[Comparative effect of sodium salicylate and other structural isomers of oxybenzoic acid on antibody titre and functional groups of proteins].
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Biomedical subjects
Publications and source records attributed to A F Leshchinskiĭ.
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Body exposure to the physical therapeutic factor (skin applications of heated peloid) leads to the acceleration of hydroxylase reactions proceeding on cytochrome P450. This circumstance determines the speeding up of the biotransformation of a number of pharmacological agents (strychnine, aniline, amidopyrine, etc.), and changes in the action of some drugs (phenobarbital, amidopyrine,, ethazole) affecting the drug-metabolizing microsomal system.
Pathogenic influence of Chernobyl-related factors was modelled with the view to study peculiarities of changes in the most important systems of the body induced by long-term low-dose ionizing radiation associated with hypo- and hyperthyroidism. Experimental rehabilitative therapy stipulated following methods of physico-pharmacological treatment: 1) course of general electrophoresis with chemical components of peloids; 2) the same course with Ethimisol added to the solution used for electrophoresis. Clinical follow-up of patients resided in the Chernobyl-stricken territories proved advisability of differentiated application of aforementioned methods according to prevailing thyroid symptoms.
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