PubMed Health⌕ Search

Biomedical subjects

A Inoue

Publications and source records attributed to A Inoue.

At least 667 records · Page 37Linked to original sources
PubMedDate not supplied

Hepatic falciform artery: angiographic observations and significance.

BACKGROUND: The purpose of this study was to assess the angiographic incidence and appearance of the hepatic falciform artery (HFA) and discuss its clinical significance. METHODS: Hepatic angiograms of 53 patients obtained with digital subtraction angiography were prospectively evaluated with regard to incidence, anatomic features, and flow speed of the HFA. We analyzed whether the background of chronic liver disease affected the incidence of the HFA. Transcatheter arterial chemoinfusion or chemoembolization for liver tumors was performed in 33 patients. We noted the occurrence of supraumbilical skin complications. RESULTS: The HFA was observed in 13 (24.5%) of 53 patients on celiac or common hepatic angiograms. The blood flow of the HFA was slower than that of the peripheral hepatic arteries in all patients. No significant difference in the incidence of HFA between the 34 patients with chronic liver disease and the 19 patients with normal livers was found. One treated patient with an HFA and a history of gastrectomy developed a supraumbilical red skin rash. CONCLUSION: The angiographic incidence of the HFA is more common than previously reported. The delayed and persistent opacification of the HFA on hepatic angiograms caused by its slow blood flow is considered the key to its identification.

Aged↗
PubMedDate not supplied

Effect of alcohol ingestion on portal venous blood flow in healthy volunteers: comparison between the subjects with and without ALDH I isozyme.

Effect of alcohol ingestion (25 g ethanol) on portal venous blood flow was investigated in healthy subjects using an ultrasonic pulsed doppler method. It was found that; (1) portal blood flow increased by 24% at 30 minutes and returned to the basal level at 60 minutes after alcohol ingestion; (2) there was no significant difference in the effect of alcohol ingestion on portal blood flow between the subjects with and without ALDH I isozyme; (3) blood ethanol levels correlated with portal blood flow at 30 minutes after alcohol ingestion, while this correlation was not observed at 60 minutes thereafter; and (4) blood acetaldehyde levels did not correlate with portal blood flow either at 30 minutes or at 60 minutes following alcohol ingestion. In conclusion, the portal blood flow increases following alcohol ingestion which is not associated with the increase in the blood acetaldehyde level.

Acetaldehyde↗
PubMedDate not supplied

Comparison of non-tryptophan fluorophores in protein-free extract of brunescent and non-brunescent human cataract.

PURPOSE: To investigate whether any of the fluorophores in the human lens nuclei might be responsible for human brunescent cataract formation. METHODS: Human lens nuclei (non-brunescent, from 13; brunescent, from 8) were obtained after extracapsular cataract extraction in nondiabetic patients. Protein-free extract, prepared by filtrating the water-soluble fraction of each nucleus through a centrifugal ultrafilter (molecular weight < 5,000), was analytically separated by high-performance liquid chromatography. RESULTS: No significant differences between non-brunescent and brunescent nuclei were observed in the concentrations (mean +/- SD) of 3-hydroxykynurenine O-beta-glucoside (0.67 +/- 0.38 vs. 0.85 +/- 0. 62 micromol/g wet weight), 4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid O-glucoside (4.1 x 10(5) +/- 2.9 x 10(5) vs. 6.3 x 10(5) +/- 5. 0 x 10(5) area unit/g wet weight), and kynurenine (0.016 +/- 0.011 vs. 0.029 +/- 0.021 micromol/g wet weight). A novel fluorophore that has not been identified so far was significantly present more in brunescent than in non-brunescent nuclei (brunescent: 1.5 x 10(5) +/- 1.0 x 10(5) vs. non-brunescent: 2.6 x 10(3) +/- 6.3 x 10(3) area unit/g wet weight, P <.01). Digestion of the protein-free extract with beta-glucosidase eliminated the peak corresponding to the novel unidentified fluorophore. CONCLUSION: The present results imply a novel protein-unbound fluorophore, presumably a beta-glucoside, might possibly be involved in brunescent cataract formation.

Aged↗
PubMedDate not supplied

Results of surgical treatment of muscular torticollis for patients greater than 6 years of age.

From 1983-1989, 37 patients with muscular torticollis were treated surgically by partial resection of the distal portion of the sternocleidomastoid muscle. Of these, 19 patients who at surgery were greater than 6 years of age (average 11 years 2 months) were followed for greater than 1 year (average 2 years 2 months). Although both function and cosmesis were improved in all cases, scoliosis was a residual deformity in some cases, especially in girls.

Adolescent↗
PubMedDate not supplied

Quantitation of c-erbB-2 gene amplification in breast cancer tissue by competitive PCR.

Controversy exists regarding the relationship of the degree of c-erbB-2 amplification to other prognostic factors in breast cancer. To determine the degree of amplification of c-erbB-2 exactly, a sensitive and quantitative method is required. We have developed a competitive PCR method to quantitatively determine the amplification of the c-erbB-2 oncogene. Using this method, we evaluated DNA from 27 breast cancer tissue specimens and DNA from peripheral blood leukocytes from a normal individual. Regarding the relationship between the degree of c-erbB-2 amplification and clinicopathological factors, we found a greater degree of amplification of the c-erbB-2 oncogene in estrogen receptor- negative or progesterone receptor-negative specimens than in positive ones and in lymph node metastasis-positive specimens than in negative specimens, in stages II, III, and IV of disease compared with stage I disease, and in samples with positive lymphatic vessel invasion than with no lymphatic vessel invasion. Generally, these factors were seen in the group of patients who had a bad prognosis. By univariate analysis and multivariate analysis, reverse correlation was observed between amplification of c-erbB-2 and overall survival. Regarding disease-free survival, these relationships were observed only with univariate analysis in our group of patients.

Adult↗
PubMedDate not supplied

Garden path repair: diagnosis and triage.

Meng and Bader (2000b) have shown that for garden-path repair in German, case is a more effective cue than number. They argue that sensitivity to the nature of the cue supports a diagnosis model of garden path repair such as we have proposed. However, in making this argument Meng and Bader introduced a new notion of diagnosis. Retaining the original "basic" diagnosis system, they added a new function that we call triage. Triage determines the probable revisability of a structure, in order to decide whether to make the effort of trying to reanalyze it. To determine whether triage is a feature of human parsing, its scope must be established. We compare four hypotheses about how much work triage could do. A powerful triage component would succeed where the human parser fails. Limited local triage does no work if symptom effectiveness varies within a language. An intermediate hypothesis discriminates better between easy and difficult revisions. However, this variant of triage with the strongest claim to psychological reality is the most difficult to distinguish from no triage at all, since it shares important properties with basic diagnosis. We identify some empirical predictions that differentiate diagnosis with triage from simple basic diagnosis. What little evidence there is at present suggests that the human sentence parser has no triage capability.

Cues↗
PubMedDate not supplied

Peripheral neuropathy associated with Sjögren's syndrome: pathologic and immunologic study of two patients.

Two cases of Sjögren's syndrome accompanied by peripheral neuropathy are reported. The level of anti-endothelial cell antibody was increased in both patients. Immunofluorescent deposits of immunoglobulin and C3 component were detected in the vasa nervorum of both cases. The pathological findings showed damage to the endothelial cells in the same vessels. The findings suggest that injury from immune complex and anti-endothelial cell antibody may be the immunological factor in the induction of peripheral neuropathy.

Adult↗