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Biomedical subjects

A M Rossignol

Publications and source records attributed to A M Rossignol.

At least 37 records · Page 2Linked to original sources
PubMed1996

Lifestyle and risk of premature sexual activity in a high school population of Seventh-Day Adventists: Valuegenesis 1989.

In the past 20 years, sexually transmitted diseases (STDs), including AIDS, and the physical, psychological, and economic difficulties associated with unwanted pregnancy have increased steadily among American adolescents. The objective of this study was to evaluate Adventist lifestyle as a modification of popular American culture which reduces the risk of early sexual activity in adolescents and thus also reduces the risk for both STDs and teen pregnancy. The study was based on 8,321 respondents to a questionnaire concerning specific behaviors, beliefs, and attitudes among Seventh-Day Adventist youth attending 58 high schools in North American. Analysis of the data demonstrated that a wide variety of behaviors were associated with premature sexual activity, including previously reported high-risk behaviors such as drug or alcohol use. In addition, several behaviors that are discouraged within Adventist culture, such as going to a movie theater or participating in competitive sports, also were associated with early sexual activity. It is hypothesized that these latter behaviors may predict the emergence of other high-risk behaviors, such as early sexual activity, in both Adventist and popular cultures, and thus may be "transition-marking behaviors" as described by Jessor and Jessor (1975).

Adolescent↗
PubMed1996

[Cardiac output evaluation during exercise in children treated with atrial surgery for transposition of great vessels].

The long-term physiopathological consequences of atrial surgery (Senning or Mustard procedures) for transposition of the great vessels with respect to exercise capacity are not well known. We measured the cardiac index by the technique of CO2 rebreathing at two submaximal levels of exercise corresponding to a stable oxygen consumption of 20 (E20) and 30 (E30) ml/min/kg in 7 patients successfully operated for transposition of the great vessels and in 7 control children paired for age, gender and body surface area. Despite an identical chronotropic response to exercise in the two groups, the increase in cardiac index was not as great in the children operated for transposition (from 6.86 +/- 0.51 to 7.71 +/- 0.78 l/min/m2) as in the control population (from 7.71 +/- 0.78 to 10.2 +/- 0.51 l/min/m2; p < 0.02). The stroke volume index was therefore significantly lower in the transposition group at both levels of exercise (52 +/- 3.2 vs 63 +/- 4.1 ml/m2; p < 0.04 at E20; and 46.4 +/- 4.3 vs 66 +/- 5.1 ml/m2 at E30). The main cause of this reduction of the stroke volume index is probably a lack of adaptation of right ventricular systolic function on exercise but it is not possible to exclude diastolic dysfunction due to reduce compliance secondary to the intraatrial patch. The conditions of preload are in fact instrumental in increasing stroke volume index at submaximal exercise levels.

Adaptation, Physiological↗
PubMed1995

Are ethical topics in epidemiology included in the graduate epidemiology curricula?

The objective of this study was to evaluate, via a mail questionnaire, the extent to which topics in epidemiology are included in the graduate epidemiology curricula in departments of epidemiology within the 24 US schools of public health. Responses from 101 faculty (79% of faculty queried) indicated that 86% believed that education concerning ethical issues in epidemiologic research should be included in the curriculum. Topics included most frequently are ethical issues concerning protection of human subjects, clinical trials, screening programs, and use/abuse of data. The most common mode of presenting these topics is through one-on-one mentoring or through seminars.

Curriculum↗
PubMed1994

Maternal deaths among women with pregnancies outside of family planning in Sichuan, China.

To assess the impact of family planning status on maternal mortality, we analyzed data gathered in a community-based, maternal mortality surveillance study conducted by the Sichuan Health Department in the People's Republic of China during 1989-1991. The overall maternal mortality ratio, which included only deaths of pregnant women within family planning guidelines ("planned" pregnancies), was 78.9 per 100,000 livebirths. When the deaths of pregnant women outside of family planning ("unplanned" pregnancies) were included, the maternal mortality ratio doubled to 135.6 per 100,000 livebirths. The leading causes of death for women with "planned" and "unplanned" pregnancies were the same: hemorrhage, postpartum infection, pregnancy-induced hypertension, cardiac diseases, and pulmonary diseases. As among women with "planned" pregnancies, about 40% of maternal deaths among women with "unplanned" pregnancies occurred at home, and 20% occurred en route to a hospital. After controlling for the confounding effects of gravidity and education, the odds ratio of maternal death associated with "unplanned" pregnancy status was 2.6 [95% confidence interval (CI) = 2.0-3.7], which declined to 2.0 (95% CI = 1.4-2.9) with additional control for the effect of prenatal care visits. Our study indicates that women with "unplanned" pregnancies have a higher risk of maternal death, which is only partially attributed to less prenatal care.

Adolescent↗
PubMed1994

Malaria in central Haiti: a hospital-based retrospective study, 1982-1986 and 1988-1991.

A retrospective study conducted at central Haiti's Albert Schweitzer Hospital in the June 1991-January 1992 period sought to assess the numbers of malaria cases seen at the hospital in 1982-1991, the distribution of cases by age and sex in 1988-1991, and the validity of official reports indicating an overall decline in malaria cases. Review of the hospital's laboratory records (1982-1986, 1988-1991), patient medical records (1989-1991), and patient discharge summary cards (1989-1991) revealed a total of 5,251 malaria cases identified through examination of approximately 65,000 blood smears. The largest numbers of cases were diagnosed in 1982 (1,150) and 1988 (980); the smallest numbers in 1990 (120) and 1991 (317). Peak case incidences occurred yearly in the November-January period, a few months after the rainy season. Of the 838 cases found in the 1989-1991 period, 53% occurred in females and 47% in males. Relatively high numbers of cases (averaging 41.1 cases per year of age) were found among children 0-6 years old, with the largest number of cases in any 1-year age group (54 cases) occurring among children 1 year old. (In general, the numbers of cases declined with increasing age.) Eight cases among hospital in-patients ended in malaria-related death, five of these deaths occurring among children 0-6 years old and six involving cerebral malaria (a common complication of P. falciparum infection). Overall, the results of this study support official reports showing a general decline in the number of malaria cases in this region of Haiti between 1982 and 1991.

Adolescent↗
PubMed1993

Evidence against multiple premenstrual syndromes: results of a multivariate profile analysis of premenstrual symptomatology.

The topic of a single vs multiple premenstrual syndromes has generated much discussion. In this study, multivariate profile analysis was used to determine whether or not physical and affective symptoms associated with the premenstrual syndrome (PMS) could be explained as the manifestation of one underlying pathophysiologic process. The premenstrual symptom profiles of 820 undergraduate students and 485 graduate students were evaluated. It was not possible to reject the null hypothesis of parallel profiles in most comparisons, suggesting that variability in the severity of premenstrual symptoms may be the result of individual differences in the expression of one underlying pathophysiologic process.

Adolescent↗
PubMed1993

Effects of passive smoking on respiratory illness from birth to age eighteen months, in Shanghai, People's Republic of China.

The objective of this study was to evaluate the effects of exposure to nonmaternal, passive household cigarette smoke on the incidence of respiratory illness (bronchitis and pneumonia) among children from birth through age 18 months in the Lu-Wan District, Shanghai City, People's Republic of China. A secondary objective was to evaluate the effects of other environmental factors, such as the fuel used for cooking and whether the child was breast fed, on the incidence of respiratory illness. The total daily cigarette consumption of family members was used to estimate exposure to passive smoke. The relative risks of exposure to passive cigarette smoke on the incidence of respiratory illness were 1.3, 1.7, and 2.0 for children living in households with members who smoked 1 to 9, 10 to 19, and 20 to 39 cigarettes per day, respectively, compared with the risks for children living in nonsmoking households (p for trend = 0.0002). These effects did not change materially when potential confounding factors were controlled. Children who were not fed human milk had a 1.8-fold increased risk of respiratory disease at each level of exposure to passive cigarette smoke evaluated, in comparison with children who were fed human milk for at least 1 month.

Breast Feeding↗
PubMed1993

Complications of BCG vaccinations in rural Haiti.

This study investigated an outbreak of axillary lymphadenitis and abscesses after Bacillus Calmette-Guérin vaccination among rural Haitian children treated at the Hospital Albert Schweitzer from January 1986 through March 1991. Seventy-seven cases of vaccine-related complications were identified, all among children immunized before the age of 1 year. The proportions of children with complications were 0.017% for 1986 through 1989, 0.91% for 1990, and 2.2% for January through March 1991.

Abscess↗
PubMed1992

[Measurement by Doppler echocardiography of the ratio of pulmonary/systemic flow rates in atrial septal defects. Apropos of 15 cases].

Fifteen patients with an ostium secundum type atrial septal defect, aged between 5 and 68 (mean = 31) underwent Doppler-echocardiographic evaluation of the ratio of pulmonary and systemic flow rates. Systemic flow was evaluated at the aortic orifice, as well as at the mitral ring and at the extremities of the mitral cusps, based upon the measurement of valve diameters by 2D or TM echocardiography, pulsed Doppler velocity curve and hear rate. Pulmonary flow was measured by the same technique at the site of insertion of the pulmonary cusps. The values obtained were compared with cardiac catheterisation findings, the reference method being an oxymetric measurement of the shunt ratio. Feasibility of the Doppler investigation was 100 per cent. Correlation between the two techniques was r = 0.85 when the Doppler measurement was at the aorta, r = 0.81 for the mitral ring and r = 0.71 at the extremity of the mitral cusps. Doppler-echocardiography thus appears to be a reliable and reproducible method for the evaluation of left-right shunts, confirming data from the literature.

Adolescent↗
PubMed1991

Do women with premenstrual symptoms self-medicate with caffeine?

Recent investigations have suggested that caffeine consumption is related to the occurrence and severity of premenstrual symptoms. Phillis has proposed that not only the total amount of caffeine consumed but also the pattern of consumption over the menstrual cycle may be important. This study explored whether women who experience moderate or severe premenstrual symptoms differ from other women in their pattern of caffeine intake throughout the menstrual cycle. Analysis of data for 96 complete menstrual cycles from 47 women demonstrated that caffeine intake during the menstrual cycle differed between women who experience moderate or severe premenstrual symptoms and other women. Furthermore, the monthly pattern of caffeine consumption for women with moderate or severe premenstrual symptoms, but not for other women, differed substantially from Phillis's proposed beneficial pattern. Women with premenstrual symptoms may self-mediate with caffeine in response to premenstrual symptoms, thereby exacerbating their symptoms.

Adolescent↗
PubMed1991

[Transient myocardial ischemia and isolated congenital mitral valve prolapse in an infant].

The investigation of a cardiac murmur in a 9 month old infant led to the clinical, echo and angiographic diagnosis of congenital mitral regurgitation due to isolated mitral valve prolapse, whereas the electrocardiogram showed signs of inferior myocardial ischaemia which regressed in a week. The valvular dysfunction of mitral valve prolapse has been held responsible for coronary spasm ischaemia and infarction in adults. This complication has not been previously reported to our knowledge in infancy.

Angiocardiography↗
PubMed1991

Prevalence and severity of the premenstrual syndrome. Effects of foods and beverages that are sweet or high in sugar content.

The objective of this study was to evaluate whether certain foods and beverages that are high in sugar content or taste sweet are related to the prevalence and severity of the premenstrual syndrome. Specifically, we sought to evaluate whether consumption of "junk foods", chocolate, caffeine-free cola, fruit juices or alcoholic beverages might exert an effect on the premenstrual syndrome apart from any effects of daily consumption of beverages that are high in caffeine (caffeine-containing coffee, tea and colas). The study was based on 853 responses to a questionnaire probing menstrual and premenstrual health and certain daily dietary practices; it was mailed to female university students in Oregon. An analysis of the data revealed that the consumption of chocolate, but not of other junk foods, was related to the prevalence of the premenstrual syndrome among women with more severe premenstrual symptoms. Likewise, the consumption of alcoholic beverages (all alcoholic beverages and beer only) was related to the prevalence of the premenstrual syndrome among women with more severe symptoms, as were both fruit juice and caffeine-free soda. None of the associations was substantially altered when the daily consumption of beverages high in caffeine content was controlled for. Taken together, these data suggest that the consumption of foods and beverages that are high in sugar content or taste sweet is associated with prevalence of the premenstrual syndrome.

Adolescent↗
PubMed1990

Socioeconomic factors and the incidence of hospitalized burn injuries in New England counties, USA.

This study demonstrates that readily available socioeconomic data routinely collected by the US Census can be used to estimate the incidence of burn injuries within the 66 counties of the populous six-state New England region of the USA. The burn data were collected during the National Burn Demonstration Project and included New England residents admitted for hospital care of burns sustained between 1 July 1978 and 30 June 1979. Linear regression analysis revealed strong associations between calculated burn rates and a number of socioeconomic variables. Associations with five such variables are described, including per capita income, percentage of persons below poverty level, percentage of residences built prior to 1940, percentage of adults with 16 years or more of education, and percentage of persons moving since 1975 with previous residence in the same county. Estimates of burn incidence for counties, together with a previously reported study at the level of census tracts for a major Standard Metropolitan Statistical Area, can be used to reduce the time and cost of burn injury case reporting by health care providers or case-finding efforts for large population groups, and can be used to predict the effectiveness of social and economic programmes and policies that improve the overall well-being of county populations.

Burns↗
PubMed1990

Paediatric burn injuries in New England, USA.

The authors analysed a subset of data from the New England Regional Burn Program (NERBP) to describe the epidemiology of burn injuries for children aged from birth to 19 years in the six-state New England area of the USA. The subset of the NERBP data analysed pertained to residents of the six New England states who were admitted to hospital for the treatment of a burn injury sustained between 1 July 1978 and 30 June 1979. Analysis of the data revealed that 1128 (41 per cent) of the 2742 hospitalized burns identified occurred to persons between the ages of birth and 19 years, yielding an overall burn incidence rate of 30.7 burns per 100,000 person-years. Children aged from birth to 2 years sustained a higher burn rate, 96.7 burns per 100,000 child-years, than did children in any other age category. The burn rate for males was higher than the rate for females in each age category, as were the rates for black children compared to white children. Children in Massachusetts experienced the highest overall burn rate among the six New England states; the lowest rate occurred in New Hampshire. Overall, 63 per cent of the burns occurred in a residential setting. The most common activities related to burn injury were food preparation and food consumption, which accounted for 471 (42 per cent) of the burn injuries.

Accidents, Home↗