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A I Neĭmark

Publications and source records attributed to A I Neĭmark.

At least 19 recordsLinked to original sources
PubMed1994

[Changes in the hemostatic system indices of patients with chronic kidney failure under the influence of enterosorption and plasmapheresis].

A total of 83 patients with chronic renal failure (CRF) at azotemia stage (S. I. Riabov's classification) complicating pyelonephritis were treated: 19 patients received symptomatic standard therapy (group 1), 29 patients received combined therapy with enterosorption (group 2), 35 patients received combined treatment with plasmapheresis (group 3). The efficacy of the treatments was controlled by platelet tests (platelet, coagulative hemostasis, fibrinolytic plasma activity) and parameters of kallikrein-kinin system. Treatment results in group 1 are characterized as poor: insignificant improvement of uremia, DIC syndrome against unchanged inhibition of kallikrein-kinin system. Group 2 patients achieved moderate response: uremia reduced to normal azotemia values, DIC syndrome and inhibition of kallikrein-kinin system reduced. Patients of group 3 got disappeared DIC syndrome and normal kallikrein-kinin system against high azotemia.

Blood Coagulation Tests↗
PubMed1993

[The use of plasmapheresis in the combined treatment of pregnant patients with pyelonephritis].

The results of pyelonephritis treatment in 48 pregnant patients are analyzed. Twenty-three patients were administered routine antibacterial therapy, in 25 ones plasmapheresis was added to it. Immunity status of all the patients was examined. Antibiotic therapy was conducive to improvement of the patients' status, to a reduction of the renal inflammation severity, though it did not completely eliminate immunodeficiency signs. B lymphocyte and immunoglobulin levels persisted reduced. Plasmapheresis promoted a more swift elimination of clinical and laboratory signs of pyelonephritis and virtually completely liquidated immunodeficiency.

Adolescent↗
PubMed1993

[The use of plasmapheresis in treating urology patients].

The paper presents the results of plasmapheresis inclusion into a combined therapy of pyelonephritis. Out of 79 patients treated, 42 had urosepsis, 25 developed pyelonephritis in pregnancy, 12 had complicating chronic renal failure. Uroseptic patients were examined for hemostasis, the rest for immune status. There were symptoms of DIC syndrome in the former and immunity suppression in the latter. After the combined therapy with plasmapheresis, latent hypercoagulation and intoxication disappeared, uroseptic manifestations reduced. The above treatment of pregnancy pyelonephritis stopped inflammation, promoted activation of the immune system. In patients with chronic renal failure adjuvant plasmapheresis enhanced cellular and humoral immunity, neutrophil function, the number of middle-size molecules in the blood diminished. The latter improved renal function in decreasing uremia.

Adolescent↗
PubMed1990

[The use of enterosorption in the combined therapy of patients with urolithiasis complicated by chronic kidney failure].

The results of conservative treatment of 51 patients with urolithiasis complicated by chronic renal failure in the intermittent stage have been analyzed. There were two groups of patients. The first one included 36 patients receiving enterosorption in addition to routine multimodality treatment. The second group was made up of 15 patients who did not undergo enterosorption which consisted in oral application of SKH-1K coal in a dose of 10 to 15 g 3 times a day 1.5 h after meal for 10 days. The treatment efficacy was judged from the patients' general health status, central hemodynamics (cardiac index and peripheral vascular resistance), the level of azotemia, and the content of medium-sized molecules. As shown by the data obtained, the multimodality treatment coupled with enterosorption produced an appreciable improvement of the patients' health status, reduction of the signs of intoxication, while the level of medium-sized molecules and creatinine reached the control. The hypokinetic circulatory syndrome seen before the treatment disappeared. At the same time the second group patients retained the high level of azotemia, whereas the content of medium-sized molecules remained increased. Besides, they demonstrated the hypokinetic circulatory syndrome. It is thus recommended that enterosorption be applied to the treatment of patients with chronic renal failure.

Adult↗
PubMed1986

[Microcirculatory and hemostatic disorders in calculous pyelonephritis patients].

The state of microcirculation and the system of hemostasis were studied over time in 52 patients with chronic calculous pyelonephritis. Investigations were performed before operation, after 2-4 days, 5-7 days and on discharge. The patients were divided into 2 groups: with chronic pyelonephritis in the phase of active inflammation and with chronic pyelonephritis in the phase of remission. Marked disorders in the system of hemostasis characterized by hyperfibrinogenemia, thrombinemia, a decrease in the heparincofactor plasma activity, activation of platelet hemostasis, a decrease in CPa-dependent fibrinolysis were noted in the patients with calculous pyelonephritis in the phase of active inflammation. These shifts were combined with disorders in the microcirculatory system: intermittent blood flow and disseminated erythrocyte aggregation, a prolonged period of nuclide half-life in the intracutaneous depot. In the patients with calculous pyelonephritis in the remission phase shifts in the system of hemostasis were less noticeable, microcirculatory disorders were undetectable.

Adult↗
PubMed1984

[Changes in the indicators of the fibrinolytic and kallikrein-kinin systems in patients with calculous pyelonephritis].

A total of 48 patients with calculous pyelonephritis were examined before and after surgery. A study was made of the fibrinolytic system (according to the status of XIIa kallikrein-dependent fibrinolysis, lysis of the plasma clots and euglobulin lysis) and of the kallikrein-kinin system of the plasma (according to kallikrein activity, kininogen content, kininase activity, spontaneous esterase activity and prekallikrein content). The patients with calculos pyelonephritis demonstrated KKS activation and fibrinolysis reduction related to both the lowering of the activator levels and elevation of antiplasmin levels, which in turn created the risk of thrombophilia in this group of patients.

Adult↗
PubMed1980

[Changes in renal hemodynamics following experimental unilateral hydronephrotic transformation].

Electromagnetic flowmetry was used to study hemodynamics in both kidneys of 10 dogs in the presence of hydronephrotic transformation in one of the kidneys and increasing intrapelvic pressure. It was ascertained that nephrectomy of the hydronephrotic kidney affects the hemodynamics of the other one. As hydronephrotic transformation developed and intrapelvic pressure rose the blood flow in the kidney decreased while in the contralateral one dropped down. One month after the operation the blood flow in the kidney decreased 2-fold, and intrapelvic pressure increased 10-fold. Meanwhile on the contralateral side the blood flow increased by 30%. Nephrectomy of the hydrophrotic kidney resulted in further increase in the blood flow of the remaining organ.

Animals↗