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Biomedical subjects

A Gerinec

Publications and source records attributed to A Gerinec.

At least 37 records · Page 2Linked to original sources

[Successful treatment of retinoblastoma].

The author analyzes the therapeutic results in 57 patients with retinoblastoma during a 30-year period in 1967-1996. The following therapeutic methods were used: enucleation, external radiotherapy, brachytherapy, chemotherapy, photocoagulation and cryopexy. By comprehensive treatment up to 84.2% survival of patients was achieved, 8.8% patients died from metastases of retinoblastoma, 5.2% from secondary tumours and 1.7% from pinealoblastomas. 72.6% affected eyes were enucleated and the remainder was cured with normal visual functions in 71.7% eyes. 48 of the surviving patients are under dispensary care and checked in collaboration by an ophthalmologist and oncologist. The author discusses problems of modern therapeutic strategy the declining frequency of enucleations and the preservation of the eyeball and useful vision.

Child↗

[Effectiveness of posterior scleroplasty in progressive myopia in children].

The authors evaluated the long-term results of posterior scleroplasty in a group 51 children (74 eyes) with progressive myopia followed up 2-4 years after surgery. Stabilization of myopia developed in the axial length of the bulbus in 78% of the children and in objective refraction in 85% patients. In 15-22% of the patients myopia progressed but only by 0.4 D per year. No serious complications were observed or after operation. The authors draw attention of ophthalmic surgeons to scleroplasty because in has a marked effect on the preventive of progressing severe myopia and thus for the long term preservation of satisfactory visual functions.

Adolescent↗

[Effectiveness of surgery in congenital esotropia].

The author analyzes cosmetic and functional results of operations of 117 patients with congenital essential esotropia. Based on a 2-6-years postoperative follow-up and different results, the author compares two sub-groups of children in the investigated group: - 72 children operated at the age of 0.5-2 years - 45 children operated at the age of 2-4 years In the first group satisfactory cosmetic results were achieved in 84.7% of the operated children, amblyopia was cured in 86.1% children, but binocular functions are present (simple ones) in 29.1% children, complete ones in 11.1%. In the second group satisfactory cosmetic results were achieved in 77.7% of the operated children, amblyopia disappeared in 71% patients and simple binocular functions were present only in 13.3% children and complete one were not achieved in any of the children. The more favourable cosmetic effect and significantly better functional effect after early surgery are reasons supporting early surgery of congenital essential esotropia.

Child, Preschool↗

[Diseases of the orbit in children].

The authors analyze their 8-years experience and therapeutic results achieved in 78 hospitalized children with different pathological conditions of the orbit. The spectrum of diseases comprised in 38% congenital anomalies, 22% tumors, 22% traumatic accidents, 13% was for orbital manifestations of systemic disease and in 5% inflammatory processes participated. The majority of patients were operated and the remainder was treated by conservative methods. The therapeutic results and other important aspects of orbital diseases are discussed.

Child↗

[Therapeutic effectiveness of local administration of corticosteroids in the treatment of orbital capillary hemangioma].

The author evaluated three years experience with the treatment of capillary haemangioma of the orbit and eyelids in nine infants. They used several therapeutic methods. However, they injected in all patients depot corticosteroids-Triamcinolone-into the tumour. Indication for treatment was a marked cosmetic defect, imminent amblyopia and progression of the haemangioma. The results of steroid treatment are very good from the cosmetic and functional aspect. Indications for treatment, results and differential diagnostic problems are discussed.

Eyelid Neoplasms↗

[Clinico-genetic aspects of retinoblastoma. II. Genetic consultation in 35 families with retinoblastoma].

The author presents a genealogical analysis of 35 families suffering from retinoblastoma and uses the results of the aetiological diagnosis to assess more accurately the ratio of heredity in the aetiology of retinoblastoma. All families received genetic consultation and the family-history was studied from the genetic and clinical aspect. The authors discuss different situations encountered during genetic consultations and outline new possibilities of screening of retinoblastoma by using discoveries of molecular genetics.

Eye Neoplasms↗

[Clinical analysis of 35 patients with retinoblastoma followed-up for 25 years].

The author presents a comprehensive analysis of a group of 35 patients with retinoblastoma followed up for 20 years at the Ophthalmological Clinic of the Faculty Hospital in Bratislava, focused on the aetiology, diagnosis, treatment and prognosis of the disease. Special emphasis is laid on the investigation of indicators which differentiate hereditary and non-hereditary retinoblastoma and on the application of these indicators for the evaluation of the clinical picture and for genetic consultations.

Adult↗

[Causes of blindness and low vision in children in Slovakia].

The authors analyze the causes of blindness in children, of Low Vision and hospital admission among pupils of the school for blind children in Levoca, a primary school for children with visual debility in Bratislava and in hospitalized children at the Ophthalmological Clinic, Faculty Hospital Bratislava. The main causes of severe visual disorders in children are in as many as 90% inborn or hereditary diseases. The latter account for 48% of the reasons for hospital admission. The authors draw attention to the increasing incidence of numerous prenatally conditioned diseases as the dominating cause of serious visual disorders in children. In this context they submit recommendations for the improvement of comprehensive care of children with defective eyesight.

Blindness↗

[Coat's syndrome in our data].

The authors submit the results of 10 years' observation and treatment of 10 children with Coats syndrome. They emphasize early diagnosis and importance of the differential diagnosis with retinoblastoma in some problematic cases. They consider photocoagulation very effective, which in eight treated children not only arrested the progression of the disease but caused also absorption of retinal exudates.

Adolescent↗

[Ectopic lens in childhood].

The authors analyze a group of 34 patients with ectopy of the lens detected in childhood and followed up for 12 years. The ectopy of the lens was not restricted to the eye but was part of numerous syndromes. The authors emphasize aetiological diagnosis, interdisciplinary collaboration and evaluation whether surgical extraction of the lens is indicated. Indication for operation is incorrigible reduction of the visual acuity below 0.3 and the imminence of complete dislocation of the lens. The long-term results of 12 operated patients are despite some complications very satisfactory from the functional aspect.

Child↗

[Terrien's corneal dystrophy].

In clinical and histomorphological case-history of a 27-year-old man the authors describe a rare corneal finding where Terrien's corneal dystrophy was confirmed. Correct evaluation of the clinical stage of the disease is considered important for the indication of microsurgical treatment. Light and electron microscopy made it possible to diagnose the dystrophic form of the disease and the clinical course confirmed the indication of surgical treatment.

Adult↗

[The Hallermann-Streiff syndrome in 2 generations].

The authors discuss a rare case, unique in our literature, of the familial incidence of Hallermann-Streiff's syndrome and the treatment of some of its complications. Special emphasis is laid on genetic analysis which provides evidence of autosomal dominant heredity with a variable expressivity of the pathological gene, and which must be applied in genetic consultations.

Adult↗

[Familial exudative Criswick-Schepens vitreoretinopathy].

The authors describe their own observation of a very rare form of vitreoretinal degeneration in a young man classified as familial exudative Criswick-Schepens vitreoretinopathy. The disease was detected in the second clinical stage on the right eye and in the third clinical stage on the left eye. The transmission of the disease is autosomal dominant with incomplete penetration. In the paper special emphasis is laid on differential diagnostic problems and the possibility of treatment of this disease.

Adult↗