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Biomedical subjects

A E Radzevich

Publications and source records attributed to A E Radzevich.

33 records · Page 2Linked to original sources
PubMed1986

[Contrast echocardiography using hydrogen peroxide].

The practicability of using hydrogen peroxide solutions for contrast echocardiography was examined. The administration of 1-3 ml of 0.2% solution mixed with a drop of the patient's blood, into the cubital or catheterized subclavian vein produced intensive and lasting (up to 2 min) contrast of the right cavities of the heart. Cubital injection of the solution was associated with a more lasting effect, as compared to the subclavian administration. The causes of this difference are yet to be investigated. The contrasting effect was fairly persistent and marked even when concentrations of the hydrogen peroxide solutions were reduced to 0.15 or 0.1%. The rate of administration was not more than 1 ml/s and had no negative effect on the quality of the contrast. No side effects associated with repeated administration of 1-3 ml hydrogen peroxide solution in the above-mentioned concentrations were noted in either of the 20 patients thus examined.

Contrast Media↗
PubMed1985

[Effect of nitroprusside, nitroglycerin, propranolol and mannitol on the size of a myocardial infarct].

Effects of nitroprusside, nitroglycerin, propranolol and mannitol on the size of infarcted and peri-infarction areas were examined in 276 patients with acute left-ventricular anterior myocardial infarction. The study involved an assessment of electrocardiograms from 35 precordial leads, and the measurement of central venous blood pressure, hemodynamic parameters, serum enzymes, acid-base state and, in some patients, the pressure inside the pulmonary artery, right and left cavities of the heart and the aorta, left-ventricular kinetocardiography, etc. All the drugs examined were shown to have a favourable effect on the size of the peri-infarction area and reduce the extent of myocardial infarction. Indications for each of the drugs have been worked out on a differential basis. A detailed analysis of ECG patterns from multiple chest leads under the action of nitroprusside, nitroglycerin, propranolol and mannitol is presented.

Cardiac Catheterization↗
PubMed1984

[Use of sodium nitroprusside in patients with acute myocardial infarct complicated by left ventricular failure].

Fifty-six patients with acute myocardial infarction aggravated by left ventricular insufficiency were examined. A series of 39 patients received the intravenous instillation of sodium nitroprusside, the remaining 17 patients were given conventional treatment. Hemodynamic parameters and those yielded by precordial mapping at 35 leads were compared over time between the groups. Sodium nitroprusside therapy was related to significant beneficial changes in the hemodynamic parameters and ECG. It is concluded that sodium nitroprusside is highly effective in controlling left ventricular insufficiency in patients with acute myocardial infarction.

Adult↗
PubMedDate not supplied

[Orthostatic tolerance and the status of central and peripheral hemodynamics during 7-day "dry" immersion in persons with neurocirculatory asthenia of the hypertensive type].

Eleven healthy male volunteers, aged 45-55 years, with neurocirculatory dystonia of the hypertensive type were exposed to 7-day dry immersion. The following parameters were measured: central and peripheral hemodynamics (by the method of rheography), linear blood flow velocity, and orthostatic tolerance before and after immersion. During an acute period of adaptation to immersion the test subjects developed: centralization of blood filling of the head and lungs, decrease of stroke volume and cardiac output, increase of linear blood flow velocity in forearm arteries and its decrease in leg arteries, drastic decline of orthostatic tolerance.

Adaptation, Physiological↗
PubMedDate not supplied

[Cardiosynchronized means of treatment and diagnosis].

Diverse ways of a cardiophased action on the cardio-vascular system for therapeutic and diagnostic purposes are assessed. Requirements for the basic subunits of the assisted circulation apparatus to be met, the possibilities open for developing automatic cardiosynchronization systems, and also features peculiar to the synchronization mode in effecting coronarography and conditions necessary for implementation of the method for elective introduction of liquid agents into the supravalvular space of the aorta are discussed.

Assisted Circulation↗
PubMedDate not supplied

[Effect of positive pressure breathing on hemodynamics in patients with borderline arterial hypertension during water immersion].

Patients with borderline hypertension were exposed, while being immersed, to positive pressure breathing. During exposure cardiac output (CO), heart rate (HR), mean arterial pressure (MAP), total peripheral resistance (TPR), left ventricle work (W), blood content of head vessels (Qh), upper and lower lung lobes (Qu1 and Q11), liver (Q1) were measured. During immersion CO and MAD decreased, HR and TPR increased slightly, and W diminished. Simultaneously Qh, Qu1 and Q11 increased significantly while Q1 decreased considerably, indicating blood "centralization" during simulated microgravity. Courses of positive pressure breathing led to decreases in Qh, Qu1, Q11 and increase in Q1, i. e., they caused blood to be displaced from the head and lungs to the liver. Thus, the liver plays the role of a physiological pool which accumulates blood removed from the upper body by positive pressure.

Cerebrovascular Circulation↗
PubMedDate not supplied

[Effect of water immersion on indices of central hemodynamics in subjects older than 45 years].

The effect of 7-day dry immersion on central hemodynamics of four test subjects, aged 46, with boundary arterial hypertension was investigated. The controls were two healthy men, aged 24. Central hemodynamics was examined by integrated rheography. Variations in blood pressure, central venous pressure, stroke and cardiac indexes, heart rate and total peripheral resistance were measured. The control subjects showed a decrease of blood pressure during exposure (P less than 0.01). Two of the test subjects with a short history of boundary arterial hypertension displayed similar variations (P less than 0.01), whereas two others showed an increase of blood pressure during the immersion period (P less than 0.01). The test and control subjects did not exhibit significant differences in the stroke and cardiac indexes, heart rate, central venous pressure or total peripheral resistance: stroke and cardiac indexes decreased while central venous pressure and total peripheral resistance increased, and heart rate remained unchanged.

Blood Pressure↗