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Biomedical subjects

A Jörgensen

Publications and source records attributed to A Jörgensen.

4 recordsLinked to original sources
PubMed1991

Creating changes in the corporate culture: case study.

The case study describes the experience of an OHN in starting a process of reorganization in a company. The concept was a "safety round" with a questionnaire created by safety officers and the OHS who also were responsible for getting the information to all employees, planning, carrying through, and evaluating the project. Last but not least, they should be aware of the consequences such a project could start. The results of the project were: a) the reorganization of the corporation should be evaluated for further development; b) the instruction plan should be reviewed with new employees, with better follow up and continuity; c) a survey should be done of future educational needs of the staff. Job rotation should be a priority; and d) a programmed schedule should be set for meetings in the line of production. The role of the OHN in the project was to support the changes and push for the follow up work after 1 year.

Humans↗
PubMed1990

Inoculation of barrier-born pigs with Helicobacter pylori: a useful animal model for gastritis type B.

At the age of 8 weeks, 15 barrier-born pigs, specific pathogen free, were inoculated intragastrically with suspensions of 10(7) to 10(10) CFU of Helicobacter pylori after pretreatment with omeprazole. The pigs were observed for up to 12 weeks, endoscopic biopsy specimens were taken, and serum samples were drawn. H. pylori was identified by routine culturing and by staining with an H. pylori-specific monoclonal antibody on cryostat sections of gastric biopsy specimens. In 11 of 15 inoculated pigs, H. pylori was detected throughout the observation period. In these infected pigs, there was an antibody response to H. pylori, as determined in serum by an enzyme immunoassay. Furthermore, the development of superficial, focal gastritis with infiltrates of mononuclear class II antigen-expressing lymphocytes was observed immunohistologically. H. pylori was never detected and an antibody response to H. pylori was not observed in two control pigs. The development of gastritis and the systemic antibody response to H. pylori support the usefulness of this animal model for studies of H. pylori-related human diseases.

Animals↗
PubMed1975

Penumoencephalographic findings in parkinsonism.

Pneumoencephalograms of 19 patients with unilateral parkinsonism, and of 26 patients with symptoms of generalized parkinsonism were studied. Cortical atrophy was found in 46.7% (21), while central (ventricular) atrophy occurred in 77.8% (35) of the patients. The percentage of patients with cortical atrophy, or with enlargement of ventricular body span (VBS) and septum-caudate distance (S-C), was smaller in the hemiparkinsonism group. No substantial correlation was found between enlargement of frontal horn width (FH), S-C and third ventricle width (3V), and the duration of illness. Likewise, no noteworthy correlation could be seen between the degree of central atrophy and the severity of the clinical symptoms. The FH/S-C ratio of the group of unilateral parkinsonism patients was higher than in the generalized parkinsonism group. The FH/S-C ratios in parkinsonism and in Huntington chorea patients varied. A ratio of greater than 1.40 was found in 73.3% of the patients with parkinsonism, and in an earlier study, it was found that 96.4% of the patients with Huntington chorea had a ratio less than 1.40. It is suggested that a FH/S-C ratio less than or equal to 1.40 is compatible with the diagnosis of Huntington chorea, although 26.7% (12) patients with parkinsonism have a ratio less than or equal to 1.40.

Adult↗