Staphylococcus aureus induced an acute inflammatory process followed by the migration of polymorphonuclears, lymphocytes and macrophages mainly during the first 24 hours. Later on, no viable bacteria were observed and the cell populations returned to control values. Kinetic parameters were found varying as a function of the cell type. The early increase of macrophages was mainly produced by the migration of monocytes, which exhibited a shorter lifespan in alveolus than did resident macrophages. The inflammatory reaction observed, whilst inducing a considerable modification of the cell distributions, did not significantly modify the lifespan of macrophages located within alveolus before the aggression.

Animals↗
PubMedDate not supplied

Pulmonary edema and shock after high-dose aracytine-C for lymphoma; possible role of TNF-alpha and PAF.

Four out of 23 consecutive patients treated with high-dose Ara-C for lymphomas in our institution developed a strikingly similar syndrome during the perfusion. It was characterized by the onset of fever, diarrhea, shock, pulmonary edema, acute renal failure, metabolic acidosis, weight gain and leukocytosis. Thorough bacteriological screening failed to provide evidence of infection. Sequential biological assays of IL-1, IL-2, TNF and PAF were performed during Ara-C infusion to ten patients, including the four who developed the syndrome. TNF and PAF activity was found in the serum of respectively two and four of the cases, but not in the six controls. As TNF and PAF are thought to be involved in the development of septic shock and adult respiratory distress syndrome, we hypothesize that high-dose Ara-C may be associated with cytokine release.

Acute Kidney Injury↗