Additional factors linking corneal melting to topical nonsteroidal anti-inflammatory drugs.
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Biomedical subjects
Publications and source records attributed to A Flach.
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The authors compared 105 patients who met DSM-III criteria for bulimia with 86 control subjects on measures of family environment and presence of eating disorders. Bulimic patients' perceptions of their families included low cohesiveness, a lack of emphasis on independent and assertive behavior, and a high level of conflict coupled with a low emphasis on open expression of feelings. Families of bulimic subjects had achievement expectations comparable to those of control families, but the former placed less emphasis on intellectual and recreational activities. The high disorganization of the families of bulimic subjects was associated with severity of symptoms.
Correction of the female external genitalia of children with intersex should, if possible, depend on the problems of individual sensibility. Several published methods and an operation devised by us are described with consideration of possible later decisions made by the patient.
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Malignant ovarian tumours in childhood are rare. Germinal cell tumours are the most common tumours and are extremely malignant, with the exception of dysgerminomas. The possibilities of therapy have improved considerably in the last 3 to 4 years, thanks to combined chemo- and radiotherapy following surgical resection of the tumour. Exact staging at the beginning of therapy is very important. A second operation, primary or as a second look procedure, is recommended after emergency operations. Therapy should be carried out in pediatric oncology centres. Because of the invasive measures, medical and psychological care are necessary after the conclusion of therapy. The rarity of these tumours should prevail upon us to organize national and international therapeutic studies.
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38 children between 5 and 14 years of age with juvenile bone cysts were followed up to a maximum of 20 years. In two-thirds of the cases the diagnosis was made on the occasion of a fracture in the cyst region. One child received conservative treatment, 37 children were operated on. The roentgenological diagnosis of all children operated on was confirmed histologically. The operative procedure consisted in milling out the cysts and filling the cavities with autogenous, allogenous or xenogenous spongiosa. Because of the high recurrence rate (10-40% in the literature and 19% from our own experience) we suggest a modified surgical procedure assuring complete recovery. Subtotal diaphysectomy with interposition of a corticospongious splinter and allogenous spongiosa using a stable osteosynthesis in the case of large primary cysts in metadiaphyseal position is discussed.
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A 35-year-old man demonstrated sulfisoxazole diolamine-induced photosensitivity during treatment for staphylococcal blepharitis. This reaction was easily avoided by applying the ointment at bedtime and covering the eyelids during sun-bathing while in therapy. A drug-induced photosensitivity reaction should be considered in cases of staphylococcal blepharitis resistant to or aggravated by eyelid-margin therapy with sulfonamides.
The features of malrotation of the intestine, include the incomplete fixation of the mesentery which may lead to torsion in association with abnormal positioning of the cranial mesenteric vessels. There are also abnormal strangulated peritoneal bands extending from the large bowel across the duodenum. These anomalies can either lead to duodenal obstruction or to volvulus. The operative procedure described by Ladd has the advantage that it is brief but requires relatively frequent repeat laparotomies. Complete correction with the attempted construction of normal anatomy has the disadvantage that it is a difficult and time-consuming procedure, but the incidence of repeat laparotomy is significantly lower. It is therefore suggested that "at risk" children may be preferably treated by the Ladd procedure and this should always be used if there are anaesthetic problems.
16 cases of mesenteric caval anastomosis in children with recurrent bleeding from oesophageal varices are presented. Advantages of this technique include the quick normalisation of portal pressure and the low incidence of thrombosis or recurrent bleeding. This complication arises in 10% of patients treated with a central mesenteric caval shunt. The disadvantage of the technique presented is the reduction of perfusion of the liver and the necessity of ligating the iliac veins. An alternative procedure is spleno-renal shunt but this also leads to a reduction of liver perfusion. An alternative procedure is spleno-renal shunt but this also leads to a reduction of liver perfusion. The incidence of thrombosis and recurrent bleeding is higher using this method and on the whole the choice of technique is determined by the age of the patient.
3 patients with solitary, non-parasitic cysts of the liver are reported. 2 of these were seen in infants and one in a 7 year old child. The clinical presentation, diagnosis and treatment are discussed. Complete excision of the cyst is the treatment of choice and the various operative procedures described in the literature are discussed. The macroscopic and microscopic findings of these cysts are described.
The value of scintigraphic examinations of injuries involving the epiphyseal plate is to be seen to ensure the correct diagnosis of the lesions type I and type V according to Salter and Harris. Further on the results of these scintigraphic examinations allow a better planning of the therapeutic procedure. Experimental findings in rabbits succeeded to predict the seriousness and an early prognosis. The disturbances of the epiphyseal blood flow can be diagnosed by 99m Tc-O4 labeled erythrocytes and 99m Tc-O4 labeled albumin microspheres. 99m Tc-MDP skeletal scintigraphy gives the information at which time the repair is done and full weight bearing is possible.