PubMed Health⌕ Search

Biomedical subjects

A K Gruzdev

Publications and source records attributed to A K Gruzdev.

At least 19 recordsLinked to original sources
PubMed2004

[The use of intraaortic balloon counterpulsation in patients with acute myocardial infarction].

Intraaortic balloon counterpulsation was implemented in 11 patients with acute myocardial infarction and 1 patient with unstable angina. All patients had severe multivessel coronary artery disease. In 9 patients counterpulsation was used in conjunction with percutaneous transluminal coronary angioplasty, in 3 - with thrombolytic therapy. During hospitalization 2 patients died of progressing heart failure, while significant improvement of hemodynamic parameters occurred in other patients. Thus intraaortic balloon counterpulsation used in combination with angioplasty and thrombolytic therapy is an easily accessible highly effective method of treatment of cardiogenic shock in patients with acute myocardial infarction

Angioplasty, Balloon, Coronary↗
PubMed2002

[Long term use of a non-selective beta-blocker with vasodilating properties carvedilol in patients with severe heart failure].

Results of drug treatment of 51 patients (41 men, 10 women) aged 35-86 years (mean age 62 years) included into COPERNICUS trial are presented. All patients had compensated NYHA class IV chronic heart failure and left ventricular ejection fraction less than 25%. For at least 2 months the patients received therapy with diuretics and angiotensin converting enzyme inhibitors (84%) or angiotensin receptor blockers (16%) and then were randomized to either carvedilol or placebo. Average duration of follow-up was 17 months. Carvedilol was well tolerated both during dose titration and during maintenance therapy. Addition of carvedilol to standard therapy of patients with severe heart failure was associated with increase of average ejection fraction from 21.7 to 30.3%. Rates of cardiovascular and sudden deaths, risk of hospitalization among carvedilol treated patients were 25, 33 and 57% less than among patients subjected only to standard therapy.

Adrenergic alpha-Antagonists↗
PubMed1992

[Heart failure in acute myocardial infarction: comparing infusions of nifedipine and nitroglycerin].

The impact of intravenous infusion of nifedipine and nitroglycerin on invasive central hemodynamic parameters and microcirculation was compared in 94 patients with acute myocardial infarction complicated by heart failure. The artery dilating effects of nifedipine were associated with baseline peripheral vascular tone, so the comparison was made separately in the groups with and without vasoconstriction. Nifedipine seems to be beneficial in the management of heart failure due to acute myocardial infarction in patients with systemic vasoconstriction. In patients with severe pulmonary congestion and normal left ventricular afterload, the intravenous vasodilators are preferable.

Adult↗
PubMed1992

[Effect of acetylsalicylic acid on the indicators of thrombocytic hemostasis in patients with myocardial infarction].

The examination of 50 patients with acute myocardial infarction indicated that enhanced platelet functional activity was a prognostically unfavourable sign and associated with a higher risk for myocardial infarction complications. The application of aspirin, 250 mg daily, in patients with high platelet functional activity in the acute period of the disease failed to produce a beneficial antiaggregatory effect.

Administration, Oral↗
PubMed1991

[Use of intravenous nifedipine in the treatment of cardiac insufficiency in the acute period of myocardial infarction].

The efficacy of intravenous nifedipine was examined in 42 patients with acute myocardial infarction complicated by congestive heart failure. In patients with a higher systemic arteriolar tone, its normalization caused an increase in cardiac output and tissue oxygen supply with a concomitant decrease in pressures in the lesser circulation and the right heart. In contrast, a cardiodepressive effect of the agent was shown in more than a half of the patients with para-normal values of peripheral vascular resistance. The latter is one of the determinants in selecting patients with acute heart failure to be treated with nifedipine.

Aged↗
PubMed1990

[Disorders of hemodynamics and pulmonary gas exchange in the acute period of myocardial infarct].

In 40 patients with massive myocardial infarction, the central hemodynamics was examined by probing the right-sided chambers of the heart and the pulmonary artery. The cardiac output was measured by thermodilution. The gas exchange (respiratory minute volume, capnography, gas analysis of arterial and mixed venous blood) was explored. Arterial hypoxemia was found to be associated with increased intrapulmonary blood shunting in patients with acute myocardial infarction complicated by congestive heart failure. Deterioration of arterial hypoxemia was promoted by a combination of increased overall pulmonary shunting and decreased residual venous oxygenation. Abnormalities in the ventilation-perfusion relations are of great importance.

Aged↗
PubMed1988

[The role of abnormally located chordae in the origin of accidental heart murmurs in children].

A study of 55 children with accidental systolic and diastolic heart murmurs demonstrated that abnormal chorda position (ACP), detected at echocardiography in various heart cavities, was the principal contributing factor. The relationship between the intensity and other parameters of systolic murmurs and abnormal chorda topography is discussed. Abnormal position of the chordae was not associated with any deviations from basic morphometric characteristics of the heart and should therefore be regarded as a normal variant.

Adolescent↗
PubMed1988

[Use of automation potential in intensive care units of a multi-profile hospital].

An example of an automated information system of a large general hospital has shown that using a sufficiently informative clinical data base (with a minimal set of parameters) on patients in intensive care departments, it is possible to provide information inquiries of diagnostic units and hospital administration without distracting staff-members on duty to report on the patients' state. The use of an automated bed turnover management system made it possible to reduce the time of patients' admission to hospital, to improve the planning of hospitalization and hospital transfers, to raise the efficacy of bed turnover, and to reduce unproductive labor of the hospital staff.

Forms and Records Control↗
PubMed1987

[Clinical observation of the repeated use of isolated ultrafiltration in treating chronic circulatory insufficiency].

Repeated courses of isolated ultrafiltration performed 4 times within 19 mos. in patients with chronic heart failure against a background of drug therapy resulted in remissions. The authors assessed positively the clinical effect of each course of procedures supported by the results of echocardiographic investigations. No significant changes in laboratory findings were noted.

Chronic Disease↗
PubMed1985

[Diagnosis of infectious endocarditis and the assessment of the effectiveness of its treatment].

The results of investigation and treatment of 58 patients with infectious endocarditis are presented. Changed clinical pattern of the disease, its increasing incidence among older people and the emergence of its "immunologic" variety with signs of myocarditis, vasculitis and, less commonly, glomerulonephritis have been noted over recent years. The disease has become polyetiologic. Methods of treatment for infectious endocarditis are discussed with reference to the etiology and clinical pattern of the disease. Indications for surgical treatment are outlined.

Adolescent↗
PubMed1985

[Isolated ultrafiltration in treating chronic heart failure].

Twenty-five patients with chronic heart failure resistant to drug therapy were subjected to isolated ultrafiltration (IUF) as part of the complex of therapeutic measures. Altogether 76 IUF sessions were made. The results of the use of IUF were controlled by the clinical observation, laboratory studies and ultrasonic exploration of the internal organs. It has been shown that IUF should be included into the complex of therapeutic measures for chronic heart failure.

Adult↗
PubMed1985

[Comparative clinico-instrumental characteristics of different morphological variants of hypertrophic cardiomyopathy].

Six morphologic variants of hypertrophic cardiomyopathy (HCMP) have been identified on the basis of the echocardiographically-documented extent and localization of left-ventricular hypertrophy in 34 patients with HCMP. More than half of the patients had no complaints. The more characteristic echocardiographic features of the disease included a considerable thickening of one or more departments within the left ventricle, the size of its cavity being diminished. In most cases, HCMP was associated with considerably enlarged R waves on the electrocardiograms from 35 precordial leads that were usually combined with ST segment depression and T wave inversion. The latter two features often provided grounds for a hyperdiagnosis of coronary heart disease (CHD). What distinguishes HCMP from CHD is the discrepancy between marked and persistent pathologic electrocardiographic changes and a relatively uneventful clinical picture of the disease. The comparison of echocardiographic and ECG charting data allows a more detailed assessment of the kind of left-ventricular hypertrophy in HCMP patients, and can be used in the differential diagnosis of HCMP vs. CHD.

Adult↗