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Biomedical subjects

A Maresta

Publications and source records attributed to A Maresta.

At least 55 records · Page 3Linked to original sources

[Precordial mapping of the QRS complex and Frank's orthogonal ECG in evaluation of the myocardial infarct area. Comparison of the 2 methods].

Precordial mapping of QRS complex is a reliable tool in attempts to quantitate infarct size in patients with acute myocardial infarction. However the recording of multiple precordial leads is an expansive and time-consuming process; the purpose of this study is to investigate the usefulness of Frank's ECG as a substitutive method of infarct sizing. In a group of patients with acute myocardial infarction of the anterior wall many repeated precordial mappings with simultaneous recording of x, y, z leads of Frank's ecg were obtained (71 observations as a whole). Parameters provided by precordial mapping [delta R, delta Q, delta R + delta Q, delta R/delta (Q + S)] and by Frank's ecg (spatial vector voltage deviation of QRS or VSDV-QRS; spatial vector area deviation of QRS or VSDA-QRS; spatial vector R wave deviation or VSDR) were correlated each other by means of linear regression analysis. delta R + delta Q correlated significantly with VSDA QRS (r = 0.54; p less than 0.001) and with VSDR (r = 0.55; p less than 0.001) as regards the total of observations. The correlation coefficient was higher (r = 0.8; p less than 0.001) if comparison between delta R + delta Q and VSDA-QRS was restricted to early 48 hours from the beginning of the symptoms. This could be explained by the greater entity of QRS complex changes in this period, compared to the subsequent course. We conclude that Frank's ecg is an useful alternative method to precordial mapping in sizing the extension of myocardial necrosis.

Electrocardiography

[Rupture of interventricular septum and ventricular aneurysm secondary to acute myocardial infarction in a case with normal coronary arteries (author's transl)].

A patient with ventricular septal defect and ventricular aneurysm after an acute myocardial infarction with normal coronary arteries is reported. Heart failure at 3 weeks after acute myocardial infarction was the indication for surgical treatment. The patient was successfully operated upon with resection of the aneurysm and closure of the ventricular septal defect. Coronary angiography performed before and after cardiac surgery demonstrated a normal coronary tree with transient systolic subocclusion of the left anterior descending coronary artery. The implication of a muscular bridge on the complications of myocardial infarction are discussed.

Heart Aneurysm

[Percutaneous transluminal dilation by catheter of coronary - artery stenosis (author's transl)].

Since September 1977 until July 1979, 82 patients with various coronary lesions have undergone percutaneous transluminal coronary angioplasty (PTCA). By this technic, a catheter system is introduced through a systemic artery under local anesthesia to dilate a stenotic artery by controlled inflation. In 60 patients (73%) anatomical and hemodynamic success could be noted, which led to improvement in clinical parameters e.g. reduction of coronary narrowing of the transluminal diameter from a mean of 82 +/- 11% to 34 +/- 16% (p less than 0.001) and reduction of trans-stenotic coronary gradient from 56 +/- 15 to 19 +/- 12 mmHg (p less than 0.001). Nine patients, three of whom had signs of transmural myocardial infarction on the ECG had undergone emergency surgery for a coronary by-pass, this been due to the deterioration of clinical condition after the attempt to carry out coronary angioplasty. 42 out of 60 treated patients had at least one late control. 33 showed an improvement in cardiac efficiency campared with the pre-dilatation period. Patients with uncalcified single-vessel stenosis, less than 1 cm in length and a short history of pain appear to be most suitable for the procedure. More cases and follow-up datas are necessary to evaluate the efficiency of this new technic as compared with current medical and surgical treatments of ischemic heart disease.

Adult

[Comparison of the hemodynamic effects induced by dobutamine, isoproterenol and dopamine in patients with coronary artery disease (author's transl)].

The haemodynamic affects of dobutamine (DB) (5 microgram/kg/min), isoproterenol (I) (0.02 microgram/kg/min), dopamine (DP) (5 microgram/kg/min), were studied in 12 patients with coronary artery disease randomly divided in two groups of 6 patients. In one group each patient received DB and I, in the other group each patient received DB and DP. The following parameters were measured: heart rate, aortic blood pressure, left ventricular pressure, left ventricular dp/dt, pulmonary arterial and wedge pressure, cardiac output, stroke volume, peripheral and pulmonary vascular resistances. In both groups either I and DP increased significantly heart rate whereas DB did not modifie it. DB caused a larger increase of dp/dt max and of stroke volume as compared to I and DP. These data confirm that DB possesses an inotropic effect greater than I and DP without any significant positive chronotropic effect in patients with coronary artery disease.

Adult