PubMed Health⌕ Search

Biomedical subjects

A Ia Ivleva

Publications and source records attributed to A Ia Ivleva.

49 records · Page 3Linked to original sources
PubMedDate not supplied

[The effect of isradipine on the central and cerebral hemodynamics of patients with circulatory encephalopathy and hypertension].

The new dihydropyridine calcium antagonist isradipine versus nifedipine was tested in 41 patients with essential hypertension and cerebrovascular insufficiency. The tests have shown that isradipine shows all hemodynamic effects by significantly improving cerebral blood flow and it is better tolerated than nifedipine. It is concluded that isradipine is an effective agent in the long-term management of hypertensive patients at a high risk for cerebral hypoperfusion.

Adult↗
PubMedDate not supplied

[Treatment of arterial hypertension in patients with benign prostatic hyperplasia].

Arterial hypertension (AH) is encounted in 20-30% of patients with benign prostatic hyperplasia (BPH). Alpha1-adrenoblockers have limited application in such patients and should be used as a first-line therapy only in those BPH patients who already receive them for BPH. In other cases AH is managed with thiaside diuretics, beta-adrenoblockers, ACE inhibitors or calcium antagonists. A drug of choice for correction of urination disorders in BPH hypertensive patients is alpha1A-adrenoblocker tamsulozin.

Adrenergic alpha-Antagonists↗
PubMedDate not supplied

[The action of fenigidin (nifedipine) on central hemodynamics and cerebral blood flow in hypertension].

Nifedipine is an effective agent in hypertensive emergencies as well as in the long-term management of hypertension especially for the patients with an increased risk of cerebral hypoperfusion. Nifedipine exerts its blood lowering effect by reducing total peripheral resistance including cerebrovascular resistance. Despite the marked reduction of perfusion pressure, the cerebral blood flow is maintained by nifedipine.

Aged↗
PubMedDate not supplied

[Effect of calcium-channel blockers on human thrombocyte aggregation induced by alpha-adrenoreceptor agonists].

A comparative study of the effects of calcium channel blockers nifedipine and verapamil on platelet aggregation in healthy donors induced by adrenaline. A partial agonist of alpha 2-adrenoreceptors clofelin and also clofelin in combination with the threshold concentrations of ADP inducing aggregation was performed. It was found that verapamil is a more potent inhibitor of platelet aggregation induced by adrenaline as compared with nifedipine inhibiting this process only at high concentrations. The aggregation-inducing effect of a partial agonist of alpha 2-adrenoreceptors clofelin is eliminated at low concentrations in the aggregating mixture of nifedipine than verapamil.

Adrenergic alpha-Agonists↗
PubMedDate not supplied

[Ethambutol pharmacokinetics in pulmonary tuberculosis patients].

Specific features of ethambutol pharmacokinetics were studied in 53 patients with first detected pulmonary tuberculosis. Pharmacokinetic parameters were interpreted by using an one-part model with absorption. Pharmacokinetic parameters Cmax, Me infinity were shown to be distributed according to a normal law of distribution of probabilities, Kel--according to a logarithmically normal law.

Adult↗