PubMed Health⌕ Search

Biomedical subjects

A I Pirogov

Publications and source records attributed to A I Pirogov.

At least 19 recordsLinked to original sources
PubMed1993

[The criteria for choosing the extent of the resection of neighboring organs (structures) in lung cancer patients].

Clinical and morphological criteria for the extent of resection of the adjacent organs (structures) involved in the metastatic process were defined by analyzing 598 extensive, combined, and extensive-combined operations for giant-cell carcinoma of the lung. Morphological studies of the serial sections of resected intrathoracic structures showed that the true margins of the process extent do not always correspond to those determined on revision or palpation. It was indicated that for radical intervention, the pericardium should be resected at least at 2 cm from the visible invasion edges when a tumor is extended into it. When the process is extended into the diaphragm and chest, resection should be made at least at 2 cm of the tumor edges. In endobronchial carcinoma, the bronchus should be dissected at a distance of at least 1 cm from the tumor edges, but in peribronchial and mixed forms, it should be done at least at 2 cm. Intraoperative morphological studies are demonstrated to be of high diagnostic value in identifying the local and regional extent of lung cancer.

Adenocarcinoma↗
PubMed1992

[Effects of surgical complications on trace element metabolism in patients with cardio-esophageal and esophageal cancer].

The homeostatic features of trace elements were studied in 48 patients with cardio-esophageal and esophageal carcinoma in development of incompetence of the anastomosis sutures (17), peritonitis (19), and intestinal fistulas (12). The level of the trace elements was determined in the red cells, blood plasma, and urine by emission plasma spectrometry. With the development of surgical complications after operation on the stomach and esophagus, the metabolism of trace elements was sharply disturbed, catabolic processes prevailed and were manifested by the escape of essential trace elements from the cells and their excretion in the urine. The changes of trace elements metabolism were more profound in peritonitis and intestinal fistulas. Complex intensive therapy including artificial feeding corrected partly the metabolic disorders.

Aged↗
PubMed1991

[Disorders of trace element metabolism and their correction using artificial nutrition in patients with cancer of the esophagus in the preoperative period].

Findings of research into disorders of the micronutrient exchange in esophageal carcinoma patients are overviewed. The micronutrient level in the plasma, erythrocytes, and urea was estimated by means of emission plasma spectroscopy. Patients with esophageal carcinoma were found to have pronounced changes in the micronutrient exchange on their admission into the clinic. These changes were corrected by means of artificial nutrition, which included preparations with directed action and micronutrients. After the course of therapy a tendency towards normalization of the micronutrient exchange was observed.

Adult↗
PubMed1990

[Disorders in the sequence of regional metastasis and long-term results of the surgical treatment of complicated lung cancer].

To ascertain the frequency of disturbance of the stage character of regional metastasis in lung carcinoma complicated by disintegration or obstructive pneumonitis, and its influence on certain results of surgical treatment, the authors analysed the data on 175 patients who underwent lung resection. The stage character of regional lymphogenous metastasis was found to be disturbed in 61 (34.8%) patients, in 52 (85.2%) of them the main disease was complicated by obstructive pneumonitis. Five-year survival in the group of patients without disturbance of the stage character of metastasis was 28 +/- 4.8%, which was significantly greater than that in the group of patients with a disturbed stage character (15.5 +/- 5.2%).

Adult↗
PubMed1989

[Clinical evaluation of the small-cell and poorly differentiated forms of squamous-cell and glandular lung cancers].

The paper deals with the results of analysis of the data on 263 cases of lung cancer (small-cell--145, poorly differentiated--63 and glandular--55). Clinical manifestations and treatment procedures are discussed. The advantages offered by radical surgery used as a component of combined treatment for small-cell cancer are presented. No gain in survival was obtained by application of extended or combined surgery as compared with conservative treatment. In poorly differentiated carcinoma, radical surgery was shown to improve the end results in cases of limited expansion of tumor without involvement of the lung root or mediastinal lymph nodes.

Adenocarcinoma↗
PubMed1989

[Healing of esophagogastric anastomosis performed with the use of compression suturing equipment].

The authors' findings permit a conclusion that a compression formation of an esophagogastroanastomosis is a simpler and more reliable method than other techniques used in cases of proximal resection of the stomach. The anastomosis sutures have failed in only one of the 44 surgeries. The surgical procedure is the same as that used when the routine IIKC or CIITY equipment is employed. Unlike the anastomoses formed manually, compression anastomoses rule out one of the major drawbacks of a suture made by hand, i.e. bacterial contamination of the anastomosis area. Clamps and needles of the compression rings in anastomoses formed by means of compression apparatus AKA-2 and modified CIITY apparatus with silicone gaskets are free of the wick characteristics typical of the common suturing material, when the bacterial flora is transported into the deep-lying layers of the anastomosed organs along the thread fibers from the side of the mucosa. Resection of the proximal portion of the stomach and the lower thoracic portion of the esophagus has been carried out in 2 patients, making use of a compression anastomosis. The course of the postoperative period has been normal.

Anastomosis, Surgical↗
PubMed1988

[Prognosis of survival time in year prior to the start of radiotherapy of epidermoid carcinoma].

The results of radiation therapy of 117 patients with squamous cell lung carcinoma taking into account yearly survival were analyzed. Clinico-laboratory and roentgenological factors of prognosis were identified. The use of methods of mathematical statistics and a method of structural risk minimization made it possible to work out a decision rule permitting prognosis of yearly outcome of disease with the minimal probability of 72% even before the start of radiation therapy.

Adult↗
PubMed1985

[Multiple primary cancer in 1 lung].

The experience gained in the treatment of 29 cases of primary multiple carcinomas of one lung (synchronous--20 and metachronous--9) was analysed. Criteria for diagnosis of primary multiple neoplasms as well as choice of treatment are discussed. Surgical excision of both tumors was performed in 27 cases (synchronous--19 and metachronous--8). Surgery proved to offer considerable advantage in treatment of the lesion.

Aged↗