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Biomedical subjects

A Friesen

Publications and source records attributed to A Friesen.

At least 19 recordsLinked to original sources
PubMed2003

[European Association of Urology guidelines on urinary and male genital tract infections].

Today, the classical bacteria that cause venereal diseases, e.g. gonorrhea, syphilis, chancroid and inguinal granuloma, only account for a small proportion of all known sexually transmitted diseases (STDs). Other bacteria and viruses as well as yeasts, protozoa and epizoa must also be regarded as causative organisms of STD. Taken together, all sexually transmitted infections comprise more than 30 relevant STD pathogens. However, not all pathogens that can be sexually transmitted manifest diseases in the genitals and not all infections of the genitals are exclusively sexually transmitted. Concise information and tables summarising the diagnostic and therapeutic management of STDs in the field of urology allow a synoptic overview, and are in agreement with the recent international guidelines of other specialist areas. Special considerations (i.e. HIV infection, pregnancy, infants, allergy) and recommended regimens are presented.

Disease Notification↗
PubMed2000

[Aorto-mesenteric artery compression syndrome].

INTRODUCTION: The aim of this paper was to describe a rare gastrointestinal motility disorder caused by vascular compression of the duodenum. PATIENTS: The authors present two patients with vomiting and severe weight loss. Diagnostic evaluation revealed superior mesenteric artery syndrome. METHODS: After frustrane treatment with i.v. infusions, surgical intervention with laterolateral duodenojejunostomy or Roux-en-y reconstruction for restoration of the intestinal passage was performed. RESULTS: Following initial recovery, the first patient showed permanent anorexia. Psychosocial evaluation revealed a severe pathological mother-child relationship. Intensive psychological treatment finally achieved definite weight gain and complete recovery in this patient. The second case subsequently gained weight without psychological evaluation. CONCLUSION: The authors review the literature, pointing out the anatomy of the duodenojejunal angle, the etiology, and the predisposing factors, as well as diagnostic and therapeutic strategies.

Adolescent↗
PubMed1995

[Therapy of candiduria by alkalinization of urine. Oral treatment with potassium-sodium-hydrogen citrate].

METHOD: Eighteen hospitalized patients with candiduria were treated with oral potassium-sodium-hydrogen citrate to alkalinize the urine. The results obtained were compared with those observed in an untreated retrospective control group. Dosage was adjusted in accordance with the pH of the urine measured immediately before treatment with the aim of achieving a pH of 7 to 7.5. RESULTS: All patients had an indwelling catheter, which is a predisposing factor for candiduria. In 16 out of 18 patients (89%) treatment with potassium-sodium-hydrogen citrate raised pH and resulted in the disappearance of candiduria. Duration of treatment varied between two days and one month (mean: seven days). In four patients the urine became completely sterile; during treatment 12 out of 18 patients developed significant bacteriuria (in eight cases of these the indwelling catheter had been left in place). CONCLUSIONS: Alkalinization of the urine is a simple and effective method of treating candiduria in patients with an indwelling catheter. An additional advantage is the metaphylaxis and prophylaxis of renal stone formation in immobilized patients.

Acid-Base Equilibrium↗
PubMed1990

Transprostatic selective cystectomy with an ileal bladder.

Since 1987 we have changed our surgical approach to radical cystectomy and ileal neobladder in order to maintain erectile function and urinary continence. The routine diagnostic work-up includes a staging transurethral resection of the prostate in order not to miss any ductal involvement. The selective cystovesiculectomy is performed by cutting through the apex of the prostate, thus leaving a wide, funnel-shaped tunnel of the prostatic urethra for the anastamosis with the M- or W-shaped ileal reservoir. The preliminary results of 27 patients show excellent results concerning erectile function and continence, as requested by our predictive criteria. Especially the continence achieved after a training period of 3 months is reliable. Further observation will show whether the functional improvements and advantages in the operative technique are achieved at the cost of a higher relapse rate of urethral tumors.

Carcinoma, Transitional Cell↗
PubMed1989

[The dysuria syndrome. Significance of urethral diameter for recurrent bacterial cystitis in the female].

Internal urethrotomy is still used in female patients for the prophylactic treatment of recurrent bacterial cystitis as well as for sterile dysuric voiding disorders. 72% of the bacterial cystitis group (n = 18) remained uninfected during the 1st year after the treatment. 60% of the women with sterile dysuria complaints reported a significant improvement after the surgical procedure. The success is most possibly due to improved urodynamic conditions. The necessity of urethrotomy in patients with recurrent bacterial cystitis is discussed. The etiology of sterile dysuric voiding disorders however remains unclear.

Adult↗
PubMed1988

[The cadmium content of human tissues from biopsies].

The level of cadmium (cd) concentration was determined in organs of 130 men and women. This study was conducted on living human beings who, in their occupation, haven't had extraordinary cd-exposure. Samples of tissues taken during operation were evaluated as well as urine samples (24 hours specimen), blood, an extended patient history including occupation and the postoperative diagnosis. The average cd-concentration was means = 27.3 +/- 29.7 micrograms/g wet weight in kidney cortex, 9.3 +/- 11.7 micrograms/g in kidney medulla, 1.1 +/- 0.5 micrograms/g in liver, 2.9 +/- 2.5 micrograms/l in blood and 2.6 +/- 2.9 micrograms/l in urine. Concentrations in 7 other tissues were measured. The critical cd-level for liver and kidney was not reached in any case. Cd-concentration is related to age and cigarette smoking, not to the sex of the person. It is quite impossible to make a precise estimation on the kidney load from blood or urine level of an individual patient. Differences in cd-load between patients with cancer and those without are discussed. A synopsis of international studies shows that results achieved through various methods, radiological cd-measurement, autopsies and our biopsies were comparatively the same.

Adolescent↗
PubMed1984

[Nephrolithiasis--correlation of calculus type and pathogen spectrum. Calculus analysis and microbiologic diagnosis in 173 surgically treated patients].

The microbiological findings from intraoperative swabs were correlated with the consistency of the calculi in 173 patients, who had been operated on due to nephrolithiasis. The following parameters were taken into consideration: age and sex of the patients, consistency of calculi and germ spectrum of intraoperative swabs from the upper urinary tract. Three main groups were formed corresponding to the consistency of the calculi (carriers of infection calculi, of calciumoxalate calculi and of uric acid calculi) and these were compared to one another regarding the above mentioned parameters.

Bacteriological Techniques↗
PubMed1984

[Co-trimoxazole concentration in the prostatic fluid of patients with subacute and chronic prostatitis].

Plasma and prostatic fluid (PF) concentrations of co-trimoxazol (TMP/SMZ) were investigated on 16 patients with subacute or chronic prostatitis. Co-trimoxazol-forte was given perorally, 2X 1 tablet (2X 160 mg TMP/800 mg SMZ), daily. TMP-concentrations in PF were 3.3 micrograms/ml and 2.6 micrograms/ml three and six hours after peroral application (days two and three) respectively. Compared to the concentrations of TMP in plasma, there was an increase by the factor 2.0-3.7. The corresponding concentrations of SMZ in PF were 7.7 micrograms/ml and 10.4 micrograms/ml 3 and 6 hours after medication--i.e. 32% of the plasma concentrations.

Administration, Oral↗
PubMed1984

[The significance of Chlamydia trachomatis in chronic infectious urethro-adnexitis in the male].

The causative significance of chlamydia trachomatis in chronic urethra-prostatitis can be assumed because of the high incidence in non-gonorrheal and post-gonorrheal urethritis and epididymitis. 158 men with chronic inflammatory urethro-prostatitis were reviewed. In 32.3% the urethral smear and in 29.7% the prostatic fluid were positive for chlamydia trachomatis. Simultaneously leucocyte count and pH of the prostatic fluid as well as the immunoelectrophoresis of the ejaculate were investigated. The correlation of these results with positive chlamydia trachomatis findings demonstrates the significant role of chlamydia trachomatis in chronic inflammatory processes of the urethra and prostate.

Adult↗
PubMed1984

[Doxycycline in the treatment of non-specific urethritis and/or prostatitis].

Twenty-five men with non-specific urethritis/adnexitis were treated with 200 mg doxycycline monohydrate daily (Vibramycin Tabs) over a period of 10 days. More than half of the patients suffered from chronic inflammations. Microorganisms isolated from urethral secretion and prostate exprimate comprised aerobes, in particular staphylococcus epidermidis and streptococcus faecalis, as well as mycoplasmae, chlamydiae, and anaerobes, mainly bacteroides species and peptostreptococci. Fourty percent of patients additionally had anatomical alterations such as constrictions or strictures of the lower urinary tract. After 10-day therapy with doxycycline 16 out of 24 patients (67%) could be cured and a further six patients (25%) could be improved. Microbiological cure could be achieved in infections with chlamydiae in all cases, in infections with mycoplasmae in 67%, in infections with anaerobes in 80%, and in infections with aerobes in 57% of cases. Overall, the therapeutical success in the investigated patient population with chronic infections which are difficult to treat has therefore to be regarded as excellent. Therapy had to be discontinued in one patient after 3 days due to diarrhoea and nausea. In the other patients toleration of doxycycline was good.

Adolescent↗
PubMed1982

[Renal sinus lipomatosis, a pseudotumorous transformation].

A case of longstanding chronic pyelonephritis associated with severe recurrent nephrolithiasis followed by excessive lipomatosis, ureteritis cystica and xanthogranulomatous pyelonephritis is presented. In addition to the definition and morphologic description of lipomatosis its differential diagnosis is discussed. This also applies to the pathogenesis of these diseases. The special role of lipomatosis in the perpetuation of a circulus vitiosus is stressed. In special cases it seems to be justified to speak of clinical malignant lipomatosis.

Female↗