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Biomedical subjects

A Guzzon

Publications and source records attributed to A Guzzon.

At least 55 records · Page 3Linked to original sources
PubMedDate not supplied

[Radiological study of complications and recurrences of esophageal carcinoma after surgery (author's transl)].

256 esophageal carcinoma patients subject to various surgical procedures were examined with a view to identifying as early as possible the complications and possible tumoral recurrences, early or late, at anastomosis level. The most caracteristic and frequent radiological features, especially of neoplastic recurrences are presented; the various morphological types are described and discussed and for the first time a radiographic classification is proposed, followed by a discussion of the criteria of differential diagnosis of these lesions, especially from postoperative perivisceritis. Correct identification and precise radiographic description of the early signs of neoplastic recurrence in the esophagogastric anastomoses make it possible to reoperate, at least in some patients.

Cardia↗
PubMedDate not supplied

Post-thoracotomy diagnostic and staging conversion rates of clinically staged I lung cancer.

The accuracy of stage I lung cancer assessment achieved by traditional clinico-diagnostic staging was retrospectively evaluated in 164 consecutive patients who underwent thoracotomy. The diagnostic conversion rate was 6.7% (1 carcinoid and 10 innocent pulmonary lesions) and occurred only in the subset of patients lacking preoperative pathologic confirmation (15%). The conversion rate to unresectable tumor extent was 8% (11/153), and local spread was the main cause of unresectability (5.5%). The staging conversion rate was 29% (43/153): the conversion rate for nodal evaluation was double that of primary tumor evaluation (24% versus 12%), but conversion to anatomically unresectable nodal diffusion occurred in only one patient (0.6%). The ability of the surgeon to convert the wrong diagnosis was scanty without extemporary biopsy, and 7 patients with innocent lesions underwent standard resection for primary cancer. Surgical staging was a precise as pathological staging in primary tumor evaluation, but was faulty in nodal evaluation (15% error in sN- and sN1-2 assessment). It is concluded that following stage I lung cancer assessment by traditional means, supplementary examinations are requested for a better sensitivity of pathological confirmation and a better refinement of local spread. Better nodal evaluation has less value until a biologic limit to surgery for anatomically resectable nodal diffusion is universally accepted.

Adult↗
PubMedDate not supplied

[Radiological study of the topography and morphology of pulmonary cancer].

This study proposes a radiological, topographical and morphological classification of primary carcinoma of the lung based on a large radiographic case-series of the National Cancer Institute of Milan checked anatomopathologically. The aim is to standardise the X-ray findings and so make for easier understanding and more rewarding cooperation among those engaged on the diagnosis and treatment of this tumor. The classification of lung cancer into central and peripheral only is felt, in the light of present knowledge, to be inadequate. It is therefore suggested that central lung cancers be divided into purely endobronchial, endoperibronchial and exobronchial, taking into account both the repercussions on ventilation and extracentral spread. For peripheral lung carcinomas more detailed morphological and topographical features are considered in order to pinpoint the tumor and its hilomediastinal spread, especially in the case of paracentral tumors. A brief reference is made to the more relevant radiodiagnostic procedures.

Bronchial Neoplasms↗
PubMedDate not supplied

[Somatic sequelae induced by radiotherapy in bone segments in adults].

The authors, on the basis of reports found in literature and of a personal series, discuss the radiological aspects, the differential diagnosis, the main factors that lead to bone sequelae, and the possible contributory causes and complications. The radiological aspects is characterized by the association of sclerotic and atrophic changes, with a prevalence of the latter in the involvement of the mandible and the cranial bones. Among the main factors there are the radiation dose and its chronological distribution. In fact, the higher the values of the nominal standard dose (NSD), the higher the incidence of such alterations and the more difficult to carry out the efficacy of their treatment. These alterations are found almost exclusively after treatment with administration, in terms of NSD, of more than 1352 rets. Among the contributory causes there are all the factors that may change the physiological condition of the bony tissue. The most common complications are fractures and septic osteitis, the last particularly frequent in the mandible. These alterations and mainly fractures may be solved even spontaneously, even if rather late, so that conservative treatments are indicated. After osteitis it is usually possible to avoid pseudoarthrosis. In cases irradiated with higher doses, osteotomy is often necessary sometime followed by poor results.

Femur↗
PubMedDate not supplied

[Radiographic semeiotics of bone metastasis in thyroid carcinoma].

It's well-known that thyroid malignant cancer often metastatizes to skeletal structures. Analysing a wide casuistry of the National Cancer Institute of Milan, we thought right not only consider most common iconographic findings of these bone metastases, but rarest too. Therefore, we studied many radiological symptoms: osteolysis and its shape; extension in the next soft tissues; absence of the periosteal reaction; some resemblances with other primitive cancer or secondary too and dysplasic focus; the changes after therapy usually give a not univocal interpretation of the pictures regarding these peculiar alterations.

Bone Neoplasms↗
PubMedDate not supplied

[Angiosarcoma of the breast: mammographic and thermographic study of 4 cases].

At Istituto Nazionale Tumori of Milan four patients with histologically proven angiosarcoma of the breast were evaluated by mammography and telethermography. This is a highly malignant rare tumor which occurs more frequently in young women. The authors outline that only 90 cases have been reported in the literature (once radiologically described in 1966) and analyze clinical and especially mammographic and thermographic signs. Radiological findings simulate those of filloiden tumors or giant fibroadenomas while thermographic patterns show a nearly generalized high hyperthermia. Therefore both methods should be associated for early diagnosis and improvement of the prognosis.

Breast Neoplasms↗