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Biomedical subjects

A Friesen

Publications and source records attributed to A Friesen.

28 records · Page 2Linked to original sources

[Co-tetroxazin levels in the prostatic secretion of patients with subacute and chronic prostatitis].

Plasma and prostatic fluid concentrations of co-tetroxacine (TXP/SDZ) were investigated on 12 patients with subacute or chronic prostatitis. Co-tetroxacine was given perorally, 2 x 2 tabl. daily. - Tetroxoprime-(TXP-)concentrations in prostatic fluid were 4.2 micrograms/ml and 4.5 micrograms/ml 3 and 6 hours after peroral application (days 2 and 3) respectively. Compared to the concentrations of TXP in the systemic fluid there was an increase by the factor 3 to 4.3. - The corresponding concentrations of sulfadiazine (SDZ) in prostatic fluid were 11.6 micrograms/ml and 10.0 micrograms/ml - i.e. 62-70% of the plasma concentrations.

Anti-Infective Agents↗

[Comparison of the antibacterial effects of gentamycin, tobramycin, dibekacin and amikacin in urinary germs].

We isolated 491 pathogens of urinary tract infections of our urological in-patients. Sensitivity against gentamycin, tobramycin, dibekacin and amikacin was tested in vitro. Our data were compared with the statements of the medical literature. It should be pointed out the great fraction of grampositive staphylococci. Their sensitivity rate of 40% against the tested aminoglycosides was remarkably small. Enterococci had a sensitivity rate of 70% against gentamycin, tobramycin and dibekacin. Their sensitivity rate against amikacin was only 20% as expected, because enterococci do not belong to the proper antibiotic spectrum. The four aminoglycosides are highly effective against gramnegative organisms with with no appreciable differences.

Amikacin↗

[Masked urothel carcinoma of kidney pelvis and ureter].

Behind the typical signs of a staghorn calculus of a kidney and a ureterocele with calculi in x-ray a transitional cell carcinoma of the kidney and the whole ureter was found. The nonfunction of the organ was thought to be due to pyonephrosis. Four other cases reported in the literature are discussed.

Aged↗

Ventricular response to isometric and isotonic exercise. Echocardiographic assessment.

The effects of supine isometric handgrip and graded isotonic bicycle ergometer exercise on left ventricular performance were studied echocardiographically in 20 normal subjects, aged 18 to 36. Measurements of the left ventricular minor axis diameter were taken from recordings performed at rest, during each form of exercise, and during recovery. At the completion of isometric exercise, the pressure-rate product increased significantly. There was no significant change in percentage of fractional shortening (%deltaD), while there was a small but significant fall in peak velocity of circumferential fibre shortening (peak Vcf). Isotonic exercise resulted in a significant increase in %deltaD and peak Vcf. The pressure-rate product also increased and showed a positive correlation with peak Vcf. Isotonic exercise produced a much greater stimulus to left ventricular contractility than isometric exercise and may be a useful means of detecting latent left ventricular dysfunction echocardiographically.

Adolescent↗

Percutaneous insertion of a permanent transvenous pacemaker electrode through the subclavian vein.

Insertion of transvenous permanent pacemaker leads through the subclavian vein is relatively safe and simple. This procedure was performed in 29 patients. The only serious complication was dislocation of the lead in eight patients. With this technique the endocardial lead can be positioned quite readily in the right ventricle. Use of the technique should be considered whenever the cephalic vein cannot be located readily or is too small to permit placement of an endocardial lead.

Adult↗