Biomedical subjects

A Cila

Publications and source records attributed to A Cila.

42 records · Page 3Linked to original sources

PubMedDate not supplied

Pleuropulmonary blastoma in a child presenting with pneumothorax.

Pleuropulmonary blastoma is an uncommon primary malignant tumor of the lung. Surgery is the most important part of the treatment. Despite the use of chemotherapy with or without radiotherapy, the prognosis is poor. Here we report on the case of a 2.5 year-old boy presenting with pneumothorax who turned out to have a right hemithoracic mass. The patient underwent surgical resection of the mass. Pathologic diagnosis was type II pleuropulmonary blastoma. Postoperative thoracic CT showed nodular residual densities so the patient was given adjuvant combination chemotherapy with cisplatin and etoposide. He has been disease free for 12 months.

Child, Preschool↗

PubMedDate not supplied

Measurement of vertebral rotation in standing versus supine position in adolescent idiopathic scoliosis.

Thirty-three structural curves of 25 patients with adolescent idiopathic scoliosis were evaluated using computed tomography (CT) scans and plain radiography. The average Cobb angle on standing radiographs was 55.72 degrees and was observed to be corrected spontaneously to 39.42 degrees while the patients were in supine position (29.78% correction). Average apical rotation according to Perdriolle was 22.75 degrees on standing radiographs and 16.78 degrees on supine scanograms. The average rotation according to Aaro and Dahlborn on CT scans was 16.48 degrees. Radiographic measurements were significantly different from axial CT slice or scanogram measurements (p = 0.000), but the two latter measurements, both obtained in the supine position, did not appear to be different (p = 0.495). Deformities on the transverse plane as well as on the coronal plane are influenced by patient positioning. If the patient lies supine, the scoliosis curve corrects spontaneously to some degree on both planes. Measurements obtained from the scanograms by the Perdriolle method in the supine position are very similar to those obtained by CT. Perdriolle's is a simple, convenient, and reliable method to measure rotation on standing radiograms.

Adolescent↗

PubMedDate not supplied

Diagnostic value of computed tomography in spinal and lateral recess stenosis, preoperatively and for long-term follow-up: a prospective study in 50 cases.

Preoperative measurements of lateral recess, anterior-posterior diameter of the spinal canal and interpedincular distance were made in 50 patients with low back pain. The results were compared with the surgical findings. The patients were followed up for two years. CT findings and clinical results were evaluated to determine whether preoperative CT could provide any evidence of failed spinal surgery in patients with recurrent symptoms.

Adult↗

PubMedDate not supplied

Methotrexate-induced leukoencephalopathy. A case report.

A six-year-old girl with non-Hodgkin's lymphoma who was treated with both intravenous (IV) and intrathecal (IT) methotrexate and developed brain damage secondary to the cytostatic drug is described. This patient displayed hypertension, hypothermia/hyperthermia, lethargy, deterioration and coma as clinical findings, and bilateral, focal white matter hyperintensities in the occipital lobes were seen in her magnetic resonance imaging (MRI). Treatment-related leukoencephalopathy is one such adverse effect of IT methotrexate administration on the central nervous system and usually appears in a generalized form.

Antimetabolites, Antineoplastic↗

PubMedDate not supplied

Computed tomography and angiographic findings of childhood moyamoya disease.

Moyamoya disease is a rare entity consisting of bilateral stenosis or occlusion of internal carotid arteries with abnormal collateral vessels at the base of the brain. We present five Turkish children with this disease, which is more common in Japan. Focal neurologic deficits and/or epilepsy were the common presenting symptoms in two girls and three boys between the ages of 1.5 and 11 years. Multiple cerebral infarcts were diagnosed in all of the cases by Computed Tomography (CT). Abnormal net-like vessels at the base of the brain were detected in three patients. Cerebral angiography, which is necessary to confirm the diagnosis, showed moyamoya vessels and bilateral stenosis or occlusion of the internal carotid arteries in all cases. Although the angiographic staging was advanced in three patients, neither clinical status nor parenchymal abnormalities detected with CT were different from the other two cases.

Angiography, Digital Subtraction↗

PubMedDate not supplied

Magnetic resonance imaging (MRI) findings in isolated growth hormone deficiency.

In this study the presence of pituitary-hypothalamic abnormalities was searched by magnetic resonance (MR) imaging in 30 children (18 males and 12 females, aged 7.4 to 23 years) with isolated growth hormone deficiency (IGHD). Small anterior pituitary was demonstrated in 18 patients and ectopic posterior pituitary (EPP) in four of them. Pituitary stalk was found to be thin in two patients with anterior pituitary hypophasia and EPP and was visible only in post-gadolinium images. In one patient, a hypothalamic mass was found and the bright spot of the posterior pituitary was found without diabetes insipidus, possibly due to a variation in the intensity of the bright signal. Eight patients had normal pituitary imaging suggesting functional damage. In all five patients with familial growth hormone deficiency the anterior pituitary was hypoplastic. We conclude that a high percentage of patients with IGHD had anomalies of the hypothalamo-pituitary region, which could be demonstrated by MR imaging. Furthermore, the low frequency of perinatal abnormalities in these patients suggested developmental defect as the cause of the morphostructural abnormalities. The presence of the familial cases with the same defect pointed to the genetic origin in some instances.

Adolescent↗