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Biomedical subjects

A Criado

Publications and source records attributed to A Criado.

At least 37 records · Page 2Linked to original sources
PubMed1995

[Latex allergy in anesthesiology].

Allergy to latex, described 15 years ago, is increasing. It affects mainly certain risk groups, such as health-care workers and patients with spina bifida or genitourinary malformations. Symptoms vary in intensity from mild to life-threatening and can present during any medical procedure involving skin or mucosal contact, or inhalation, of the allergen in a previously sensitized patient. The most serious cases reported have generally involved patients undergoing surgery. Prevention is based mainly on tentative diagnosis made when the patient's history is taken, followed by laboratory tests and consultation with an allergist. Because prophylactic drug protocols have proven ineffective, the patient must be offered a latex-free environment in keeping with standard recommendations.

Allergens↗
PubMed1995

[Electromyographic response to precurarization with vecuronium bromide].

OBJECTIVE: To analyze electromyographic response and clinical effects after precurarization with vecuronium bromide (0.01 mg/Kg), also noting intubation conditions and the presence or not of fasciculations after administration of succinylcholine (1.5 mg/Kg). PATIENTS AND METHODS: A single precurarization dose of vecuronium was administered to 20 patients 5 minutes before anesthetic induction for general surgery. During this period we monitored neuromuscular transmission of the cubital nerve in the wrist by electromyography with a series of 4 stimuli, expressing each as the percentage of the first response and of the ratio T4/T1. We also recorded clinical repercussions. General anesthesia was then induced; after administration of succinylcholine, the presence or not of fasciculations was noted and intubation conditions were evaluated. RESULTS: The electromyographic response after precurarization was highly variable, as 4 different responses were recorded. We found potentiation phenomena in 20% of our patients, diminished response in 60%, fatigue phenomena in 15% and no change in 5%. Clinical signs noted were blurred vision and heavy eyelids. Fasciculations disappeared in 95% of the patients and intubation conditions were excellent. CONCLUSIONS: Vecuronium at a precurarization dose produces highly varied but well-tolerated electromyographic responses. The drug is effective in eliminating fasciculations produced by succinylcholine and does not affect intubation conditions.

Adult↗
PubMed1993

Anthelmintic activity of pyrazinothiadiazine dioxide derivatives.

In a search for new anthelmintic compounds, some pyrazinothiadiazine dioxide derivatives were synthesized. Their anthelmintic activity was tested against larva and preadult stages of Trichinella spiralis. The mode of action and acute toxicity of these compounds were investigated. Structure-activity relationships are discussed.

Animals↗
PubMed1992

Viability of Echinococcus granulosus cysts in mice following cultivation in vitro.

The viability of hydatid cysts developed in vitro for 90 days was assessed by implantation into mice. Cysts removed from mice at 270 days post-infection (p.i.) increased their size 13.5-fold and contained several brood capsules containing protoscoleces. Thus, cysts remain viable after prolonged in vitro culture. The implantation in mice of 15 cysts developed in vitro yielded an average of 10 cysts per mouse, which is indicative of a high survival rate in these experimental infections. The ultrastructural study of cysts recovered from mice 270 days p.i. showed that the germinal membrane was more compact than before implantation and several layers of tegumental cells had developed. Observations of cysts removed from mice indicated that the plasma membrane surrounding microtriches had prolongations opening into the laminated layer.

Animals↗
PubMed1990

[Socioeconomic factors: do they influence the demand for care and the degree of satisfaction in primary care?].

A survey of 248 individuals was carried out. They included both males and females aged between 16 and 80 years, and they were selected as a representative sample of the population on care in the health center "Huerta de la Reina" for an error margin of 5% and p less than 0.05. The possible influence of cultural and socioeconomic factors on the opinion of the population about the received attention and the degree of use of health care services was evaluated. 76.2% of our patients are not working, 68.5% are females and 57% are older than 46 years. These two groups show the highest rate of consultation for administrative purposes. The educational level, profession, sex, age and the district of origin do not influence the evaluation of the received care. The patients from the quarter with the lowest socioeconomic status consider that the physician pays less attention to them and have a poorer understanding of the latter's explanations (p less than 0.05). Both factors exert an influence on the evaluation of the new model of care. It was concluded that the socioeconomic characteristics of a population are very important for the development of an integrated type of attention by primary care teams.

Age Factors↗