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A H Nagi

Publications and source records attributed to A H Nagi.

30 records · Page 2Linked to original sources

Primary glomerular disease with extraglomerular vascular osmiophilic deposits.

The ultrastructural changes in renal arterioles and capillaries from three cases of epimembranous nephropathy, one case of minimal change, and one case of minimal change with mild focal proliferation are presented. In addition to the usual subepithelial deposits on the glomerular capillary basement membranes in the cases of epimembranous nephropathy, osmiophilic granular deposits were observed on the outer aspect of extraglomerular vascular basement membranes. No clinical history of hypertension was obtained and there was no histological evidence of renal hypertensive vascular disease.

Adult↗

Light and electron microscopical studies of focal glomerular sclerosis.

Renal biopsy material from seven cases of the nephrotic syndrome due to focal glomerular sclerosis has been studied by light, electron, and immunofluorescent microscopy. The nature of glomerular basement membrane changes and the scar tissue was also studied. It was found that the glomerular basement membrane and mesangial matrix formed the major components of scar tissue. On the basis of a short history in some of our cases, a poor response to steroid therapy in the early stages, and the distinct morphological changes, it is suggested that focal glomerular sclerosis has an independent origin and is not a stage of minimal change lesion.

Adolescent↗