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Biomedical subjects

A M Calafiore

Publications and source records attributed to A M Calafiore.

At least 109 records · Page 6Linked to original sources
PubMed1977

[The surgical treatment of discrete subaortic stenosis (author's transl)].

The AA. examine their experience concerning 23 patients operated on for a discrete subaortic stenosis since 1969. Immediate results are satisfactory, even if there have been postoperative complications in 26% of the patients. Late results are less satisfactory, above all because of the progression of aortic insufficiency far from the operation. Date of literature are nor allowing valuable indications about the natural history of the patient after surgical treatment, because of the scarcity of postoperative hemodynamic controls and, especially, of serial examinations. The AA. believe, on the ground of considered data and personal experience, that it is prudent, awaiting for further critical evaluation of late results, to limit surgical indications, in asymptomatic patients, to cases with left ventricular-aortic gradient superior to 70 mmHg.

Adolescent↗
PubMed1975

[Classification of congenital aortic stenosis].

Recent epidemiological data relating congenital stenosis of the aorta are cited. An anatomical criterion is used in the formation of three classification groups, each containing a number of different types. There are no clear-cut clinical pictures corresponding to these anatomical varieties, however, so that differential diagnosis is dependent on the haemodynamic and contrastographic data. There are, on the other hand, clinical signs that serve as pointers to the site of the stenosis.

Adolescent↗
PubMed1975

[Results of surgical therapy of the partial form of persistent common atrioventricular canal (author's transl)].

20 patients with partial form of persistent common atrioventricular canal underwent surgery at the Centro di Cardiochirurgia "A. Blalock", University of Turin, between 1969 and 1974. In each case the treatment of lesions took place in the following order: the repair or replacement (one case) of the mitral valve; the closing with a patch of the atrial septal defect; the repair, in one case, of the tricuspid. The most frequent post-operative complications were arrhythmias, which in two cases consisted of a total atrioventricular block. Only one patient died postoperatively for an acute pulmonary oedema following an imperfect mitral valve correction. Six months after surgery, another patient died from bacterial endocarditis. Thirteen of the eighteen surviving patients showed excellent results at the clinical and/or hemodynamic check; two had fair results and three had poor results. In two cases, mitral insufficiency was hemodynamically aggravated, whilst in another five it disappeared. In eight, a slight apex systolic murmor 1-2/6 persisted, which was not correlated with any radiological or electrocardiographical sign of mitral insufficiency (and for three of these, not even a hemodynamic one). The authors consider that the most difficult problem in surgical therapy for these malformations is still the treatment of mitral lesions.

Adolescent↗
PubMedDate not supplied

Intermittent antegrade warm blood cardioplegia in aortic valve replacement.

BACKGROUND: Intermittent antegrade warm blood cardioplegia (IAWBC) is a well established technique of myocardial protection for coronary artery surgery, with metabolic and experimental basis. METHODS: To evaluate its effectiveness in aortic valve replacement (AVR), we compared 171 consecutive patients who underwent first AVR using IAWBC (group A) with the last 100 consecutive patients who underwent first AVR using intermittent antegrade cold blood cardioplegia (IACBC) (group B). The endpoints considered were myocardial protection related (recovery of spontaneous rhythm, need for mechanical support, incidence of low-output syndrome, perioperative Q wave myocardial infarct, CK-MB levels, ventricular arryhthmias and lidocaine infusion requirement, cardiac-related deaths, and deaths any cause) and temperature perfusion related (bleeding, awaking time, time to extubation, and cerebrovascular accidents). RESULTS: Mortality was similar in both groups, but no patient in group A died for cardiac-related cause (0 vs 4, p < 0.01). More patients in group A recovered a spontaneous rhythm (144 vs 47, p < 0.0001). Incidence of low-output syndrome was higher in group B (16 vs 3, p < 0.0005), as well as ventricular arryhthmias incidence and need for lidocaine infusion (respectively 15 vs 2, p < 0.0001, and 10 vs 1, p < 0.0005). Awaking time was shorter in warm patients (2.5 +/- 2.5 hours vs 4.4 +/- 3.7 hours, p < 0.0005), as the extubation time (9.4 +/- 7.7 hours vs 13.5 +/- 11.7 hours, p < 0.0005) and bleeding (803 +/- 714 mL/24 hours vs 1051 +/- 1375 mL/24 hours, p < 0.05). As a consequence, the intensive care unit and the postoperative hospital stays were shorter in group A (32 +/- 27 hours vs 48 +/- 20 hours, p < 0.0005, and 7.2 +/- 3.1 days vs 11.3 +/- 5.4 days, p < 0.0001, respectively). CONCLUSIONS: IAWBC provides lower cardiac-related mortality and morbidity in patients who undergo AVR in comparison with IACBC.

Aged↗