[Xylose test in obese patients treated with near-complete starvation].
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Biomedical subjects
Publications and source records attributed to A Markiewicz.
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The aim of the study was to ascertain whether the acceleration of physical development in children after surgery for ASD or VSD is due to improved intestinal absorption. There were 17 patients with ASD and 9 patients with VSD (aged 5-15 years) examined. Significantly increased values of the xylose test after surgery were found in both groups. The authors suggest that the improvement in intestinal absorption is due to an increase of systemic blood flow after operation. Simultaneously, the stldy confirms, on natural human model, the known dependence between blood flow and the intestinal absorption rate.
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Plasma renin acitivity was measured in II cases of coarctation of the aorta before and after operation. The values of plasma renin activity in the recumbent position before operation were significantly lower than in the control group. After surgery plasma renin activity rose to normal levels. There was no correlation between plasma renin activity levels and arterial blood pressure. The renin-angiotensin system seems not to be involved directly in the maintenance of hypertension in patients with aortic coarctation.
The aim of the study was to ascertain whether the acceleration of physical development in children after operation for coarctation of the aorta is due to the improved intestinal absorption. Lowered values of the oral xylose absorption test were found in all 9 patients before surgery. In all the patients who had been operated on, sphigmo-oscillometry revealed an increased pulsatile character of the blood flow, pulsatile volume in the lower extremities, and a rise of mean arterial blood pressure in this area. On the other hand, surgical repair had no influence on the renal blood flow as evidenced by PAH clearance and isotope renography. There was no correlation of diuresis and the xylose excretion test. Increased values of the xylose test after operation for coarctation of the aorta are due to the increased intestinal absorption rather than to improved renal function. Improved intestinal absorption may be a factor responsible for the accelerated physical development of children operated on for coarctation of the aorta.
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