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Biomedical subjects

A Benchimol

Publications and source records attributed to A Benchimol.

At least 109 records · Page 6Linked to original sources

Variant angina pectoris. Pain and arrhythmias controlled after postoperative myocardial infarction.

A 30-year-old man with variant angina pectoris and ventricular arrhythmias had an angiographically demonstrable 60% obstructive lesion of the proximal left anterior descending coronary artery that was observed to progress to 100% during spasm. Control of pain and arrhythmia by pharmacologic means was unsuccessful. Aortocoronary saphenous vein-internal mammary coronary bypass was associated with an anteroseptal wall myocardial infarction and relief from both angina pectoris and arrhythmias. It is suggested that infarction of the ischemic myocardium played a role in the successful management of this case.

Adult↗

Relief of angina pectoris in patients with occluded coronary bypass grafts.

Thirty-two patients from a larger series of subjects undergoing routine postoperative evaluation of the aortocoronary saphenous bypass graft procedure were found to have one (20 patients) or all (12 patients) of the implanted grafts totally occluded. Such occlusion occurred in association with persistent postoperative subjective improvement manifested by a significant diminution or complete disappearance of angina pectoris. Postoperative myocardial infarction was documented in only seven cases, and the possibility of successful partial revascularization could be logically applied to only 20 of these 32 patients. Other suggested mechanisms for relief of angina pectoris in this setting are mentioned, although none is scientifically proved. It is concluded that (1) the marked subjective improvement documented in this population does not universally correlate with anatomic success and that (2) a diminution in the degree of angina pectoris cannot be clinically applied as a reliable indicator of postoperative graft patency.

Angiocardiography↗

Influence of pacemaker-induced tachycardia with A-V block on left ventricular blood velocity in man.

Phasic instantaneous left ventricular blood velocity was measured by radiotelemetry in 28 subjects with a Doppler ultrasonic flowmeter catheter during atrial pacing and induced A-V block Type I Wenckebach A-V block with conduction ratios of 9:8 or lower generally produced a stepwise reduction of peak left ventricular blood velocity in relation to shortened R-R intervals. Longer Wenckebach periods resulted in little or no blood velocity alteration during 1:1 A-V conduction. Those beats following a blocked atrial depolarization were associated with augmented blood velocities. In three subjects, bigeminal periods of 3:2 A-V block resulted in larger left ventricular blood velocities when compared with 2:1 A-V block, despite identical R-R intervals following the blocked P wave. This latter phenomenon was attributed to diastolic augmentation of left ventricular contraction following the second and hemodynamically ineffective beat during 3:2 A-V block. Three patients manifested true blood velocity alternation during second-degree A-V block and changing R-R intervals. The variations in peak left ventricular blood velocity observed during atrial pacing and A-V block are related to changing inotropic state and cycle length dependent alterations of left ventricular diastolic filling.

Adult↗

Comparison of the electrocardiogram and vectorcardiogram for the diagnosis of left atrial enlargement.

Standard 12 lead electrocardiograms (ECG) and Frank vectorcardiograms (VCG) were recorded in 21 consecutive patients with mitral valvular disease and angiographically documented left atrial enlargement. Comparative sensitivities for the detection of left atrial enlargement were: diagnostic, ECG = 6/21 (29%), VCG = 14/21 (67%); suggestive, ECG = 3/21 (14%), VCG = 2/21 (9%); non-diagnostic, ECG = 12/21 (57%), VCG = 5/21 (24%). It is concluded that the Frank atrial vectorcardiogram is superior to the standard electrocardiogram for the diagnosis of left atrial enlargement.

Adult↗

Bacteroides pericardial effusion and cardiac tamponade in a patient with chronic renal failure.

A 31-year-old woman with chronic renal insufficiency and recurrent pericarditis developed an enlarging cardiac silhouette and physical signs of cardiac tamponade. Cardiac catheterization demonstrated pericardial effusion with hemodynamic evidence of cardiac compression. At pericardial exploration, 1.5 L. of foul-smelling purulent material was removed from a distended pericardial sac. Cultures of both the exudate and pericardium revealed pure growth of Bacteroides fragiles. The patient was subsequently treated with intravenous chloramphenicol and has had an uncomplicated clinical course since that time. This represents the first reported case of cardiac tamponade secondary to culturally proved Bacteroides pericarditis in the setting of chronic renal insufficiency.

Adult↗

Phasic left ventricular blood velocity alternans in man.

With the use of the Doppler ultrasonic flowmeter catheter, phasic instantaneous left ventricular blood flow velocity was measured by radiotelemetry in 28 subjects during pacemaker-evoked pulsus alternans. Blood velocity alternation was more manifest at faster pacing rates. Four patients demonstrated diastolic blood velocity alternans at the mitral valve. Discordant right heart pressure and left ventricular blood velocity alternation was recorded in three subjects. In one such patient, rate-related shifts of concordant and discordant left ventricular blood velocity alternans occurred. Intermediate or variant forms of alternation, comprising weak and strong beats in a ratio of 2:1, were noted in two subjects. This study provides the first comprehensive description of left ventricular blood velocity alternans in man. The observed phenomena may be related to an altered inotropic state or to beat to beat variations in end-diastolic fiber length.

Adolescent↗

Advances in clinical vectorcardiography.

With use of the Frank lead system, still loop and timed vectorcardiograms were recorded in more than 5,000 patients sujected to complete right and left hear catheterization and selective coronary cine angiography. Data so obtianed demonstrated clincila superiority of the vectorcardiogram over the standard 12 lead scalar electrocardiogram. Specific advantages of the vectorcardiogram include (1) recognititin of undetected atrial and ventrcular hypertropy, (2) greater sensitivity in identification of myocardial infaraction, and (3) superior capability for diagnosis of multiple infaractions in the presnece of fascicular and burnany number of simultaneously recoreded electrocardiographic leadsfor the analysis of complex arrhythmias and beat to beat changes in intraventricula conduction. SINCE THE VALIDITY AND USEFULNESS OF THIS TECHNIQUE HAVE BEEN ESTABLISHED, IT SHOULD BECOME PART OF THE ROUTINE NONINVASIVE EVALUATION OF PATIENTS WITH CARDIOVASCULAR DISORDERS.

Adult↗

Retinal vascular lesions in two patients with prolapsed mitral valve leaflets.

Two patients with retinal vascular lesions had mid-late systolic clicks on cardiac auscultation, suggesting the diagnosis of prolapsed mitral valve. The first patient demonstrated an inferonasal arteriolar branch occlusion secondary to embolization; the second patient had a central vein occlusion with multiple hemorrhages, glial proliferative tissue, and retinal neovascularization. This report describes the association between the prolapsed mitral valve syndrome and retinal vascular lesions.

Arterial Occlusive Diseases↗