PubMed Health⌕ Search

Biomedical subjects

A Berman

Publications and source records attributed to A Berman.

At least 91 records · Page 5Linked to original sources
PubMed1981

Vascular response in halo of recent halo nevus.

The depigmented halo of a recently acquired halo nevus showed prominent erythema. Microscopic examination of a specimen from the halo showed dilatation of the dermal blood vessels, thickening of the vessel walls, and swelling of the endothelial cells; cellular infiltration was totally absent. Direct immunofluorescent studies on skin from the halo failed to show vessel, basement membrane, or intercellular fluorescence with IgG, IgM, IgA, C3, and fibrin. We conclude that the erythema in the skin of the depigmented halo is the result of dilated dermal blood vessels and that the mechanism of vascular dilatation is not associated with direct infiltration by inflammatory cells nor with immune complex formation. Erythema in the skin of the depigmented halo has not, to our knowledge, been studied previously.

Adult↗
PubMed1981

Effects of phyto-oestrogens on progesterone synthesis by isolated bovine granulosa cells.

The effects of phyto-oestrogens on progesterone synthesis by isolated bovine granulosa cells in vitro were assessed. Various concentrations (0.37-3700 nmol/1) of biochanin A, genistein or oestradiol were added to cultures of bovine granulosa cells and the consequent changes in progesterone synthesis were measured. The effects of alkali-soluble extracts of Rhodes grass (Chloris gayana) and fodder beet (Beta vulgaris, var.) were also examined. Another series of experiments tested the effects of genistein and oestradiol on the increase of progesterone synthesis brought about by the addition of LH to the culture medium. It was found that biochanin A and genistein increased progesterone synthesis by 40-50% when added in concentrations of 3.5 and 185 nmol/1 respectively. At higher concentrations of phyto-oestrogens greater than 176 nmol/1 for biochanin A and 1850 nmol/1 for genistein. Oestradiol showed similar effects: maximum stimulation of progesterone secretion occurred in the presence of 0.184 nmol/1; inhibition was found with concentrations of greater than 1.84 nmol/1. Extracts of Rhodes grass but not of fodder beet also showed biphasic effects. Both genistein and oestradiol in high concentrations (3700 and 3671 nmol/1 respectively) inhibited the increase in progesterone synthesis provoked by LH. The data indicated that phyto-oestrogens, like oestradiol, have a dose-related, biphasic effect on steroidogenesis in the isolated bovine granulosa cell system.

Animals↗
PubMed1981

Colitis in the elderly. A reappraisal.

The records of 81 patients with colitis whose symptoms began after the age of 50 years were analyzed to determine the importance of ischemia as a cause of colitis in this age group and to evaluate the accuracy of previous diagnoses. Patients were classified by clinical, roentgenological and pathologic criteria. A retrospective diagnosis of ischemic colitis was made in three-fourths of the patients, one-half of whom had original discharge diagnoses of ulcerative, Crohn's or nonspecific colitis. This study supports our belief that ischemia is the most common cause of colitis beginning in patients older than 50 years of age. Moreover, the incorrect diagnosis of idiopathic inflammatory bowel disease in a large proportion of these patients may explain why colitis has been reported to behave differently in the elderly than in the young.

Aged↗
PubMed1980

Involuting common warts. Clinical and histopathologic findings.

Patterns of regression in common warts were studied. Patients with multiple verrucae vulgaris lesions applied topical agents to the warts and were observed at regular intervals until the lesions disappeared. Regression took place without the warts turning black in all but one instance. All warts did not disappear simultaneously; some lesions persisted weeks after others had disappeared. Microscopic examination in five patients of a wart persisting after most had regressed demonstrated mononuclear cell infiltration, exocytosis, and degenerative epidermal changes. Failure to demonstrate cellular infiltration in regressing common warts in earlier studies was probably due to concentration on studying only warts that had turned black. The regression of some of the warts in patients with multiple common warts may serve as an indicator that involution is in progress. Utilization of this observation to recognize clinically the period of involution may make possible studies during the critical phase of the involutionary process.

Administration, Topical↗
PubMed1980

The thermoneutral temperature zone and seasonal acclimatisation in the hen.

1. Oxygen consumption, body temperature, respiratory frequency and respiratory water loss of White Leghorn x Rhode Island hens were measured for short periods at six air temperatures between 2 and 32 degrees C. The hens were kept between tests in an open shed. The experiments were carried out over 3 years. 2. The upper critical temperature (Tcu) was estimated by the air temperature at which: 1, respiratory frequency increased above 60 respirations/min and 2, body temperature increased by 0.3 degrees C above that at the lower critical temperature. These responses to the test temperatures were examined as a function of the acclimatisation temperature (Ta) represented by the mean daily temperature during experimental periods. 3. A seasonal change in Tcu was observed, which correlated with Ta(r = 0.836). The seasonal 10 degrees C change in the Ta brought about a 3 degrees C change in Tcu, compared with an 8.5 degrees C change in the lower critical temperature. 4. Thermoneutral temperature zone decreased with increasing Ta; the two critical temperatures tended to merge at a Ta of 32 degrees C. The latter probably represents an upper limit for acclimatisation to heat.

Animals↗
PubMed1980

Histologic changes in seborrheic keratoses after rubbing.

Seborrheic keratoses in five patients were rubbed and biopsied at varying intervals after injury. Microscopic examination revealed acute and chronic patterns of histologic change. Hemorrhage, hyalinization of dermal papillae, and necrosis of epithelial tips were conspicuous early changes. Specimens taken more than 48 h after rubbing showed a spectrum of changes which included: loss of epithelial mass, expansion and interconnection of keratin cysts, thinning of the epithelium, proliferation of epithelial strands from the residual epithelium, increase in size of epithelial cells, and evidence of hair follicle relationships including trichostasis spinulosa and, in one specimen, hair germ proliferation. Dermal lymphocytic infiltration was variable and only rarely involved the epithelium. These observations demonstrate a patterned response of the seborrheic keratosis to trauma, and also indicate a relationship between seborrheic keratosis and the hair follicle.

Biopsy↗
PubMed1979

Effect of diurnal or nocturnal heat stress on egg formation.

1. Mature laying hens were subjected to ambient temperatures sufficient to maintain body temperature of 43 degrees C for periods of 6 to 7 h during the day (eight periods) or the night (five periods). This did not reduce total daily food consumption. 2. The effect of heat stress during the day was mostly on egg-shell quality, being adverse and significant. During the night heat stress caused a significant decrease in egg production, its effect during the day was less marked in this respect. 3. Heat stress thus seems mostly to affect the early stages of shell formation, while its effect on egg production seems to depend on the time at which it occurs in relation to ovulation. 4. These results suggest that egg production is directly affected by heat stress; prolonged heat stress probably also acts indirectly, by suppression of food intake.

Animals↗
PubMed1979

Seasonal acclimatisation in the hen.

1. The oxygen consumption and body temperature of White Leghorn x Rhode Island Red laying hens, which were being kept in a semi-natural climate, were periodically measured for short periods at ambient temperatures between 2 and 32 degrees C in a suitable chamber. 2. A seasonal shift was observed in lower critical temperature (Tc) and thermoneutral oxygen consumption. The slope of the relationship between oxygen consumption and air temperature at less than Tc was not discernibly affected by season. 3. The seasonal shifts correlated best with mean daily outside temperature Ta) during the experimental periods; a seasonal decrease of 10 degrees C in Ta was associated with a decrease of 8.5 degrees C in Tc and a 12% increase in thermoneutral oxygen consumption. 4. The capacity to maintain body temperature stability at extremes of environmental temperature was improved by acclimatisation to heat.

Acclimatization↗
PubMed1979

Seborrheic keratoses and trichostasis spinulosa.

In 54 of 325 seborrheic keratoses, trichostasis spinulosa was found within the keratinous cysts and between papillomatous surface keratin, in addition to being present in contiguous hair follicles. Trichostasis in seborrheic keratoses and trichostasis spinulosa are both more frequent in older age groups. Trichostasis spinulosa represents a marker of vellus hair follicles and indicates that some seborrheic keratoses incorporate and may be partially derived from the cells of the infundibular portion of the follicle.

Adult↗
PubMed1978

Efflorescence of new warts: a sign of onset of involution in flat warts.

The sudden eruption of large numbers of tiny new warts in a patient with multiple flat warts often signals the onset of involution and subsequent regression of all flat warts. We have observed 5 such cases and, in this report, describe 2 cases in which the sudden efflorescence of many new warts was used as a sign to predict accurately the onset of involution and subsequent regression of all flat warts. Correlation of the histopathological and clinical findings provides an explanation for this phenomenon.

Adult↗
PubMed1978

Inflammatory seborrheic keratoses with mononuclear cell infiltration.

Inflammation in inflammatory seborrheic keratoses was found to be composed of mononuclear cells, particularly lymphocytes. Accumulations of mononuclear cells in the papillary and subpapillary dermis frequently showed no tendency to infiltrate the epithelium. However, dramatic interaction of the seborrheic keratosis and the inflammatory process also was common. The lymphocytic exocytosis into the epithelium followed two basic patterns: eczematous, characterized by intercellular and intracellular edema, microvesicle formation, and epithelial necrosis; and lichenoid, in which a bandlike infiltrate attacked the dermoepidermal junction and hyaline bodies occurred in the infiltrated epithelium and in the dermis. Epithelial changes consisted of necrosis of epithelial cells and related parakeratosis; squamous eddies were occasionally found. Inflammatory cell infiltration in seborrheic keratoses possibly represents a process other than irritation, and we propose that mononuclear cell infiltration in seborrheic keratoses may be related to an involutionary process.

Dermatitis, Seborrheic↗
PubMed1978

Metabolic rate: its circadian rhythmicity in the female domestic fowl.

1. In quasi-natural cyclic lighting, a circadian rhythm was observed in seven fowls; the range of oscillation of the rhythm was 50% of the mean metabolic level. Little variation was present between the individuals. 2. In fowls maintained for 15 days in isolation under 700 lx (ten fowls) or 0.07 lx (four fowls) constant lighting and at constant temperature free-running rhythms were evident; the range of oscillation was about 12% of the mean level. Large variation prevailed between the individuals in the range of oscillation and in the portion of variance accounted for by periodic regression. In dim light, rhythmicity declined to become non-significant by 8 days of exposure. 3. In four fowls maintained in a 6L/6D regimen for 12 days, metabolic rate was entrained to an ahemeral rhythm; there was no evidence of circadian influence on the metabolic response to light. Little variation was present between the individuals. Rhythmicity was maintained over the experimental period. 4. Metabolic levels were similar on 0.07 lx, 700 lx constant light, during the dark phase of the 6L/6D regimen and during night time in the quasi-natural cyclic lighting. They were also similar on the light phase of the 6L/6D regimen and the quasi-natural lighting.

Animals↗
PubMed1978

Failure of flat warts to recur in electrosurgically altered skin.

Two men with recurring flat warts in the beard area have been observed for five and ten years, respectively. Both have depigmented patches at sites where flat warts had been removed by electrosurgical destruction. Crops of new warts appear periodically. These develop always on the normally pigmented skin and have never been found in the leukodermic areas. Flat warts have been observed repeatedly at the margin of depigmented and normal skin; these invariably enlarge toward the normal skin and never encroach on leukodermic skin. The failure of flat warts to develop in electrosurgically treated skin, if substantiated, would indicate that local tissue factors influence resistance to development of flat warts. Perhaps this phenomenon is similar to that reported in Darier's disease, where partial-thickness excision of involved skin has resulted in resistance to recurrent disease.

Electrosurgery↗