PubMed Health⌕ Search

Biomedical subjects

A B Safran

Publications and source records attributed to A B Safran.

139 records · Page 8Linked to original sources

[Internuclear ophthalmoplegia in infectious encephalitis: observation on a case of listeriosis].

An internuclear ophthalmoplegia was diagnosed and recorded electro-oculographically in a patient with pontomedullary listeriosis. The etiological differential diagnosis in case of internuclear ophthalmoplegia is discussed. It is emphasized that listeria monocytogenes encephalitis should be considered because this pathology may be electively located in the pontomedullary area and because of the encreasing frequency of human listeriosis.

Adult↗

[Modifications of the pupil in acute subdural hematoma].

This study is based on the observation of 81 operated acute subdural haematoma. The various coordinates concerning the clinical aspects and the evolution are analysed in function of the presence or absence of pre-operatory anisoria. The discussion abords the gravity of this sign and its value in localizing the lesion, as well as the clinical distinction between ipsi-lateral and contra-lateral mydriasis. Possible subdivisions in cases of contra-lateral relative mydriasis, as well as their probable pathophysiological mechanisms and respective clinical and prognostic implications are also examined.

Acute Disease↗

Corneal hypoesthesia.

Decreased corneal sensitivity is an important clinical parameter in neuro-ophthalmological evaluation. It may be associated with such disorders as diabetes, Herpes simplex keratitis, and myasthenia gravis, with corneal toxicity via chemical exposure or ocular drug therapy, and with ocular surgery. In this review, methods and precautions involved in measuring corneal sensitivity are summarized, and the clinical conditions in which corneal hypoesthesia may exist are discussed.

Cornea↗

The vanishing of the sun: a manifestation of cortical plasticity.

In Monet's painting impression. Rising Sun, when one steadily fixates the image of a sailor in the center of the picture for several seconds, the solar disk progressively disappears, being replaced in both brightness and color by the surrounding sky. This "filling-in" phenomenon reflects a process of cortical remapping, similar to the one that occurs in the presence of visual field defects. Filling-in is largely ignored by clinicians, despite its major implications in ophthalmologic practice, especially the nonrecognition of visual field deficits.

Color Perception↗

Ocular tilt reaction associated with a sudden idiopathic unilateral peripheral cochleovestibular loss.

We recently observed a female patient who was suffering from acute right peripheral cochleovestibular loss associated with a marked vertical diplopia. Otoneurological examination showed profound deafness, and absence of nystagmic response to caloric and pendular rotatory test in the right ear. Neuroophthalmological examination showed skew deviation with right hypotropia, excyclotorsion, and tilt of the static visual vertical directed to the right side. Immunological and serological examinations were normal. Neurological examination and extensive neuroradiological investigations failed to demonstrate any central nervous system involvement. In this patient, skew deviation and tilt of the static visual vertical were interpreted as signs of an acute unilateral otolithic dysfunction, due to a sudden idiopathic peripheral vestibular loss.

Diplopia↗

[Evaluation of retinal function following central serous retinopathy and diffuse epithelial retinopathy].

The so called "benign" central serous retinopathy is associated in healed forms with frequent and troublesome visual function impairment. The abnormalities are still more severe after diffuse retinal pigment epitheliopathy. Snellen visual testing is relatively imprecise index of visual function, so it does not permit to appreciate the subtle visual disturbances experienced by these patients. We evaluated visual function disability with static automatized perimetry and contrast sensitivity in 30 patients with diffuse epitheliopathy in a cicatricial phase. Colour vision was also evaluated by 16 patients after central serous retinopathy. The results of this study are examined and discussed.

Adult↗