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Biomedical subjects

A J Veliath

Publications and source records attributed to A J Veliath.

52 records · Page 3Linked to original sources

Primary lymphosarcoma of the lung with unusual features.

Two unusual cases of primary lymphocytic lymphosarcoma of the lung are presented. The first patient is a 5-year-old girl who showed a massive involvement of the entire right lung by tumour. She was treated by radiotherapy followed by cyclophosphamide and was alive and well one year later. The second patient was an adult man who presented clinically with a tumour of the chest wall. Necropsy revealed an extensive direct spread of pulmonary lymphosarcoma with infiltration of the chest wall but without metastatic dissemination or lymph node involvement. Neither primary lymphocytic lymphosarcoma of the lung in a girl of 5 years nor presentation of such a tumour as a chest wall mass in an adult seems to have been described previously.

Adult↗

Cutaneous phycomycosis (mucormycosis) with fatal pulmonary dissemination.

Phycomycosis of the skin manifested as a spontaneous solitary ulcer of the leg in a patient with uremia. The infection later spread to the lungs and produced fatal pulmonary infarction. Histopathologic study of the lesions revealed broad nonseptate fungal hyphae that had invaded vascular channels, with areas of necrosis and acute inflammation. Primary cutaneous phycomycosis is rare. In the studied cases, dissemination of infection did not occur. The unusual feature of fatal pulmonary dissemination of primary cutaneous phycomycosis as observed in our patient has not been described in the leterature.

Adult↗

Ovarian giant cell tumor with cystadenocarcinoma.

A 25-year-old woman had a malignant ovarian tumor with two distinct tumor patterns: pseudomucinous cystadenocarcinoma and malignant giant cell tumor of bone. One area of the tumor had a lining of tall columnar epithelium with abundant mucin production; however, another area of the same tumor had a number of large multinucleated giant cells that resembled osteoclasts, intermingled with mononuclear stromal cells. There was no blending of the two tumor patterns. Mitoses were frequent in both areas. A probable histogenesis of the tumor from a malignant teratoma is suggested.

Adult↗

Tumoral calcinosis.

Tumoral calcinosis is an interesting clinical entity. It is not uncommon in certain countries. We report our experience with 22 patients with this condition seen over a 7-year period and review in detail the modalities of clinical presentation, theories of etiogenesis, histological appearances, and treatment modalities.

Adult↗

Perinatal autopsy--a seven-year study.

A retrospective analysis of autopsies conducted on perinatal deaths during 7 years period (Oct 1983 to Sept 1990) was done. There were 650 neonatal deaths and 944 still births during the study period. Autopsy rates among neonates and still births were 33% and 4.9% respectively. There ware significant findings in 97.2% of neonatal deaths and in all still births. Pulmonary lesions followed by congenital malformations were the major pathological findings. Infection was observed among smaller number of babies compared to other Indian studies. Autopsy revealed many internal congenital malformations which were not diagnosed clinically. Autopsy changed or added to clinical diagnosis in 59.5% of cases. Perinatal autopsy is highly productive in our set up.

Autopsy↗

Xeroderma pigmentosum: resurfacing versus dermabrasion.

Three patients of Xeroderma Pigmentosum (XP) have been managed for recurrent tumours. Improvement in pigment pattern was observed at both the donor as well as the recipient sites. An attempt has been made to prevent further occurrence of tumours over the exposed parts of the body by resurfacing and also by dermabrasion. A comparative study of the two procedures is being carried out and the preliminary results are discussed. Deep dermabrasion appears to be preferable as a prophylactic procedure.

Adult↗