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Biomedical subjects

A Barberi

Publications and source records attributed to A Barberi.

At least 19 recordsLinked to original sources
PubMed2003

Myxopapillary ependymoma of the ischioanal fossa.

Ependymomas outside the confines of the cranium and spinal cord are rare. Direct extension into the soft tissues of the sacrococcygeal area may occur from a primary ependymoma of the spinal cord, cauda equina or filum terminale. Alternatively they may occur as a primary pre-sacral, pelvic and abdominal tumour, or as a primary tumour of the skin and subcutaneous tissue of the sacrococcygeal area without any demonstrable connection with the spinal cord. The Authors report a case of myxopapillary ependymoma of the ischioanal fossa, demonstrated by MRI. To our knowledge, our case is the first lesion reported at this site.

Ependymoma↗
PubMed2003

Prevalence and chemosusceptibility of Neisseria meningitidis and Haemophilus influenzae in a population of central Italy.

The purpose of this study was to determine the prevalence of nasopharyngeal carriers of Neisseria meningitidis and Haemophilus influenzae, and to evaluate their chemoresistance. N. meningitidis was more frequently isolated in adolescents (10-15 years). All of meningococci were susceptible to ceftriaxone and rifampin, only one isolate showed reduced susceptibility to chloramphenicol and four strains showed reduced penicillin susceptibility. The results show that these drugs are still effective for prophylaxis and treatment in our area. All strains of H. influenzae were susceptible to penicillin, ceftriaxone, chloramphenicol, rifampin, azithromicin and gentamicin. 6 nontypeable strains were resistant to sulfamethoxazole-trimethoprim, 7 strains of type a and c-f, and 3 non-typeable strains showed reduced susceptibility to tetracycline. In contrast with the current trend in the world, in our area the susceptibility of H. influenzae to betalactams was 100%, therefore these antibiotics are still the drugs of choice for treatment of invasive diseases.

Adolescent↗
PubMed2002

Case report. Ultrasound and CT findings in lipoma of the inferior vena cava.

Several cases of a fat mass-like lesion adjacent to and/or projecting into the inferior vena cava have been presented as a normal variant of perioesophageal fat distribution or as intravascular lipoma. We report a case of a lipoma of the inferior vena cava, studied with coronal reformatted CT images, ultrasound and colour Doppler imaging, in a 78-year-old female patient.

Aged↗
PubMed2001

Evaluation of PCR methods for 5S-rDNA and p30 genes to detect Toxoplasma gondii in blood and other clinical samples.

During the last few years the direct diagnosis of Toxoplasma gondii infection has taken advantage of PCR. The present work tested the sensitivity and specificity of PCR for rDNA and p30 genes. Using ascitic fluid from infected mice rDNA PCR detected 0.5 tachyzoite/ml, while nested p30 PCR 1 tachyzoite/ml. The rDNA amplification was positive in all clinical samples from a single immuno compromised patient (blood, urine and bronchoalveolar fluid). In the same patient nested p30 PCR was positive only in urine and bronchoalveolar lavage (BAL) fluid. The rDNA and p30 amplicons were never found in any amniotic fluids tested. These results could prove the usefulness of rDNA amplification to detect T. gondii in blood.

Amniotic Fluid↗
PubMed1989

Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only.

A total of 66.6% of Campylobacter pylori strains isolated from patients with peptic ulcers produced a cytotoxin active against mammalian cells in vitro, versus 30.1% of strains isolated from patients with chronic gastritis of various degrees of severity only. This difference was statistically significant and suggests that the toxic substance could be involved in the development of peptic ulcers.

Animals↗
PubMed1986

Prevalence, species differentiation, and toxigenicity of Aeromonas strains in cases of childhood gastroenteritis and in controls.

In a 1-year period (January to December 1984), Aeromonas strains were isolated from feces of 21 of 561 (3.7%) children with gastroenteritis and from 12 of 576 (2.1%) children without intestinal disturbances (controls). The difference between the two isolation rates was not significant (X2 = 2.2; P greater than 0.05). In five cases of illness other intestinal pathogens were isolated together with Aeromonas in the same stool sample. A total of 39 Aeromonas strains were detected since in some cases aeromonads with different biochemical characteristics were obtained from the same stool sample. Of the 39 Aeromonas isolates, 6 strains (5 from patients) were Aeromonas hydrophila, 5 strains (3 from patients) were Aeromonas sobria, and 26 strains (18 from patients) were Aeromonas caviae; 2 strains isolated from controls did not ferment sucrose and were considered a distinct group of Aeromonas. We found no significant difference between the prevalence of each of these species from patients and the prevalence from controls. We found no significant difference in the prevalence of enterotoxin-producing strains (suckling mouse model), cytotoxin-producing strains (HEp-2 cell model), or hemolysin-producing strains (rabbit erythrocyte model) between patients and controls. In our geographical region there is no evidence that Aeromonas species are primary intestinal pathogens in children.

Adolescent↗
PubMed1986

Viral childhood gastroenteritis.

Viruses were detected in 150 hospitalized subjects with gastroenteritis during the years 1983-1984. The samples were collected on admission in the day care unit and after three and seven days. The research was carried out using electron microscopy (E.M.) and isolation in cell cultures in vitro. Faecal samples were also collected from 70 control subjects. Observed and/or isolated viruses were identified by structural features at E.M. and by typical cytopathic effects in cultures. Rotavirus and not cultivable adenovirus proved the most widespread agents in the aetiology of acute viral gastroenteritis in infants.

Adenovirus Infections, Human↗
PubMed1985

Rubella in teenagers: epidemiology and prophylaxis in Siena, Italy.

Six hundred and fifty-three teenagers (aged 11-13 year) living in Siena and its surroundings (Tuscany, Italy) were the sample for serological screening intended to ascertain immunity to rubella. It was found that 324 of the teenagers (49.62%) lacked antibodies and, hence, were unprotected against the infection. Out of the 324 girls, 196 (around 3/5) were vaccinated using live vaccine. Post-vaccinal complications, with clinical signs of rubella infection, were recorded in almost one third of the vaccinees. Virus isolation from the blood was, in every case, not possible after either 10 or 30 days from vaccination. The serological findings, expressed in hemagglutination inhibition antibodies, could be summarized in the following way: (i) antibodies at low titre were found in only eight out of 184 girls (4.35%) ten days after vaccination; (ii) serological conversion was recorded in 187 out of 188 girls (99.47%) 30 days after vaccination; (iii) the titres were moderately high but much lower than those recorded for the natural infection. The results are discussed in the context of their implications for the strategies of rubella vaccination as far as the safety and the effectiveness of the vaccine are concerned, with emphasis on the duration of the protective immunity.

Adolescent↗
PubMed1977

[Effects of diphtheria and tetanus toxins on liver regeneration in the rat].

The effects of diphtheria toxin and tetanus toxin on the regenerating rat liver were studied. The following parameters were used: liver regeneration percentage, mitotic index, protein content and serum complement C3 fraction level. Diphtheria toxin does not affect the liver regeneration, that what confirms the poor sensitivity of the rat to this toxin. Tetanus toxin inhibits the cellular division, while causes an increase in the cell protein content, resulting in hepatocyte hypertrophy. Both toxins cause a fall of the serum complement C3 fraction.

Animals↗
PubMed1976

[The effects of staphylococcal alpha toxin on regenerating liver (author's transl)].

The effects of staphylococcal alpha toxin on regenerating liver of partially hepatectomized rats are studied. Sixty six rats are used. They are divided into three groups of twenty two animals each one. The first group included untreated animals, the rats of second and third group are injected with 0,1 UE of staphylococcal alpha toxin, respectively soon after hepatectomy (second group) and after twenty two hours (third group). As parameters we used: mitotic activity, percentage of hepatic regeneration, the contents of liver water and proteins. The results are: a low letality in all the animals, a lower mitotic activity in all treated animals than in the intact ones, the percentage of restoration, the contents of water and proteins are the same in all the animals of the three groups. The AA. conclude that staphylococcal alpha toxin has a little negative mitotic effect on partially hepatectomized rats liver.

Animals↗
PubMed1975

Effects of E. coli O 127 endotoxin on regenerating rat liver.

The Authors investigated the effect produced by endotoxin upon regenerating rat liver. The animals were divided into three groups after hepatectomy. The first group of animals received physiological solution, the second group received 0.5 mg of E. coli endotoxin soon after hepatectomy and the last group received the same quantity of endotoxin 22 hours after hepatectomy. To estimate hepatic regeneration we used: percentage of liver regeneration and mitotic activity. It was noted that the percentage of hepatic regeneration and mitotic activity were higher in the two groups of treated animals than in the control group. Mitotic activity and hepatic regeneration were higher in the animals treated 22 hours after hepatectomy than in the animls of second group. These results lead us to conclude that E. coli O 127 endotoxin is mitogenic also in vivo.

Animals↗