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Biomedical subjects

A Basse

Publications and source records attributed to A Basse.

At least 37 records · Page 2Linked to original sources
PubMed1989

Mycosis in the stomach compartments of cattle.

During a period of 22 months, 9.7% (23 out of 238) of the cattle necropsied at the Department of Veterinary Pathology had mycotic affections in the stomach compartments. The various stomach compartments were affected in the following pattern: omasum: 15 cases, rumen: 10 cases, reticulum: 8 cases and abomasum: 6 cases. In 5 of the animals mycotic affection was also found in other organs of which the liver was most often involved. Out of the 23 cases described, a primary diagnosis of mycosis was only established in 5 cases. In the remaining 18 cases the mycotic infection was regarded as being of a minor importance in the total necropsy result. Macroscopically and histologically the mycotic processes could be grouped into acute, subacute or chronic affections. In 20 cases only one type of inflammation was present, in the remaining cases combinations were found. Identification of the infective agent was performed by immunological staining of hyphal structures in tissue sections. Members of the Zygomycetes were found to predominate as causative fungi. Aspergillus fumigatus was found to have a propensity for infecting the terminal gastric compartments, whereas the Zygomycetes were found regularly in all compartments. Candida spp. were only found in 1 case. Predisposing factors for developing systemic mycosis are discussed. Among these especially the use of antimicrobial drugs, other diseases, metabolic disturbances and stressors in the post parturient period seem to be important.

Animals↗
PubMed1987

A murine model for the assessment of placental and fetal development in teratogenicity studies.

During normal pregnancy in the mouse, maternal serum levels of the analogues to human schwangerschaftsprotein-1 and alpha-fetoprotein correlate significantly with the growth of the placenta and fetus respectively. This relationship has been utilized in the analysis of the effect of sodium selenite on placental and fetal growth in mice. Moderate doses of sodium selenite did not affect the growth of the placenta and fetus significantly, whereas high doses of selenite resulted in a large percentage of abortions. The protein markers were found to be useful in the prediction of placental and fetal growth, and they are suggested to be of general use in the study of the impact of teratogenic substances, since they reflect the status of the fetoplacental mass during gestation.

Abnormalities, Drug-Induced↗
PubMed1987

Fertility in two cats with X-chromosome mosaicism and unilateral ovarian dysgenesis.

Two pregnant cats showed unilateral ovarian dysgenesis at surgery. Cytogenetic examination revealed a 37,X/39,XXX karyotype in Cat 1, a 37,X/38,XX karyotype in Cat 2 and a marked difference in frequency of mosaicism between fibroblasts and lymphocytes in both cats. Histologically the ovarian morphology ranged from normal to complete dysgenesis in both cats. Three fetuses examined showed a normal feline karyotype.

Animals↗
PubMed1984

Interdigitating cells in the lymphoid tissues of bovine fetuses and calves. An electron-microscopic study.

Electron-microscopic studies of lymphoid tissues from bovine fetuses and from calves disclosed a non-lymphoid cell type in the thymus-dependent zones of secondary lymphoid tissues and in the thymus that is distinguishable from reticulum cells, epithelial and endothelial cells, and macrophages. Based on morphological and topographical criteria, the cell is identified as the interdigitating cell. In addition, studies of the tissues of normal and virus-challenged fetuses, and of conventionally reared calves, indicated that the interdigitating cells originate from monocytoid cells, which undergo differentiation in the thymus-dependent zones during an immune response.

Animals↗
PubMed1983

Congenital tremor type AI: light and electron microscopical observations on the spinal cords of affected piglets.

The histology and ultrastructure of the spinal white matter from the dorsolateral funiculus of the third cervical segment was studied in normal control pigs and pigs whose dams were inoculated with the Weybridge congenital tremor strain of swine fever virus in early pregnancy. Only inoculated sows produced abnormal piglets. These showed congenital tremors and ataxia. The severity of clinical signs was related to the degree of spinal myelin deficiency. Morphologically this was quantified by determination of the thickness of myelin investing axons classed according to their diameter. In clinically affected pigs fewer axons were myelinated than normal. Though the myelin sheath thickness increased with increasing axon diameter in all pigs whether clinically normal or not, the increase was less in moderately affected and much less in severely affected pigs. The deficiency of spinal myelin was probably due to delayed or sub-normal myelination accompanied by paranodal myelin abnormalities, myelin degeneration and remyelination.

Animals↗
PubMed1979

A syndrome with lack of udder developments in a high-yielding Jersey herd.

A syndrome with lack of udder development in a high-yielding jersey herd is described. The syndrome first appeared in the herd about 10 years ago. To try to elucidate this syndrome the endocrine pattern visualized by serum estrogen (Fig. 1) and progesterone (Fig. 2) levels was followed in 12 parturient cows. One case of typical lack of udder development appeared and was followed up by slaughter and pathological and histological examinations (Fig. 3 and 4). Pedigree investigations indicated that genetics could be involved in the syndrome. The endocrine pattern observed combined with the lack of udder development seems to indicate a complex disorder in the hormonal regulation which trigger the maternal preparation and initiation of parturition.

Animals↗
PubMed1978

Congenital ataxia and tremor with cerebellar hypoplasia in piglets borne by sows treated with Neguvon vet. (metrifonate, trichlorfon) during pregnancy.

In 1976--77 The State Veterinary Serum Laboratory received new-born pigs which had shown nervous disorders immediately after birth. In all the cases the sows had been treated with Nevugon vet. (metrifonate, trichlorfon) during pregnancy. In the majority of the affected litters the morbidity and lethality were 100 per cent. Analysis of the breeding data from some of the herds suggested that the period during which the fetuses are sensitive is rather narrow, i.e., approximately from day 45 to day 63. The disease was reproduced experimentally and it was concluded that oral treatment of pregnant sows with Neguvon vet. about the middle of the gestation period can result in severe nervous disorders in the piglets. Clinically the disease is characterized by ataxia and tremor, and corresponding to that there is a pronounced hypoplasia of the cerebellum and also a reduction in the size of the spinal cord.

Abnormalities, Drug-Induced↗
PubMed1976

Congenital osteogenesis imperfecta in Charollais cattle.

An outbreak of an apparently new hereditary bone disease--congenital osteogenesis imperfecta--in six newborn half-sib Charollais calves is described. In many respects the clinical, pathological, radiological and genetical findings resemble the congenital osteogenesis imperfecta seen in man and sheep.

Animals↗